We narrowed to 5,546 results for: KRAS

1. SpCas9 TadCBEd-V106W

   Plasmid

   #193839

   Purpose

   Express TadCBEd-V106W (with SpCas9) in mammalian cells

   Depositor

   David Liu

   Article

   Neugebauer et al Nat Biotechnol. 2022 Nov 10. pii: 10.103

   Insert

   TadA-CDd V106W-SpCas9 D10A-2xUGI
   

   Expression

   Mammalian

   Available Since

   Dec. 15, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pHS2056

   Plasmid

   #239837

   Purpose

   OMEGAOff + omegaRNA scaffold AAV expression

   Depositor

   Feng Zhang

   Article

   Kannan et al Nat Biotechnol. 2025 May 7. doi: 10.1038

   Insert

   DNMT3A-DNMT3L-NovaIscB-KRAB::NovaIscB omegaRNA scaffold
   

   Use

   AAV

   Tags

   HA and SV40 NLS

   Mutation

   Insertion of REC domain from NbaCas9-1 + E137K/E4…

   Promoter

   EFS; human U6

   Available Since

   July 25, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. peGFP C3-SPG20-PAAA

   Plasmid

   #218581

   Purpose

   Expresses GFP-tagged PPAY motif mutant (PAAA) of human SPG20 in mammalian cells; this mutant does not interact with ITCH

   Depositor

   Hemmo Meyer

   Article

   Gahlot et al Mol Cell. 2024 Mar 14:S1097-2765(24)0017

   Insert

   SPG20 (SPART Human)
   

   Tags

   eGFP

   Expression

   Mammalian

   Mutation

   changed Proline 172 to Alanine and Tyrosine 174 t…

   Promoter

   CMV

   Available Since

   May 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. hPGK_V5-APEX2-GFP

   Plasmid

   #105285

   Purpose

   drives expression of V5-NES-APEX2-GFP from human PGK promotor

   Depositor

   Eugene Yeo

   Article

   Markmiller et al Cell. 2018 Jan 25;172(3):590-604.e13. do

   Insert

   V5-APEX2-NES
   

   Tags

   GFP

   Expression

   Mammalian

   Promoter

   human PGK promoter

   Available Since

   Oct. 25, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-FLEX-SaCas9-U6-sgSlc17a6

   Plasmid

   #124847

   Purpose

   Mutagenesis of Slc17a6 with SauCas9

   Depositor

   Larry Zweifel

   Article

   Hunker et al Cell Rep. 2020 Mar 24;30(12):4303-4316.e

   Insert

   Slc17a6 gRNA (Slc17a6 Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Available Since

   May 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. AA183

   Plasmid

   #216025

   Purpose

   Fragmid fragment: (Cas protein) for prime editing; R221K;N394K for increased efficiency

   Depositor

   John Doench

   Article

   McGee et al Cell Genom. 2024 Mar 13;4(3):100519. doi

   Has Service

   Cloning Grade DNA

   Insert

   nCas9 (H840A)_v2.1 [Sp]
   

   Use

   CRISPR; Fragment

   Available Since

   April 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pTol2CG2-hsp70I:QFGal4-SV40pA

   Plasmid

   #155120

   Purpose

   Tol2 vector for heat-shock inducible expression of QFGal4. Contains cmlc2:mRFP-SV40pA transgenesis marker

   Depositor

   Bret Pearson

   Article

   Burgess et al Dev Biol. 2020 Jul 19. pii: S0012-1606(2

   Insert

   hsp70l:QFGal4 (hsp70l Neurospora crassa, Budding Yeast, Zebrafish)
   

   Use

   Zebrafish expression

   Promoter

   hsp70l

   Available Since

   Sept. 14, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pKL123

   Plasmid

   #187889

   Purpose

   AAVS1 safe-harbor integration of dox-inducible NFIA-SOX9

   Depositor

   Martin Kampmann

   Article

   Leng et al Nat Neurosci. 2022 Nov;25(11):1528-1542.

   Insert

   NFIA-SOX9
   

   Expression

   Mammalian

   Promoter

   TRE3G

   Available Since

   Dec. 5, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTRIP-SFFV-tagBFP-2A-ICP0-FxE

   Plasmid

   #235539

   Purpose

   To express tagBFP-2A-ICP0-FXE (ICP0 ∆106-149)

   Depositor

   Nicolas Manel

   Article

   Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

   Insert

   ICP0-FxE
   

   Use

   Lentiviral

   Mutation

   Deletion of the RING domain, ∆106-149.

   Available Since

   July 17, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCIRCgp41-1

    Plasmid

    #74227

    Purpose

    Vector for SICLOPPS-mediated protein circularization using the gp41-1 intein.

    Depositor

    Roland Eils, Barbara Di Ventura

    Article

    Waldhauer et al Mol Biosyst. 2015 Nov 10;11(12):3231-43.

    Type

    Empty backbone

    Use

    Synthetic Biology

    Tags

    gp41-1 C-intein and gp41-1 N-intein

    Expression

    Bacterial

    Promoter

    T7-lac

    Available Since

    April 15, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. pGEX-6P-1 p37deltaSEP

    Plasmid

    #113501

    Purpose

    Bacterial expression of GST-tagged p37 lacking the SEP domain

    Depositor

    Hemmo Meyer

    Article

    Weith et al Mol Cell. 2018 Oct 11. pii: S1097-2765(1

    Insert

    p37 (Ubxn2b Mouse)
    

    Tags

    GST-PreScission protease site

    Expression

    Bacterial

    Mutation

    delta 140-206

    Available Since

    Oct. 11, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. WN10150

    Plasmid

    #80443

    Purpose

    Expresses dead (908A) AsCpf1

    Depositor

    Ervin Welker

    Article

    Toth et al Nucleic Acids Res. 2018 Sep 20. pii: 510

    Insert

    nuclease dead (908A) AsCpf1
    

    Tags

    NLS-3xHA

    Expression

    Mammalian

    Mutation

    nuclease dead (D908A)

    Available Since

    Aug. 29, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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13. pET28A-Rab8A

    Plasmid

    #228880

    Purpose

    Expression of His-tagged Rab8A in E. coli

    Depositor

    Sebastian Mathea

    Article

    Raig et al bioRxiv [Preprint]. 2025 Feb 13:2024.09.

    Insert

    RAB8A (RAB8A Human)
    

    Tags

    His tag

    Expression

    Bacterial

    Mutation

    residues 1-6 and 177-207 missing

    Available Since

    Jan. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. PET-B-Sniper SpCas9-NLS-6xHis

    Plasmid

    #207377

    Purpose

    Expression of increased-fidelity (i.e. high-fidelity) SpCas9 variant in bacterial cells

    Depositor

    Ervin Welker

    Article

    Kulcsar et al Nat Commun. 2023 Sep 16;14(1):5746. doi:

    Insert

    B-Sniper SpCas9
    

    Use

    CRISPR

    Tags

    6xHis

    Expression

    Bacterial

    Mutation

    F539S, M763I, K890N, amino acids 1005-1013 replac…

    Promoter

    T7

    Available Since

    Sept. 25, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pDY1462_SERPINA1_CCA32_Caspase

    Plasmid

    #193194

    Purpose

    Express Caspase conditional upon RNA transcript

    Depositor

    Omar Abudayyeh, Jonathan Gootenberg

    Article

    Jiang et al Nat Biotechnol. 2022 Oct 27. pii: 10.103

    Insert

    iCaspase9 (CASP9 Human)
    

    Expression

    Mammalian

    Available Since

    Nov. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. pcDNA3.1-Flag-Sintbad

    Plasmid

    #234668

    Purpose

    expresses SINTBAD (TBKBP1) in mammalian cells

    Depositor

    Lienhard Schmitz

    Article

    Saul et al iScience. 2019 Sep 27;19:527-544. doi: 1

    Insert

    SINTBAD (TBKBP1 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    April 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. 3XFLAG_GAPDH in pCW57_tTA_Blast

    Plasmid

    #154211

    Purpose

    Dox-off lentivirus construct all-in-one vector, with Blast resistance, for expression of GAPDH

    Depositor

    David Sabatini

    Article

    Orozco et al Nat Metab. 2020 Sep;2(9):893-901. doi: 1

    Insert

    GAPDH (GAPDH Human)
    

    Use

    Lentiviral

    Tags

    3X FLAG

    Expression

    Mammalian

    Promoter

    TRE repeats (dox off)

    Available Since

    Oct. 28, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. p2T-cmv-SpCas9-TadCBEd-BlastR

    Plasmid

    #193848

    Purpose

    Express TadCBEd in mammalian cells with BlastR selection, Tol2 integration

    Depositor

    David Liu

    Article

    Neugebauer et al Nat Biotechnol. 2022 Nov 10. pii: 10.103

    Insert

    TadCBEd
    

    Expression

    Mammalian

    Available Since

    Dec. 15, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. PET-Sniper SpCas9-NLS-6xHis

    Plasmid

    #207374

    Purpose

    Expression of increased-fidelity (i.e. high-fidelity) SpCas9 variant in bacterial cells

    Depositor

    Ervin Welker

    Article

    Kulcsar et al Nat Commun. 2023 Sep 16;14(1):5746. doi:

    Insert

    Sniper SpCas9
    

    Use

    CRISPR

    Tags

    6xHis

    Expression

    Bacterial

    Mutation

    F539S, M763I, K890N

    Promoter

    T7

    Available Since

    Sept. 25, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pEasiLV-MCS-coICP0fxe

    Plasmid

    #235546

    Purpose

    To express ICP0-FXE (ICP0 ∆106-149, doxycycline inducible)

    Depositor

    Nicolas Manel

    Article

    Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

    Insert

    ICP0
    

    Use

    Lentiviral

    Mutation

    Deletion of the RING domain, ∆106-149.

    Available Since

    July 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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