Purpose
Expresses full length SRGAP2 with R527L, K566A mt in the Rac1-specific GAP domain that abrogates the GTPase activating function of SRGAP2 without locking the GAP-domain in a form bound to Rac1-GDP.
Mutation
Point mutations R527L and K566A (Rac1-specific GA…
Available Since
Oct. 9, 2024
Availability
Academic Institutions and Nonprofits only