We narrowed to 153,292 results for: des

1. pGEX-4T-3 SIRT1-NTerm Exon1-Exon3

   Plasmid

   #105681

   Purpose

   Bacterial Expression construct of N terminus of SIRT1: Exon1-Exon3 (deltaExon2)

   Depositor

   Ullas Kolthur-Seetharam

   Article

   Deota et al Cell Rep. 2017 Mar 28;18(13):3069-3077.

   Insert

   SIRT1-NTerm: Exon1-Exon3 (Sirt1 Mouse)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Synonymous base changes not affecting the protein…

   Promoter

   tac_Promoter

   Available since

   April 6, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pGEX-4T-3- SIRT1-NTerm Exon1-Exon2-Exon3

   Plasmid

   #105680

   Purpose

   Bacterial Expression construct of N terminus of SIRT1: Exon1-Exon2-Exon3

   Depositor

   Ullas Kolthur-Seetharam

   Article

   Deota et al Cell Rep. 2017 Mar 28;18(13):3069-3077.

   Insert

   SIRT1-NTerm: Exon1-Exon2-Exon3 (Sirt1 Mouse)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Synonymous base changes not affecting the protein…

   Promoter

   tac_Promoter

   Available since

   April 6, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. Adeno FT

   Plasmid

   #101824

   Purpose

   Adenovirus for the expression of gRNAs targeting intron 17 of murine Fgfr3 and intron 6 of murine Tacc3

   Depositor

   Andrea Ventura

   Article

   Cook et al Nat Commun. 2017 Jul 11;8:15987. doi: 10

   Insert

   U6_sgRNA(Fgfr3)_U6_sgRNA(Tacc3)_CBh_FLAG-Cas9 (Fgfr3, Tacc3 Mouse)
   

   Use

   Adenoviral

   Tags

   FLAG-Cas9

   Expression

   Mutation

   Promoter

   U6 and CBh

   Available since

   Nov. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

4. Adeno BN

   Plasmid

   #101823

   Purpose

   Adenovirus for the expression of gRNAs targeting intron 13 of murine Bcan and intron 10 of murine Ntrk1

   Depositor

   Andrea Ventura

   Article

   Cook et al Nat Commun. 2017 Jul 11;8:15987. doi: 10

   Insert

   U6_sgRNA(Bcan)_U6_sgRNA(Ntrk1)_CBh_FLAG-Cas9 (Bcan, Ntrk1 Mouse)
   

   Use

   Adenoviral

   Tags

   FLAG-Cas9

   Expression

   Mutation

   Promoter

   Available since

   Nov. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

5. pcDNA3-CARMA2sh-delta458-500

   Plasmid

   #97074

   Purpose

   Expresses mutant CARD14/CARMA2 in mammalian cells

   Depositor

   Pasquale Vito

   Article

   Scudiero et al Cell Death Dis. 2017 Feb 23;8(2):e2627.

   Insert

   CARD14 isoform 3 (CARD14 Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   deleted amino acids 458-500

   Promoter

   CMV

   Available since

   Aug. 16, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pENTR-2B-Nkx2-5 Y191C

   Plasmid

   #98613

   Purpose

   Gateway entry vector for NKX2-5 Y191C

   Depositor

   Richard Harvey

   Article

   Bouveret et al Elife. 2015 Jul 6;4. doi: 10.7554/eLife.

   Insert

   NKX2-5 Y191C (Nkx2-5 Mouse)
   

   Use

   Entry vector

   Tags

   Expression

   Mutation

   Point mutation Y191C

   Promoter

   Available since

   July 26, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pCR8/GW/TOPO-ELK1Y158A

   Plasmid

   #98628

   Purpose

   Gateway entry TOPO TA cloning vector ELK1 Y158A

   Depositor

   Richard Harvey

   Article

   Bouveret et al Elife. 2015 Jul 6;4. doi: 10.7554/eLife.

   Insert

   ELK1 Y158A (Elk1 Mouse)
   

   Use

   Topo ta cloning vector

   Tags

   Expression

   Mutation

   Y158A

   Promoter

   Available since

   July 13, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pAav-IQGAP1-PQS1-3xFLAG

   Plasmid

   #84885

   Purpose

   rAAV-based template for genome engineering of the IQGAP1 C-terminus containing PQS1 and 3xFLAG tags and a selection cassette

   Depositor

   Sven Eyckerman

   Article

   Vandemoortele et al Sci Rep. 2016 Jun 6;6:27220. doi: 10.103

   Inserts

   IQGAP1 genomic region HR1 (IQGAP1 Human)
   IQGAP1 genomic region HR2
   

   Use

   AAV

   Tags

   PQS1 3xFLAG

   Expression

   Mutation

   Promoter

   no

   Available since

   Nov. 28, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pAav-TP53-PQS1-3xFLAG

   Plasmid

   #84884

   Purpose

   rAAV-based template for genome engineering of the p53 C-terminus containing PQS1 and 3xFLAG tags and a selection cassette

   Depositor

   Sven Eyckerman

   Article

   Vandemoortele et al Sci Rep. 2016 Jun 6;6:27220. doi: 10.103

   Inserts

   TP53 genomic region HR1 (TP53 Human)
   TP53 genomic region HR2
   

   Use

   AAV

   Tags

   PQS1 3xFLAG

   Expression

   Mutation

   Promoter

   no and no

   Available since

   Nov. 28, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. LAMTOR3 gRNA (BRDN0001147669)

    Plasmid

    #77136

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human LAMTOR3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    LAMTOR3 (LAMTOR3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 18, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. CROT gRNA (BRDN0001145682)

    Plasmid

    #77709

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CROT

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CROT (CROT Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 18, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. KALRN gRNA (BRDN0001145005)

    Plasmid

    #77639

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human KALRN

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    KALRN (KALRN Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 14, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. NPR2 gRNA (BRDN0001148355)

    Plasmid

    #77753

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human NPR2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    NPR2 (NPR2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 14, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. CAMK2B gRNA (BRDN0001148102)

    Plasmid

    #77742

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CAMK2B

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CAMK2B (CAMK2B Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 14, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. AURKA gRNA (BRDN0001145351)

    Plasmid

    #77728

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKA

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AURKA (AURKA Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 13, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. CDK5R1 gRNA (BRDN0001145710)

    Plasmid

    #77851

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK5R1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK5R1 (CDK5R1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 13, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. IPMK gRNA (BRDN0001146121)

    Plasmid

    #78075

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human IPMK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    IPMK (IPMK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. C17orf75 gRNA (BRDN0001145175)

    Plasmid

    #78077

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human C17orf75

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    C17orf75 (C17orf75 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. C17orf75 gRNA (BRDN0001146368)

    Plasmid

    #78078

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human C17orf75

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    C17orf75 (C17orf75 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. C17orf75 gRNA (BRDN0001487133)

    Plasmid

    #78079

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human C17orf75

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    C17orf75 (C17orf75 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. LRGUK gRNA (BRDN0001145468)

    Plasmid

    #78084

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human LRGUK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    LRGUK (LRGUK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. LRGUK gRNA (BRDN0001147114)

    Plasmid

    #78085

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human LRGUK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    LRGUK (LRGUK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. LRGUK gRNA (BRDN0001487051)

    Plasmid

    #78086

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human LRGUK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    LRGUK (LRGUK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. AURKC gRNA (BRDN0001146500)

    Plasmid

    #78054

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKC

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AURKC (AURKC Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. AURKC gRNA (BRDN0001487140)

    Plasmid

    #78055

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKC

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AURKC (AURKC Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. AURKC gRNA (BRDN0001148441)

    Plasmid

    #78056

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKC

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AURKC (AURKC Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. DCK gRNA (BRDN0001148859)

    Plasmid

    #78057

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DCK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DCK (DCK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. DCK gRNA (BRDN0001487070)

    Plasmid

    #78058

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DCK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DCK (DCK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. FASTKD3 gRNA (BRDN0001146235)

    Plasmid

    #78064

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FASTKD3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FASTKD3 (FASTKD3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. FASTKD3 gRNA (BRDN0001147359)

    Plasmid

    #78065

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FASTKD3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FASTKD3 (FASTKD3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. FASTKD3 gRNA (BRDN0001487108)

    Plasmid

    #78066

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FASTKD3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FASTKD3 (FASTKD3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. CKM gRNA (BRDN0001487098)

    Plasmid

    #78031

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CKM

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CKM (CKM Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. DGKH gRNA (BRDN0001144863)

    Plasmid

    #78043

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DGKH

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DGKH (DGKH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. DGKH gRNA (BRDN0001487100)

    Plasmid

    #78044

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DGKH

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DGKH (DGKH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. DGKH gRNA (BRDN0001149163)

    Plasmid

    #78045

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DGKH

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DGKH (DGKH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. BRSK2 gRNA (BRDN0001146828)

    Plasmid

    #78025

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human BRSK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    BRSK2 (BRSK2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. BRSK2 gRNA (BRDN0001147787)

    Plasmid

    #78027

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human BRSK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    BRSK2 (BRSK2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. CKM gRNA (BRDN0001148014)

    Plasmid

    #78028

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CKM

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CKM (CKM Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. CKM gRNA (BRDN0001146579)

    Plasmid

    #78029

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CKM

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CKM (CKM Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. CKM gRNA (BRDN0001148653)

    Plasmid

    #78030

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CKM

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CKM (CKM Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge