We narrowed to 16,259 results for: GRN

1. pX458_mCherry-NPM1-gRNA for U2OS

   Plasmid

   #238250

   Purpose

   Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to NPM1 locus

   Depositor

   Denes Hnisz

   Article

   Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

   Insert

   NPM1
   

   Use

   CRISPR

   Available Since

   June 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. hSyn-HA-PGRN-IRES2-GFP

   Plasmid

   #234876

   Purpose

   Lentiviral plasmid expressing HA-tagged human progranulin followed by IRES2-GFP.

   Depositor

   Andrew Arrant

   Article

   Davis et al J Biol Chem. 2021 Sep;297(3):100993. doi

   Insert

   Progranulin (GRN Human)
   

   Use

   Lentiviral

   Tags

   HA tag

   Expression

   Mammalian

   Promoter

   hSYn

   Available Since

   April 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. lentiGuide-chr20-49345720-gRNA1

   Plasmid

   #232623

   Purpose

   Lentiviral plasmid expressing gRNA targeting the enhancer region in Chr20:49345720 (hg38) locus with lentiGuide-Hygro-eGFP (Addgene #99375) as backbone.

   Depositor

   Claes Wadelius

   Article

   Christensen et al Eur Heart J. 2025 Apr 10:ehaf213. doi: 1

   Insert

   S. pyogenes sgRNA cassette
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   April 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. lentiGuide-chr20-49345720-gRNA2

   Plasmid

   #232624

   Purpose

   Lentiviral plasmid expressing gRNA targeting the enhancer region in Chr20:49345720 (hg38) locus with lentiGuide-Hygro-eGFP (Addgene #99375) as backbone.

   Depositor

   Claes Wadelius

   Article

   Christensen et al Eur Heart J. 2025 Apr 10:ehaf213. doi: 1

   Insert

   S. pyogenes sgRNA cassette
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   April 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. lentiGuide-chr20-49345720-gRNA3

   Plasmid

   #232625

   Purpose

   Lentiviral plasmid expressing gRNA targeting the enhancer region in Chr20:49345720 (hg38) locus with lentiGuide-Hygro-eGFP (Addgene #99375) as backbone.

   Depositor

   Claes Wadelius

   Article

   Christensen et al Eur Heart J. 2025 Apr 10:ehaf213. doi: 1

   Insert

   S. pyogenes sgRNA cassette
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   April 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLentiCRISPR V2 Neo PTEN sgRNA5

   Plasmid

   #233246

   Purpose

   Knock out of murine PTEN

   Depositor

   David Bryant

   Article

   Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

   Insert

   PTEN (Pten Mouse)
   

   Use

   Lentiviral

   Available Since

   March 20, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLentiCRISPR V2 Neo PTEN sgRNA2

   Plasmid

   #233245

   Purpose

   Knock out of murine PTEN

   Depositor

   David Bryant

   Article

   Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

   Insert

   PTEN (Pten Mouse)
   

   Use

   Lentiviral

   Available Since

   March 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. esgRNA_NbATML1-2pro and NbATML1-1pro

   Plasmid

   #231155

   Purpose

   T-DNA encoding TRV2 with mobile gRNAs targeting NbATML1-2pro and NbATML1-1pro

   Depositor

   Daniel Voytas

   Article

   Liu et al Plant Physiol. 2024 Mar 29;194(4):2229-2

   Insert

   mobile gRNAs targeting NbATML1-2pro and NbATML1-1pro
   

   Expression

   Plant

   Promoter

   PEBV sub-genomic

   Available Since

   Jan. 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLentiCRISPR v2 puro mGSDME gRNA2

   Plasmid

   #223522

   Purpose

   Knocking out mGSDME in mouse cells

   Depositor

   Judy Lieberman

   Article

   Zhang et al Nature. 2020 Mar;579(7799):415-420. doi:

   Insert

   GSDME (GSDME Mouse)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Jan. 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLentiCRISPR v2 puro mGSDME gRNA1

    Plasmid

    #223521

    Purpose

    Knocking out mGSDME in mouse cells

    Depositor

    Judy Lieberman

    Article

    Zhang et al Nature. 2020 Mar;579(7799):415-420. doi:

    Insert

    GSDME (GSDME Mouse)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Jan. 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pM148: pAAV.CMV-Cas13e-NT sgRNA

    Plasmid

    #203446

    Purpose

    Plasmid expressing active RfxCas13d with non-targeting gRNA

    Depositor

    Guei-Sheung Liu

    Article

    Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

    Inserts

    U6-non targeting (NT) sgRNA
    Cas13e
    

    Use

    AAV

    Tags

    HA and NLS

    Expression

    Mammalian

    Promoter

    CMV and U6

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCAG-3xGFP11-mem-3xPax7gRNA

    Plasmid

    #224571

    Purpose

    Ubiquitous expression plasmid with CAG promoter (CMV immediate early enhancer, chicken beta actin promoter), three unique Pax7 gRNAs with ribozyme self-cleavage, three membrane split GFP(11) reporter.

    Depositor

    Erica Hutchins

    Article

    Kim et al Dev Biol. 2024 Nov 30:S0012-1606(24)0026

    Insert

    3xGFP11
    

    Use

    CRISPR

    Tags

    Membrane Localization Signal

    Mutation

    Codon optimized

    Available Since

    Dec. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pTBL3428 MTK234-LacO-BtoApegRNA

    Plasmid

    #226669

    Purpose

    MTK234 part containing lac-inducible variant of the hU6 promoter driving a B to A pegRNA

    Depositor

    Chang Liu

    Article

    Loveless et al bioRxiv 2021.11.05.467507

    Insert

    hU6-LacOS-BtoApegRNA
    

    Use

    CRISPR and Synthetic Biology

    Expression

    Mammalian

    Promoter

    hU6-LacOS

    Available Since

    Nov. 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pTBL3331 MTK234-TetO-AtoBpegRNA

    Plasmid

    #226668

    Purpose

    MTK234 part containing tet-inducible variant of the hU6 promoter driving an A to B pegRNA

    Depositor

    Chang Liu

    Article

    Loveless et al bioRxiv 2021.11.05.467507

    Insert

    hU6-TetO-AtoBpegRNA
    

    Use

    CRISPR and Synthetic Biology

    Expression

    Mammalian

    Promoter

    hU6-TetO

    Available Since

    Nov. 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pGL3-Ctr1-gRNA-EGFP

    Plasmid

    #226000

    Purpose

    Negative control for CRISPRi-KD

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    negtive control sgRNA of no specific targets in human genome
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGL3-Ctr2-gRNA-EGFP

    Plasmid

    #226001

    Purpose

    Negative control for CRISPRi-KD

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    negtive control sgRNA of no specific targets in human genome
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pGL3-hL1-gRNA1-EGFP

    Plasmid

    #226002

    Purpose

    CRISPRi-KD of human LINE1

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    sgRNA targeting human L1HS
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pGL3-hL1-gRNA2-EGFP

    Plasmid

    #226003

    Purpose

    CRISPRi-KD of human LINE1

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    sgRNA targeting human L1HS
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pGL3-NCL-gRNA1-EGFP

    Plasmid

    #226004

    Purpose

    CRISPRi-KD of human Nucleolin

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    sgRNA targeting human Nucleolin (NCL Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pGL3-NCL-gRNA2-EGFP

    Plasmid

    #226005

    Purpose

    CRISPRi-KD of human Nucleolin

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    sgRNA targeting human Nucleolin (NCL Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge