We narrowed to 16,263 results for: grn

1. lentiCRISPR - Amplicon, JAK2 sgRNA 2

   Plasmid

   #70660

   Purpose

   Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and an intergenic JAK2 amplicon-targeting sgRNA element from U6 promoter. Lentiviral backbone

   Depositor

   David Sabatini

   Article

   Wang et al Science. 2015 Oct 15. pii: aac7041.

   Insert

   sgRNA against JAK2 amplicon found in AML-derived HEL cell line (JAK2 )
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Oct. 29, 2015

   Availability

   Academic Institutions and Nonprofits only

2. pAN-PBAD-sgRNA-A2T

   Plasmid

   #62258

   Purpose

   expression of A2T sgRNA from the arabinose-inducible promoter

   Depositor

   Christopher Voigt

   Article

   Nielsen et al Mol Syst Biol. 2014 Nov 24;10:763. doi:

   Insert

   A2T sgRNA
   

   Use

   CRISPR

   Expression

   Bacterial

   Promoter

   pBAD

   Available Since

   April 8, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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3. Cas9 ROSA sgRNA mCherry

   Plasmid

   #155280

   Purpose

   Lentiviral Cas9 expression, ROSA sgRNA expression, mCherry marker

   Depositor

   Martin Carroll

   Insert

   spCas9
   

   Available Since

   Aug. 31, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. AAV_3xgRNA;PTENA, p53B,SMAD4A_CAG_FlPO_synthPA

   Plasmid

   #68346

   Purpose

   Used to produce AAV expressing the FlpO recombinase and pig gRNA towards 3 tumor suppressors: PTEN, p53 and SMAD4

   Depositor

   Jannik Elverløv-Jakobsen

   Article

   Berthelsen et al Cancers (Basel). 2021 Jun 16;13(12). pii

   Inserts

   3xgRNA;PTENA, p53B,SMAD4A
   FlPO
   

   Use

   AAV; Flp/frt

   Expression

   Mammalian

   Promoter

   CAG and U6

   Available Since

   Dec. 2, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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5. px335-sgRNA-EF(Cas9n)-Eif4a1-L

   Plasmid

   #122346

   Purpose

   Expresses sgRNA targeting mouse Eif4a1 and Cas9 nickase in mammalian cells

   Depositor

   Hiroshi Ochiai

   Article

   Ochiai et al Sci Adv. 2020 Jun 17;6(25):eaaz6699. doi

   Insert

   sgRNA for mouse Eif4a1
   

   Expression

   Mammalian

   Available Since

   June 30, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCF820_U6-sgRNA-EF1a-mCherry2_lenti

   Plasmid

   #138316

   Purpose

   Lenti expression of mCherry2 with U6 promoter for SpyCas9 sgRNA targeting GFP

   Depositor

   Jennifer Doudna

   Article

   Watters et al Proc Natl Acad Sci U S A. 2020 Mar 10. p

   Insert

   SpyCas9 GFP sgRNA
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   March 23, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAN-PBAD-sgRNA-A1T

   Plasmid

   #62256

   Purpose

   expression of A1T sgRNA from the arabinose-inducible promoter

   Depositor

   Christopher Voigt

   Article

   Nielsen et al Mol Syst Biol. 2014 Nov 24;10:763. doi:

   Insert

   A1T sgRNA
   

   Use

   CRISPR

   Expression

   Bacterial

   Promoter

   pBAD

   Available Since

   April 8, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAN-PBAD-sgRNA-A4NT

   Plasmid

   #62261

   Purpose

   expression of A4NT sgRNA from the arabinose-inducible promoter

   Depositor

   Christopher Voigt

   Article

   Nielsen et al Mol Syst Biol. 2014 Nov 24;10:763. doi:

   Insert

   A4NT sgRNA
   

   Use

   CRISPR

   Expression

   Bacterial

   Promoter

   pBAD

   Available Since

   April 8, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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9. Icam 2 SaCas9 YAP sgRNA3

   Plasmid

   #99736

   Purpose

   Expresses SaCas9 and a gRNA targeting mouse YAP

   Depositor

   Yu Huang

   Article

   Wang et al Nature. 2016 Dec 7. doi: 10.1038/nature2

   Insert

   SaCas9 gRNA targeting Yap1 (Yap1 Mouse)
   

   Use

   AAV and CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Dec. 11, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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10. 1184_pAAV-U6-ApoB-gRNA2-CB-EmGFP

    Plasmid

    #89062

    Purpose

    AAV-gRNA targeting the murine Apob gene

    Depositor

    William Lagor

    Article

    Jarrett et al Sci Rep. 2017 Mar 16;7:44624. doi: 10.10

    Insert

    EmGFP
    

    Use

    AAV and CRISPR

    Expression

    Mammalian

    Promoter

    Chicken beta actin with partial CMV enhancer

    Available Since

    April 11, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAAV-SMVP-Cas9N-U6-gRNA M4

    Plasmid

    #80937

    Purpose

    Expresses Cas9N in mammalian cells; expresses gRNA M4 for Mstn cleavage.

    Depositor

    George Church

    Article

    Chew et al Nat Methods. 2016 Sep 5. doi: 10.1038/nm

    Insert

    Cas9N
    

    Use

    AAV, CRISPR, and Synthetic Biology

    Expression

    Mammalian

    Available Since

    Oct. 3, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLKO1-puro-U6-sgRNA-LRTM2

    Plasmid

    #69237

    Purpose

    U6 driven SpCas9 sgRNA expression for LRTM2 site

    Depositor

    Scot Wolfe

    Article

    Bolukbasi et al Nat Methods. 2015 Oct 19. doi: 10.1038/n

    Insert

    LRTM2 sgRNA (LRTM2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Oct. 20, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAN-PBAD-sgRNA-A3T

    Plasmid

    #62260

    Purpose

    expression of A3T sgRNA from the arabinose-inducible promoter

    Depositor

    Christopher Voigt

    Article

    Nielsen et al Mol Syst Biol. 2014 Nov 24;10:763. doi:

    Insert

    A3T sgRNA
    

    Use

    CRISPR

    Expression

    Bacterial

    Promoter

    pBAD

    Available Since

    April 8, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAN-PBAD-sgRNA-A3NT

    Plasmid

    #62259

    Purpose

    expression of A3NT sgRNA from the arabinose-inducible promoter

    Depositor

    Christopher Voigt

    Article

    Nielsen et al Mol Syst Biol. 2014 Nov 24;10:763. doi:

    Insert

    A3NT sgRNA
    

    Use

    CRISPR

    Expression

    Bacterial

    Promoter

    pBAD

    Available Since

    April 8, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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15. pSS2.1-Cas9-HH-gRNADhps-HDV

    Plasmid

    #241015

    Purpose

    Cas9 expression cassette encoding a guide RNA targeting the Dhps locus, flanked by a hammerhead (HH) ribozyme at the 5′ end and a hepatitis delta virus (HDV) ribozyme at the 3′ end

    Depositor

    Alan Smulian

    Article

    Sayson et al mBio. 2025 Sep 23:e0182525. doi: 10.1128

    Inserts

    Cas9-Hammerhead (HH) Ribozyme-gRNA(Dhps)-Hepatitis Delta Virus (HDV) Ribozyme
    blasticidin-S deaminase
    

    Expression

    Yeast

    Available Since

    Nov. 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. phU6-LaTranC-mini-sgRNA

    Plasmid

    #246934

    Purpose

    for HEK293T human cell genome editing

    Depositor

    Caixia Gao

    Article

    Jin et al Cell. 2025 Sep 29:S0092-8674(25)01035-9.

    Insert

    LaTranC mini-sgRNA
    

    Use

    CRISPR

    Available Since

    Oct. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pYJ39-PB-CRISPR-NKX3.1-E2-gRNA2

    Plasmid

    #131082

    Purpose

    NKX3-1 knock out

    Depositor

    Xiaojun Lian

    Insert

    NKX3.1 Exon2 gRNA2 (NKX3-1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pYJ40-PB-CRISPR-NKX3.1-E2-gRNA3

    Plasmid

    #131083

    Purpose

    NKX3-1 knock out

    Depositor

    Xiaojun Lian

    Insert

    NKX3.1 Exon2 gRNA3 (NKX3-1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pYJ36-PB-CRISPR-NKX3.1-E1-gRNA1

    Plasmid

    #131079

    Purpose

    NKX3-1 knock out

    Depositor

    Xiaojun Lian

    Insert

    NKX3.1 Exon1 gRNA1 (NKX3-1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pYJ37-PB-CRISPR-NKX3.1-E1-gRNA2

    Plasmid

    #131080

    Purpose

    NKX3-1 knock out

    Depositor

    Xiaojun Lian

    Insert

    NKX3.1 Exon1 gRNA2 (NKX3-1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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