We narrowed to 2,163 results for: PAM

1. pJT311 AAV-Rapamycin Inducible-NZF-Citrine

   Plasmid

   #202060

   Purpose

   Inducible AAV activator

   Depositor

   Lacra Bintu, Michael Bassik

   Article

   Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038

   Insert

   AAV-Rapamycin Inducible-NZF-Citrine
   

   Use

   AAV; Aav with reporter

   Expression

   Mammalian

   Mutation

   ITR deletion

   Available Since

   May 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pUC19-HDRT-TRAC-CD19.CAR-Cas12a.PAM.mutated

   Plasmid

   #215769

   Purpose

   encodes for HDR template for optimized AsCas12a-mediated knock-in of a CD19-specific CAR into the TRAC locus

   Depositor

   Dimitrios Wagner

   Article

   Glaser et al Genome Biol. 2023 Apr 24;24(1):89. doi:

   Inserts

   TRAC-5' homology arm (TRAC Human)
   P2A-CD19.28.zeta-bgH (CD19 Human, Mouse, Bovine)
   TRAC-3' homology arm (TRAC Human)
   

   Expression

   Bacterial

   Mutation

   Cas12a PAM mutated

   Available Since

   June 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLenti-TO/CMV-puro-DD-PAmCherry1-KRas G12D

   Plasmid

   #177320

   Purpose

   Lentiviral vector expressing PAmCherry1-tagged KRas 4B G12D mutant, with an N-terminal dimerization domain (DD).

   Depositor

   Steven Chu, Xiaolin Nan

   Article

   Nan et al Proc Natl Acad Sci U S A. 2015 Jun 30;11

   Insert

   KRAS 4B (KRAS Human)
   

   Use

   Lentiviral

   Tags

   FKBP-derived dimerization domain (DD, or DmrB) an…

   Expression

   Mammalian

   Mutation

   G12D

   Promoter

   TetOn-CMV

   Available Since

   Jan. 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLV-CMV-EGFP-PolB-PAMmut-Hygro

   Plasmid

   #176086

   Purpose

   EGFP fused to the N-terminus of a POLB containing a mutation in the PAM site used by POLBKOg1 & a hygromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

   Insert

   PolB (POLB Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   Mutation in the PAM site used by PolBKOg1

   Promoter

   CMV

   Available Since

   Jan. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLenti-EF1a-CDK6-mutPAM-PGK-puro

   Plasmid

   #187638

   Purpose

   sg resistant CDK6 ORF

   Depositor

   William Kaelin

   Article

   Nicholson et al Sci Signal. 2019 Oct 1;12(601). pii: 12/

   Insert

   CDK6 (CDK6 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   PAM site mutation

   Available Since

   Aug. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pJT315 AAV-Rapamycin Inducible-ZNF473KRAB-Citrine

   Plasmid

   #202064

   Purpose

   Inducible AAV activator

   Depositor

   Lacra Bintu, Michael Bassik

   Article

   Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038

   Insert

   AAV-Rapamycin Inducible-ZNF473KRAB-Citrine
   

   Use

   AAV; Aav with reporter

   Expression

   Mammalian

   Mutation

   ITR deletion

   Available Since

   May 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAc5.1B-EGFP-DmGW182-PAM26B-F1370A-dsRNAres_L

   Plasmid

   #146838

   Purpose

   Insect Expression of DmGW182-PAM26B-F1370A-dsRNAres

   Depositor

   Elisa Izaurralde

   Article

   Huntzinger et al EMBO J. 2010 Dec 15;29(24):4146-60. doi:

   Insert

   DmGW182-PAM26B-F1370A-dsRNAres (gw Fly)
   

   Expression

   Insect

   Mutation

   Two non silent mutations V704A and N799S and one …

   Available Since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAM/CBA-eGFP-miRNegativex3-WPRE-bGHpA

   Plasmid

   #194249

   Purpose

   Expresses 3 non-targeting miRNAs

   Depositor

   Michael J Fox Foundation MJFF

   Insert

   miRNegative
   

   Use

   AAV and RNAi

   Promoter

   CAG

   Available Since

   March 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLV-Hygro-Ef1A-Myc-POLB(PAMmut)

   Plasmid

   #176150

   Purpose

   N-terminus Myc-tagged POLB containing a mutation in the PAM site used by POLB gRNA1 & a hygromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

   Insert

   PolB (POLB Human)
   

   Use

   Lentiviral

   Tags

   MYC

   Expression

   Mammalian

   Mutation

   Mutation in the PAM site used by POLB gRNA1

   Promoter

   EF1A

   Available Since

   Feb. 10, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAM-CAGGS-FLEX-H2B-3XHA-P2A-N2c(G)

    Plasmid

    #73477

    Purpose

    Encodes the G protein to enable transsynaptic RAV infection

    Depositor

    Thomas Jessell

    Article

    Reardon et al Neuron. 2016 Jan 19. pii: S0896-6273(16)

    Insert

    H2B-3XHA-P2A-N2c(G)
    

    Use

    AAV

    Available Since

    March 21, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAM/CBA-eGFP-miRaSyn(human)x3-WPRE-bGHpA

    Plasmid

    #194247

    Purpose

    Expresses 3 miRNAs targeting human alpha-Synuclein

    Depositor

    Michael J Fox Foundation MJFF

    Insert

    miRaSynuclein(human) (SNCA Human)
    

    Use

    AAV and RNAi

    Promoter

    CAG

    Available Since

    Jan. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAM/SAR-CAG-aSyn(A53T)/HA-WPRE-bGHpA

    Plasmid

    #194242

    Purpose

    Expresses human alpha-Synuclein A53T

    Depositor

    Michael J Fox Foundation MJFF

    Insert

    aSynuclein(A53T) (SNCA Human)
    

    Use

    AAV

    Tags

    HA

    Mutation

    A53T

    Promoter

    SAR-CAG

    Available Since

    Jan. 24, 2023

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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13. pJT410 AAV-Rapamycin Inducible-NFZ-Citrine with bGH pA

    Plasmid

    #202059

    Purpose

    Inducible AAV activator

    Depositor

    Lacra Bintu, Michael Bassik

    Article

    Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038

    Insert

    AAV-Rapamycin Inducible-NFZ-Citrine with bGH pA
    

    Use

    AAV; Aav with reporter

    Expression

    Mammalian

    Mutation

    ITRs intact

    Available Since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pAM-CAGGS-FLEX-H2B-GFP-P2A-N2c(G)

    Plasmid

    #73475

    Purpose

    Encodes the G protein to enable transsynaptic RAV infection

    Depositor

    Thomas Jessell

    Article

    Reardon et al Neuron. 2016 Jan 19. pii: S0896-6273(16)

    Insert

    H2B-GFP-P2A-N2c(G)
    

    Use

    AAV

    Available Since

    March 21, 2016

    Availability

    Academic Institutions and Nonprofits only

15. pAM/CBA-eGFP-miRaSyn(mouse)x3-WPRE-bGHpA

    Plasmid

    #194248

    Purpose

    Expresses 3 miRNAs targeting mouse alpha-Synuclein

    Depositor

    Michael J Fox Foundation MJFF

    Insert

    miRaSynuclein(mouse) (Snca Mouse)
    

    Use

    AAV and RNAi

    Promoter

    CAG

    Available Since

    Jan. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCIneo-PAM-sig-His6-gamma-PALcc-deltaGlyc

    Plasmid

    #25458

    Depositor

    Betty Eipper

    Article

    Chufan et al Structure. 2009 Jul 15. 17(7):965-73.

    Insert

    PAM (Pam Rat)
    

    Tags

    His6 and PAM signal

    Expression

    Mammalian

    Mutation

    Contains aa 498-820 (PALcc= PAL catalytic core) …

    Available Since

    July 13, 2010

    Availability

    Academic Institutions and Nonprofits only

17. pAM316 pET28a-GGG-Titin[V15P]-23-K-9-C-14cyclinB-10GS-Y

    Plasmid

    #226349

    Purpose

    Expression of Titin V15P substrate with GS tail

    Depositor

    Andreas Martin

    Article

    Jonsson et al Sci Adv. 2022 Dec 23;8(51):eadd9520. doi

    Insert

    titin (TTN Human)
    

    Expression

    Bacterial

    Mutation

    V15P

    Available Since

    Oct. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pJT360 AAV-Rapamycin Inducible-noActivator Domain -Citrine

    Plasmid

    #202058

    Purpose

    Inducible AAV with reporter gene and cloning site to add activator domains

    Depositor

    Lacra Bintu, Michael Bassik

    Article

    Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038

    Insert

    AAV-Rapamycin Inducible-noActivator Domain -Citrine
    

    Use

    AAV; Aav with reporter

    Expression

    Mammalian

    Mutation

    ITRs intact

    Available Since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLV-CMV-EGFP-PolB(K72A)-PAMmut-Hygro

    Plasmid

    #176087

    Purpose

    EGFP fused to the N-terminus of POLB containing the mutation Lys72Ala, a mutation in the PAM site used by POLBKOg1 & a hygromycin resistance cassette

    Depositor

    Robert Sobol

    Article

    Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

    Insert

    PolB (POLB Human)
    

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Mutation in Lys72 to Ala, and mutation in the PAM…

    Promoter

    CMV

    Available Since

    Jan. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. Anti-Dopamine D2 receptor [N186/29R] (Recombinant Antibody)

    Antibody

    #184204-rAb

    Purpose

    Anti-Dopamine D2 receptor (Rat) recombinant mouse monoclonal antibody. Recognizes long and short forms.

    Depositor

    James Trimmer

    Article

    Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

    Recommended Applications

    Immunohistochemistry

    Reactivity

    Mouse and Rat

    Source Species

    Mouse

    Isotype

    IgG2a

    Trial Size

    Available to purchase

    Available Since

    Aug. 22, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits