We narrowed to 10,414 results for: 158

1. pACT-HAB1_star

   Plasmid

   #241277

   Purpose

   Orthogonal PYR1/HAB1 sensor module

   Depositor

   Sean Cutler

   Article

   Park et al Nat Chem Biol. 2024 Jan;20(1):103-110. d

   Insert

   HAB1_star (HAB1 Mustard Weed)
   

   Use

   Tags

   Expression

   Yeast

   Mutation

   NA

   Promoter

   Available since

   Aug. 25, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pLentiRNACRISPR_011-TetO-NLS-inactive-RfxCas13d-NLS-WPRE-EFS-rtTA3-2A-Blast

   Plasmid

   #228557

   Purpose

   Expresses inactive RfxCas13d in mammalian cells for binding of target RNAs in combination with compatible crRNAs. Localized to the nucleus

   Depositor

   Neville Sanjana

   Article

   Hart et al Nat Biotechnol. 2025 Feb 11. doi: 10.103

   Insert

   dRfxCas13d
   

   Use

   Lentiviral

   Tags

   NLS-HA

   Expression

   Mutation

   R239A/H244A/R858A/H863A

   Promoter

   Available since

   Aug. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pJRoC30-LacAnc100

   Plasmid

   #234653

   Purpose

   Expresses LacAnc100 variant in yeast

   Depositor

   Miguel Alcalde Galeote, Alice Ting

   Article

   Lee et al Nat Chem Biol. 2025 Aug 1. doi: 10.1038/

   Insert

   LacAnc100
   

   Use

   Tags

   HRV 3C protease site-GSG linker-8xHis tag

   Expression

   Yeast

   Mutation

   Promoter

   Gal1p

   Available since

   Aug. 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pCMV-Flag-hGSDME

   Plasmid

   #218939

   Purpose

   Expression of N-terminal FLAG tagged human gasdermin E

   Depositor

   Christopher LaRock

   Article

   LaRock et al Nature. 2022 May;605(7910):527-531. doi:

   Insert

   human GSDME (GSDME Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   July 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pCMV-Flag-hGSDMA

   Plasmid

   #218935

   Purpose

   Expression of N-terminal FLAG tagged human gasdermin A

   Depositor

   Christopher LaRock

   Article

   LaRock et al Nature. 2022 May;605(7910):527-531. doi:

   Insert

   human GSDMA (GSDMA Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   July 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. FUS LC 8Y->S

   Plasmid

   #226606

   Purpose

   8 tyrosines to serine

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC 8Y->S (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   8 tyrosines to serine

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pcDNA3.1-HaloAKAR2.1-CLC

   Plasmid

   #216492

   Purpose

   Expression of chemigenetic PKA biosensor (medium basal brightness, high dynamic range) targeted to clathrin coated pits

   Depositor

   Jin Zhang

   Article

   Frei et al Nat Biotechnol. 2025 Apr 21. doi: 10.103

   Insert

   HaloAKAR2.1-CLC
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   June 20, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pGEMHE-Trim21-OLLAS

   Plasmid

   #237438

   Purpose

   Expresses mouse Trim21 ubiquitin ligase tagged with OLLAS at C-term; made for in vitro transcription (T7 promoter)

   Depositor

   Michael Lampson

   Article

   Dudka et al Nature. 2025 Feb;638(8051):814-822. doi:

   Insert

   Trim21 (Trim21 Mouse)
   

   Use

   Tags

   OLLAS

   Expression

   Mammalian

   Mutation

   Promoter

   T7

   Available since

   June 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pRCA376 - pBA904 Puro-T2A-GFP NTC guide (pRCA360 backbone)

   Plasmid

   #238167

   Purpose

   Lentiviral CRISPR guide vector expressing a non-targeting sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture

   Depositor

   Thomas Norman

   Article

   Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415

   Insert

   Non-targeting sgRNA
   

   Use

   CRISPR and Lentiviral

   Tags

   GFP

   Expression

   Mutation

   Promoter

   Available since

   June 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pHAGE Flag HA ADAR2

    Plasmid

    #237856

    Purpose

    Lentiviral expression of ADAR2

    Depositor

    David Pellman

    Article

    Tang et al Nature. 2022 Jun;606(7916):930-936. doi:

    Insert

    ADAR2 (ADARB1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pLIX401 C-term SETX

    Plasmid

    #237999

    Purpose

    Inducible lentiviral expression of C-term SETX

    Depositor

    David Pellman

    Article

    Tang et al Nature. 2022 Jun;606(7916):930-936. doi:

    Insert

    SETX (SETX Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. XZ390 (IVT) CMV-TO-T7-mCherry-SGc(stem-1(3xMS2))cSG-rTetR-NZF-NLS-hybridUTR3

    Plasmid

    #233425

    Purpose

    IVT template for LIDAR reporter mRNA; mCherry as marker, rtetR-NZF as output

    Depositor

    Xiaojing Gao

    Article

    Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

    Insert

    T7-mCherry-SGc(stem-1(3xMS2))cSG-rTetR-NZF-NLS-hybridUTR3
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    CMV

    Available since

    April 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pAAV_hSyn_NES-Kinprola_on-mEGFP_WRPE-SV40

    Plasmid

    #233368

    Purpose

    hSyn1 driven expression of the consitutively active kinase activity recorder positive control Kinprola_on fused to mEGFP for neuronal expression through AAV transduction

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_on-mEGFP
    

    Use

    AAV

    Tags

    NES and mEGFP

    Expression

    Mutation

    Promoter

    hSyn1

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pAAV_hSyn_NES-Kinprola_PKA_T/A-mEGFP_WRPE-SV40

    Plasmid

    #233367

    Purpose

    hSyn1 driven expression of the inactive PKA activity recorder negative control with T/A mutation Kinprola_PKA fused to mEGFP for neuronal expression through AAV transduction

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_PKA_T/A-mEGFP
    

    Use

    AAV

    Tags

    NES and mEGFP

    Expression

    Mutation

    Promoter

    hSyn1

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pCDNA5/FRT_CMV_NES-Kinprola_off-mEGFP

    Plasmid

    #233356

    Purpose

    CMV driven expression of the inactive kinase activity recorder negative control Kinprola_off in mammalian cell lines fused to mEGFP

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_off-mEGFP
    

    Use

    Tags

    NES and mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pCDNA5/FRT_CMV_NES-Kinprola_PKA_T/A-mEGFP

    Plasmid

    #233354

    Purpose

    CMV driven expression of the inactive PKA activity recorder negative control with T/A mutation Kinprola_PKA_T/A in mammalian cell lines fused to mEGFP

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_PKA_T/A-mEGFP
    

    Use

    Tags

    NES and mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pCDNA5/FRT_CMV_NES-Kinprola_JNK_T/A-mEGFP

    Plasmid

    #233360

    Purpose

    CMV driven expression of the inactive JNK activity recorder negative control with T/A mutation Kinprola_JNK_T/A in mammalian cell lines fused to mEGFP

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_JNK_T/A-mEGFP
    

    Use

    Tags

    NES and mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pCDNA5/FRT_CMV_NES-Kinprola_PKC_T/A-mEGFP

    Plasmid

    #233358

    Purpose

    CMV driven expression of the inactive PKC activity recorder negative control with T/A mutation Kinprola_PKC_T/A in mammalian cell lines fused to mEGFP

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_PKC_T/A-mEGFP
    

    Use

    Tags

    NES and mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pCDNA5/FRT_CMV_NES-Kinprola_on-mEGFP

    Plasmid

    #233355

    Purpose

    CMV driven expression of the consitutively active kinase activity recorder positive control Kinprola_on in mammalian cell lines fused to mEGFP

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_on-mEGFP
    

    Use

    Tags

    NES and mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pCDNA5/FRT_CMV_NES-Kinprola_AMPK_T/A-mEGFP

    Plasmid

    #233362

    Purpose

    CMV driven expression of the inactive AMPK activity recorder negative control with T/A mutation Kinprola_AMPK_T/A in mammalian cell lines fused to mEGFP

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_AMPK_T/A-mEGFP
    

    Use

    Tags

    NES and mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pLKO.1-puro_CMV_NES-Kinprola_on-mEGFP

    Plasmid

    #233370

    Purpose

    CMV driven expression of the consitutively active kinase activity recorder positive control Kinprola_on fused to mEGFP for neuronal expression through lentivirus transduction

    Depositor

    Kai Johnsson

    Article

    Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

    Insert

    NES-Kinprola_on-mEGFP
    

    Use

    Lentiviral

    Tags

    NES and mEGFP

    Expression

    Mutation

    Promoter

    CMV

    Available since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pscAAV.CAG-EGFP-SV40pA-T7-T3-BC(p1-14)

    Plasmid

    #231346

    Purpose

    Self complementary AAV genome with components for tracking self-complementary AAV genomes via AAV-Zombie. Also expresses EGFP from CAG promoter.

    Depositor

    Viviana Gradinaru

    Article

    Coughlin et al Nat Biotechnol. 2025 Mar 20. doi: 10.103

    Insert

    T7/T3-BC(p1-14)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pscAAV.BC(p1-6)-CAG-EGFP-SV40pA-BC(p1-6)

    Plasmid

    #231349

    Purpose

    Self complementary AAV genome with concatemerization-dependent barcodes, for tracking AAV concatemers via SpECTr. Also expresses EGFP from CAG promoter.

    Depositor

    Viviana Gradinaru

    Article

    Coughlin et al Nat Biotechnol. 2025 Mar 20. doi: 10.103

    Insert

    BC(p1-10)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. p25.pA.NGFR.mCMV.hPGK.Rab35(WT).wpre[sequenced]

    Plasmid

    #226764

    Purpose

    rab35 (WT)

    Depositor

    Ferdinando Pucci

    Article

    Ziglari et al Cancer Res. 2025 Mar 3;85(5):859-874. do

    Insert

    rab35 (RAB35 )
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. CA-0034 CMVTO-hIL6-rens-hIL6Ra_M4

    Plasmid

    #231217

    Purpose

    C-CageIL-6

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    hIL6-rens-hIL6Ra_M4 (IL6 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    A228D, N230D, H280S, D281V

    Promoter

    Available since

    Jan. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. CA-0200 CMVTO-hIL6Ra_M4-rens-hIL6

    Plasmid

    #231193

    Purpose

    CageIL-6 (N-term)

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    hIL6Ra_M4-rens-hIL6 (IL6 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    A228D, N230D, H280S, D281V

    Promoter

    Available since

    Jan. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. CA-0057 CMVTO-SumIL2-rens-2GS-IL2Rb

    Plasmid

    #231222

    Purpose

    CageIL-2 (C-term 10 AA)

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    SumIL2-rens-2GS-IL2Rb (IL2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    L80F, R81D, L85V, I86V, I92F

    Promoter

    Available since

    Jan. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. CA-0046 CMVTO-hIL10dimer-rens-IL10Ra

    Plasmid

    #231188

    Purpose

    Fused cageIL-10-dimer

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    hIL10dimer-rens-IL10Ra (IL10 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. CA-0062 CMVTO-SumIL2-3GS-rens-IL2Rb

    Plasmid

    #231220

    Purpose

    CageIL-2 (N-term 15 AA)

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    SumIL2-3GS-rens-IL2Rb (IL2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    L80F, R81D, L85V, I86V, I92F

    Promoter

    Available since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. CA-0064 CMVTO-SumIL2-noGS-rens-IL2Rb

    Plasmid

    #231218

    Purpose

    CageIL-2 (N-term 0 AA)

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    SumIL2-noGS-rens-IL2Rb (IL2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    L80F, R81D, L85V, I86V, I92F

    Promoter

    Available since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge