We narrowed to 4,851 results for: AAT

1. pLL5.0 shCavin1KDR-EGFP

   Plasmid

   #187254

   Purpose

   Lentiviral expression of shRNA targeting Cavin1 + reconstitution of mouse Cavin1 (Cavin1 rescue)

   Depositor

   Alpha Yap

   Article

   Teo et al Dev Cell. 2020 Jul 6;54(1):75-91.e7. doi

   Insert

   ShRNA for Cavin1 (Cavin1 Mouse)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mutation

   Promoter

   U6, 5'LTR

   Available since

   Feb. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. Control-TP53-LRG-GFP

   Plasmid

   #225874

   Purpose

   Guides targeting P53 and a control sequence

   Depositor

   Janai Carr-Ascher

   Article

   Freeland et al Clin Cancer Res. 2024 Aug 23. doi: 10.11

   Insert

   Control and TP53 (TP53 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Oct. 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. Control-RB1-LRG-GFP

   Plasmid

   #225875

   Purpose

   Guides targeting RB1 and a control sequence

   Depositor

   Janai Carr-Ascher

   Article

   Freeland et al Clin Cancer Res. 2024 Aug 23. doi: 10.11

   Insert

   Control and RB1 (RB1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   Oct. 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pSuper Retro GFP DGK zeta mouse

   Plasmid

   #224577

   Purpose

   Negative Control for downregulation of the expression of human DGK zeta in human cells

   Depositor

   Isabel Mérida

   Article

   Torres-Ayuso et al Oncotarget. 2014 Oct 30;5(20):9710-26. d

   Insert

   sh RNAi Diacylglycerol kinase zeta mouse (Dgkz Mouse)
   

   Use

   RNAi and Retroviral

   Tags

   Expression

   Mutation

   Promoter

   H1

   Available since

   Sept. 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pMXS-IRES-BLAST flag-CAD M1601E

   Plasmid

   #169828

   Purpose

   Expresses C-terminal flag-tagged CAD with mutation at reported dimerization interface of the DHOase domain

   Depositor

   Richard Possemato

   Article

   Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

   Insert

   CAD (CAD Human)
   

   Use

   Retroviral

   Tags

   Flag tag

   Expression

   Mammalian

   Mutation

   M1601E; TCCC -> AGTC silent mutations at nt527…

   Promoter

   Available since

   July 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pMXS-IRES-BLAST flag-CAD S1406A

   Plasmid

   #169820

   Purpose

   Expresses C-terminal flag-tagged CAD with mutation of reported PKA phosphorylation site

   Depositor

   Richard Possemato

   Article

   Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

   Insert

   CAD (CAD Human)
   

   Use

   Retroviral

   Tags

   Flag tag

   Expression

   Mammalian

   Mutation

   S1406A; TCCC -> AGTC silent mutations at nt527…

   Promoter

   Available since

   July 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pMXS-IRES-BLAST flag-CAD S1859E

   Plasmid

   #169822

   Purpose

   Expresses C-terminal flag-tagged CAD with mutation of reported S6K phosphorylation site

   Depositor

   Richard Possemato

   Article

   Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

   Insert

   CAD (CAD Human)
   

   Use

   Retroviral

   Tags

   Flag tag

   Expression

   Mammalian

   Mutation

   S1859E; TCCC -> AGTC silent mutations at nt527…

   Promoter

   Available since

   July 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. LMPd Amt PHGDH

   Plasmid

   #209409

   Purpose

   Retroviral vector with Ametrine marker for expressing shRNA with an "UltramiR" microRNA scaffold

   Depositor

   Russell Jones

   Article

   Ma et al Immunity. 2019 Nov 19;51(5):856-870.e5.

   Insert

   Phgdh shRNA (Phgdh Mouse)
   

   Use

   Retroviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   May 7, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pKLV2-U6gRNA5(ETS2_5-5)-PGKpuroBFP-W

   Plasmid

   #211959

   Purpose

   Express gRNA against ETS2 with puro and BFP

   Depositor

   Kosuke Yusa

   Article

   Ishikawa et al Commun Biol. 2023 Dec 28;6(1):1290. doi:

   Insert

   sgRNA targeting ETS2 (ETS2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Human U6 promoter

   Available since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pKLV2-U6gRNA5(CDK6-E2(12))-PGKpuro2ABFP-W

    Plasmid

    #200488

    Purpose

    Lentiviral vector expressing gRNA targeting human CDK6-E2

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CDK6-E2(12) (CDK6 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pKLV2-U6gRNA5(CDK6-E1(1))-PGKpuro2ABFP-W

    Plasmid

    #200486

    Purpose

    Lentiviral vector expressing gRNA targeting human CDK6-E1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CDK6-E1(1) (CDK6 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pKLV2-U6gRNA5(CDK6-E2(15))-PGKpuro2ABFP-W

    Plasmid

    #200489

    Purpose

    Lentiviral vector expressing gRNA targeting human CDK6-E2

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CDK6-E2(15) (CDK6 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pUC-hU6-shBACH1_BFP

    Plasmid

    #199217

    Purpose

    Expression plasmid with shRNAmiR targeting BACH1, with a BFP reporter on the backbone. 

    Depositor

    Gabor Balazsi

    Article

    Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d

    Insert

    shBACH1 (BACH1 Synthetic)
    

    Use

    RNAi

    Tags

    Expression

    Mutation

    Promoter

    human U6

    Available since

    Aug. 2, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pUC_hU6-shRKIP_BFP

    Plasmid

    #199216

    Purpose

    Expression plasmid with shRNAmiR targeting RKIP (PEBP1), with a BFP reporter on the backbone.

    Depositor

    Gabor Balazsi

    Article

    Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d

    Insert

    shBACH1 (BACH1 Synthetic)
    

    Use

    RNAi

    Tags

    Expression

    Mutation

    Promoter

    human U6

    Available since

    June 28, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. MDM4_CRISPRi_gRNA_2

    Plasmid

    #195133

    Purpose

    gRNA from the Weissman CRISPRi library targeting MDM4, cloned into a third generation gRNA backbone with mCherry

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    MDM4 CRISPRi gRNA 2 (MDM4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. 2X_pX458_pSpCas9(BB)-2A-GFP_eSOX17.2_KO

    Plasmid

    #195495

    Purpose

    Cas9-2A-GFP expression vector bearing two sgRNAs targeting the core endoderm distal enhancer of human SOX17

    Depositor

    Alexander Meissner

    Article

    Landshammer et al Elife. 2023 Jan 31;12:e83077. doi: 10.75

    Insert

    sgRNA (SOX17 Human)
    

    Use

    CRISPR

    Tags

    3XFLAG and GFP

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Feb. 2, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. eIF3b sgRNA-2 PX459 plasmid

    Plasmid

    #192250

    Purpose

    expressing sgRNA-2 targeting eIF3b locus closed to stop coden

    Depositor

    Dieter Wolf

    Article

    Duan et al EMBO J. 2023 Jun 15;42(12):e112362. doi:

    Insert

    sgRNA-2 targeting eIF3b locus closed to stop coden (EIF3B Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Jan. 4, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Lenti-sgCol11a1#2/Cre

    Plasmid

    #193206

    Purpose

    Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Col11a1 gene

    Depositor

    Julien Sage

    Article

    Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

    Insert

    sgCol11a1#2 (Col11a1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. Lenti-sgGrin2a#1/Cre

    Plasmid

    #193217

    Purpose

    Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Grin2a gene

    Depositor

    Julien Sage

    Article

    Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

    Insert

    sgGrin2a#1 (Grin2a Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pcDNA-EGFP MASTL E167D (siRNA resistant)

    Plasmid

    #191013

    Purpose

    Expresses EGFP-tagged MASTL with E167D mutation and resistance to MASTL siRNA (ACGCCTTATTCTAGCAAATTA)

    Depositor

    Johanna Ivaska

    Article

    Taskinen et al J Cell Biol. 2020 Jun 1;219(6). pii: 151

    Insert

    Microtubule-associated serine/threonine kinase like (MASTL Human)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    E167D

    Promoter

    Available since

    Nov. 15, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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