We narrowed to 3,403 results for: aaas

1. FGFR2 gRNA (BRDN0001148071)

   Plasmid

   #76182

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human FGFR2

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   FGFR2 (FGFR2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. FLAG-YAP2 (8SA)-pcw107

   Plasmid

   #64637

   Purpose

   when used to produce lentivirus, express physiological levels of insert

   Depositor

   David Sabatini, Kris Wood

   Article

   Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

   Insert

   YAP2 (transcript variant 3) (YAP1 Human)
   

   Use

   Lentiviral

   Tags

   FLAG

   Mutation

   8SA*

   Promoter

   PGK

   Available Since

   Dec. 8, 2015

   Availability

   Academic Institutions and Nonprofits only

3. px330-Apob-4

   Plasmid

   #162551

   Purpose

   sgRNA targeting Apob

   Depositor

   Amaia Lujambio

   Article

   Molina-Sanchez et al Gastroenterology. 2020 Aug 16. pii: S001

   Insert

   sgRNA targeting Apob (Apob Mouse)
   

   Expression

   Mammalian

   Mutation

   None

   Promoter

   U6

   Available Since

   Feb. 16, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. sgALK(Chr. Inv.)

   Plasmid

   #85569

   Purpose

   Expresses sgRNA targeting human ALK between exon 20 and 21

   Depositor

   Luca Grumolato

   Article

   Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

   Insert

   anaplastic lymphoma receptor tyrosine kinase (ALK Human)
   

   Expression

   Mammalian

   Available Since

   Feb. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

5. TTN gRNA (BRDN0001145502)

   Plasmid

   #76851

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human TTN

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   TTN (TTN Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. TTN gRNA (BRDN0001148106)

   Plasmid

   #76854

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human TTN

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   TTN (TTN Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. KHC065 pBABE pU6 BRD2 K1-2C

   Plasmid

   #231712

   Purpose

   KHC065 (pBABE pU6 BRD2 K1-2C), gRNA and cas9D10A mammalian expression vector for CRISPR mediated cutting of BRD2 at the N-terminus, use with KHC064

   Depositor

   Alessio Ciulli

   Article

   Bond et al J Med Chem. 2021 Oct 28;64(20):15477-155

   Insert

   gRNA for Brd2 and Cas9D10A (BRD2 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Feb. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. PX459-CTNNA1(α-catenin CRISPR KO)

   Plasmid

   #229708

   Purpose

   Knockout of a-catenin in mammalian cells using CRISPR-Cas9 technology

   Depositor

   Alpha Yap

   Article

   Noordstra et al Dev Cell. 2023 Sep 25;58(18):1748-1763.e

   Insert

   CTNNA1 (alpha-catenin) Human (CTNNA1 Human)
   

   Expression

   Mammalian

   Promoter

   CMV promoter

   Available Since

   Jan. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. sgLATS1/2-1

   Plasmid

   #229431

   Purpose

   knockout of LATS1 and LATS2

   Depositor

   Christopher Vakoc

   Article

   Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

   Insert

   sgLATS1/2-1 (LATS1, LATS2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6;bU6;EFS

   Available Since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. sgMST1/2-1

    Plasmid

    #229429

    Purpose

    knockout of MST1 and MST2

    Depositor

    Christopher Vakoc

    Article

    Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

    Insert

    sgMST1/2-1 (MST1, STK3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6;bU6;EFS

    Available Since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. Cdk13_intron3_sg4_pX458

    Plasmid

    #127339

    Purpose

    sgRNA that cuts within intron 3 of mouse CDK13 genomic locus- guide #4

    Depositor

    Phil Sharp

    Article

    Insco et al Science. 2023 Apr 21;380(6642):eabn7625.

    Insert

    Mouse Cdk13 Intron 3 sgRNA (Cdk13 Mouse)
    

    Use

    CRISPR and Mouse Targeting

    Promoter

    U6 Promoter

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pKLV2-U6gRNA5(CXCR4-E1(15))-PGKpuro2ABFP-W

    Plasmid

    #200478

    Purpose

    Lentiviral vector expressing gRNA targeting human CXCR4-E1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CXCR4-E1(15) (CXCR4 Human)
    

    Use

    Lentiviral

    Available Since

    April 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. px552-U6-gRNA1-CMV-eGFP

    Plasmid

    #211758

    Purpose

    sgRNA1 targeting Exon 1 of VEGFA gene conserved across mouse, rhesus macaque, and human.

    Depositor

    Glenn Yiu

    Article

    Chung et al Mol Ther Nucleic Acids. 2022 Apr 27;28:6

    Insert

    gRNA1 targeting VEGF-A (VEGFA Human, M. mulatta (rhesus macaque), Mouse)
    

    Use

    AAV and CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pKLV2-U6gRNA5(BCL11B-E3(32))-PGKpuro2ABFP-W

    Plasmid

    #208557

    Purpose

    Lentiviral vector expressing gRNA targeting human BCL11B-E3

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    BCL11B-E3(32) (BCL11B Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pKLV2.2-h7SKgRNA5(RUNX1(13))-hU6gRNA5(RUNX3(12))-PGKpuroBFP-W

    Plasmid

    #208569

    Purpose

    Lentiviral vector expressing gRNA targeting human RUNX1 and RUNX3

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    RUNX1(13), RUNX3(12) (RUNX1, RUNX3 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pKLV2.2-h7SKgRNA5(RUNX1(13))-hU6gRNA5(RUNX3(13))-PGKpuroBFP-W

    Plasmid

    #208570

    Purpose

    Lentiviral vector expressing gRNA targeting human RUNX1 and RUNX3

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    RUNX1(13), RUNX3(13) (RUNX1, RUNX3 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pKLV2-U6gRNA5(BCL11B-E2(25))-PGKpuro2ABFP-W

    Plasmid

    #208556

    Purpose

    Lentiviral vector expressing gRNA targeting human BCL11B-E2

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    BCL11B-E2(25) (BCL11B Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pKLV2.2-h7SKgRNA5(ARID1A(44))-hU6gRNA5(AAVS1)-PGKpuroBFP-W

    Plasmid

    #200506

    Purpose

    Lentiviral vector expressing gRNA targeting human ARID1A and AAVS1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    ARID1A(44), AAVS1 (ARID1A, AAVS1 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pKLV2-U6gRNA5(CXCR4(16))-PGKpuro2ABFP-W

    Plasmid

    #200461

    Purpose

    Lentiviral vector expressing gRNA targeting human CXCR4

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CXCR4(16) (CXCR4 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pKLV2-U6gRNA5(ARID1B(21))-PGKpuro2ABFP-W

    Plasmid

    #200469

    Purpose

    Lentiviral vector expressing gRNA targeting human ARID1B

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    ARID1B(21) (ARID1B Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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