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pHR-SFFV- MOG-VHVL-M38-synNotch-Gal4VP64

Plasmid

#247502

Purpose

Expresses a synNotch binding to myelin oligodendrocyte glycoprotein

Depositor

Wendell Lim

Article

Simic et al Science. 2024 Dec 6;386(6726):eadl4237.

Insert

synNotch receptor using a scFvs binding to MOG

Use

Lentiviral

Expression

Mammalian

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pHR_PGK_ anti-NRCAM 12955 (VL + VH) synNotch

Plasmid

#247511

Purpose

Expresses a synNotch binding to NrCAM (neural cell adhesion molecule)

Depositor

Wendell Lim

Article

Simic et al Science. 2024 Dec 6;386(6726):eadl4237.

Insert

Expresses a synNotch binding to NrCAM (neural cell adhesion molecule)

Use

Lentiviral

Expression

Mammalian

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pHR_PGK_ anti-PTPRZ CA-FNIII domain 13062 (VL+VH) synNotch

Plasmid

#247521

Purpose

Expresses a synNotch receptor binding to PTPRZ

Depositor

Wendell Lim

Article

Simic et al Science. 2024 Dec 6;386(6726):eadl4237.

Insert

Expresses a synNotch receptor binding to PTPRZ

Use

Lentiviral

Expression

Mammalian

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pHR Gal4-UAS_3XFlag_4D5-5_CAR-mCherry_pGK_BFP

Plasmid

#247572

Purpose

GAL4/UAS expression of a CAR against HER2 and mCherry with constitutive BFP

Depositor

Wendell Lim

Article

Simic et al Science. 2024 Dec 6;386(6726):eadl4237.

Insert

GAL4/UAS expression of a CAR against HER2 - mCherry and BFP constitutive

Use

Lentiviral

Expression

Mammalian

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pUltra-EGFP-P2A-Tr-NRL

Plasmid

#239100

Purpose

pUltra-EGFP bi-cistronic lentiviral vector expressing EGFP and truncated NRL.

Depositor

David Cobrinik

Article

Shayler et al eLife 13:RP101918

Insert

Neural Retina Leucine Zipper (truncated) (NRL Human)

Use

Lentiviral

Available Since

Sept. 17, 2025

Availability

Academic Institutions and Nonprofits only

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pVKS-1

Plasmid

#233086

Purpose

HNRNPD full-length promoter reporter construct

Depositor

Shyam Chauhan

Article

Kumar et al Sci Rep. 2022 Apr 8;12(1):5944. doi: 10.

Insert

HNRNPD (HNRNPD, AUF1 Human)

Use

Luciferase

Promoter

HNRNPD Promoter

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA4-C-EF1α-Tr-NRL

Plasmid

#239096

Purpose

Expresses truncated NRL, driven by EF1α promoter.

Depositor

David Cobrinik

Article

Shayler et al eLife 13:RP101918

Insert

Neural Retina Leucine Zipper (truncated) (NRL Human)

Expression

Mammalian

Available Since

Sept. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA4-C-EF1α-FL-NRL

Plasmid

#239095

Purpose

Expresses full length NRL, driven by EF1α promoter.

Depositor

David Cobrinik

Article

Shayler et al eLife 13:RP101918

Insert

Neural Retina Leucine Zipper (NRL Human)

Expression

Mammalian

Available Since

Sept. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pk335-CARGO-11mer-35kb-DSF-1-11

Plasmid

#227489

Purpose

11-mer gRNA array targeting Sp dCas9/Cas9 to the Prdm8-Fgf5 locus

Depositor

Joanna Wysocka

Article

Jensen et al Mol Cell. 2025 Jan 16;85(2):347-361.e7.

Insert

CARGO to 35kb Downstream Fgf5

Use

CRISPR

Available Since

May 5, 2025

Availability

Academic Institutions and Nonprofits only

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pk335-CARGO-12mer-14kb-USF-1-12

Plasmid

#227472

Purpose

12-mer gRNA array targeting Sp dCas9/Cas9 to the Prdm8-Fgf5 locus

Depositor

Joanna Wysocka

Article

Jensen et al Mol Cell. 2025 Jan 16;85(2):347-361.e7.

Insert

CARGO to 14kb Upstream Fgf5

Use

CRISPR

Available Since

May 5, 2025

Availability

Academic Institutions and Nonprofits only

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sg_Snrnp48_i1-ipUSEPR-TR657

Plasmid

#228925

Purpose

Knockdown of Snrnp48 in mammalian cells

Depositor

Sika Zheng

Article

Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

Insert

sg_Snrnp48_i1 (Snrnp48 Mouse)

Use

Lentiviral

Available Since

April 16, 2025

Availability

Academic Institutions and Nonprofits only

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rag2:RAB3IP_CE_pISceI

Plasmid

#223044

Purpose

Express RAB3IP gene in mesenchymal lineage of Zebrafish.

Depositor

Alejandro Gutierrez

Article

Ali et al Mol Cell. 2025 Mar 6;85(5):948-961.e11.

Insert

RAB3IP (RAB3IP Human)

Use

Express the insert(gene) in mesenchymal lineage o…

Promoter

Rag2

Available Since

Feb. 24, 2025

Availability

Academic Institutions and Nonprofits only

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rag2:WDR4_CE_pISceI

Plasmid

#223051

Purpose

Express WDR4 gene in mesenchymal lineage of Zebrafish.

Depositor

Alejandro Gutierrez

Article

Ali et al Mol Cell. 2025 Mar 6;85(5):948-961.e11.

Insert

WDR4 (WDR4 Human)

Use

Express the insert(gene) in mesenchymal lineage o…

Promoter

Rag2

Available Since

Feb. 24, 2025

Availability

Academic Institutions and Nonprofits only

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rag2:TSFM_CE_pISceI

Plasmid

#223031

Purpose

Express TSFM gene in mesenchymal lineage of Zebrafish.

Depositor

Alejandro Gutierrez

Article

Ali et al Mol Cell. 2025 Mar 6;85(5):948-961.e11.

Insert

TSFM (TSFM Human)

Use

Express the insert(gene) in mesenchymal lineage o…

Promoter

Rag2

Available Since

Feb. 24, 2025

Availability

Academic Institutions and Nonprofits only

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rag2:OS9_CE_pISceI

Plasmid

#223023

Purpose

Express OS9 gene in mesenchymal lineage of Zebrafish.

Depositor

Alejandro Gutierrez

Article

Ali et al Mol Cell. 2025 Mar 6;85(5):948-961.e11.

Insert

OS9 (OS9 Human)

Use

Express the insert(gene) in mesenchymal lineage o…

Promoter

Rag2

Available Since

Feb. 24, 2025

Availability

Academic Institutions and Nonprofits only

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rag2:TSPAN31_CE_pISceI

Plasmid

#223025

Purpose

Express TSPAN31 gene in mesenchymal lineage of Zebrafish.

Depositor

Alejandro Gutierrez

Article

Ali et al Mol Cell. 2025 Mar 6;85(5):948-961.e11.

Insert

TSPAN31 (TSPAN31 Human)

Use

Express the insert(gene) in mesenchymal lineage o…

Promoter

Rag2

Available Since

Feb. 24, 2025

Availability

Academic Institutions and Nonprofits only

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Str-KDEL_SBP-EGFP-CCR5-Cys3A

Plasmid

#222313

Purpose

Synchronize the trafficking of CCR5-Cys3A from the ER.

Depositor

Franck Perez

Article

Boncompain et al Sci Adv. 2019 Oct 16;5(10):eaax0821. doi

Insert

Streptavidin-KDEL and CCR5-Cys3A fused to SBP-EGFP (CCR5 Human)

Expression

Mammalian

Mutation

C321A, C323A, C324A

Promoter

CMV

Available Since

Feb. 4, 2025

Availability

Academic Institutions and Nonprofits only

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sg_Tada3_i3-ipUSEPR-TR657

Plasmid

#228915

Purpose

Knockdown of Tada3 in mammalian cells

Depositor

Sika Zheng

Article

Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

Insert

sg_Tada3_i3 (Tada3 Mouse)

Use

Lentiviral

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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sg_Tada3_i5-ipUSEPR-TR657

Plasmid

#228916

Purpose

Knockdown of Tada3 in mammalian cells

Depositor

Sika Zheng

Article

Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

Insert

sg_Tada3_i3 (Tada3 Mouse)

Use

Lentiviral

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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sg_Atm_i3-ipUSEPR-TR657

Plasmid

#228917

Purpose

Knockdown of Atm in mammalian cells

Depositor

Sika Zheng

Article

Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

Insert

sg_Atm_i3 (Atm Mouse)

Use

Lentiviral

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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