We narrowed to 14,924 results for: TIM

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ICK gRNA (BRDN0001146903)

Plasmid

#77414

Purpose

3rd generation lentiviral gRNA plasmid targeting human ICK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ICK

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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P21-sp64 Poly A

Plasmid

#59433

Purpose

synthetic poly A transcripts of VZV

Depositor

Randall Cohrs

Article

Cohrs et al J Virol. 2000 Dec;74(24):11464-71.

Insert

VZV ORF 21

Use

Makes synthetic transcripts that contains poly a

Tags

none

Mutation

none

Promoter

SP6

Available Since

Sept. 2, 2014

Availability

Academic Institutions and Nonprofits only
SH3BP4 gRNA (BRDN0001149529)

Plasmid

#78087

Purpose

3rd generation lentiviral gRNA plasmid targeting human SH3BP4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SH3BP4 (SH3BP4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SH3BP4 gRNA (BRDN0001487091)

Plasmid

#78089

Purpose

3rd generation lentiviral gRNA plasmid targeting human SH3BP4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SH3BP4 (SH3BP4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pTA-M+

Plasmid

#249818

Purpose

Expresses Mycobacterium tuberculosis topoisomerase I under the control of the Tet promoter in mycobacteria

Depositor

Yuk-Ching Tse-Dinh

Article

Sandhaus et al Antimicrob Agents Chemother. 2016 Jun 20

Insert

Mycobacterium tuberculosis topoisomerase I (topA Mycobacterium tuberculosis)

Tags

6xHis

Expression

Bacterial

Promoter

Tet

Available Since

March 9, 2026

Availability

Academic Institutions and Nonprofits only

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NSE-huCof K22Q-mRFP

Plasmid

#252618

Purpose

Neuronal specific expression of a mRFP tagged human cofilin K22Q (rod reporter)

Depositor

James Bamburg

Article

Mi et al PLoS One. 2013 Dec 31;8(12):e83609. doi:

Insert

cofilin 1 (CFL1 Human)

Tags

mRFP

Expression

Mammalian

Promoter

Neuronal Specific Enolase (NSE)

Available Since

March 6, 2026

Availability

Industry, Academic Institutions, and Nonprofits

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pMDC32B-BS-AtMIR390a-A18G-B/c

Plasmid

#246716

Purpose

Cloning amiRNA sequences in AtMIR390a-A18G precursors for in planta expression

Depositor

Alberto Carbonell

Article

Llorens-Gamez et al Plant J. 2026 Jan;125(1):e70665. doi: 10

Insert

Basal stem of Arabidopsis MIR390a precursor with A18G mutation & chloramphenicol-ccdB cassette flanked by two BsaI sites (MIR390a Mustard Weed)

Use

RNAi

Expression

Plant

Available Since

Jan. 14, 2026

Availability

Academic Institutions and Nonprofits only

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M3-dCAS9-DNMT3A-DNMT3A (dCas9-3A-3A)

Plasmid

#218776

Purpose

Expresses dCAS9-DNMT3A-DNMT3A fusion protein and double marker GFP-T2A-Puro under independent promoters

Depositor

Maja Jagodic

Article

Kakhki et al bioRxiv 2025.03.15.641804; doi: 10.1101/

Inserts

M3-dCAS9-DNMT3A-DNMT3A (dCas9-3A-3A)
GFP-T2A-Puro

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 13, 2026

Availability

Academic Institutions and Nonprofits only

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M3-dCAS9-DNMT3A-KRAB (dCas9-3A-KRAB)

Plasmid

#218781

Purpose

Expresses dCAS9-DNMT3A-KRAB fusion protein and double marker GFP-T2A-Puro under independent promoters

Depositor

Maja Jagodic

Article

Kakhki et al bioRxiv 2025.03.15.641804; doi: 10.1101/

Inserts

M3-dCAS9-DNMT3A-DNMT3L (dCas9-3A-3L)
GFP-T2A-Puro

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 13, 2026

Availability

Academic Institutions and Nonprofits only

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M3-dCAS9-M.SssI (dCas9-M.SssI)

Plasmid

#218782

Purpose

Expresses dCAS9-M.SssI fusion protein and double marker GFP-T2A-Puro under independent promoters

Depositor

Maja Jagodic

Article

Kakhki et al bioRxiv 2025.03.15.641804; doi: 10.1101/

Inserts

M3-dCAS9-M.SssI (dCas9-M.SssI)
GFP-T2A-Puro

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 13, 2026

Availability

Academic Institutions and Nonprofits only

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M3-dCAS9-dDNMT3A (dCas9-d3A)

Plasmid

#218787

Purpose

Expresses dCAS9-dead DNMT3A fusion protein and double marker GFP-T2A-Puro under independent promoters

Depositor

Maja Jagodic

Article

Kakhki et al bioRxiv 2025.03.15.641804; doi: 10.1101/

Inserts

M3-dCAS9-dDNMT3A (dCas9-d3A)
GFP-T2A-Puro

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 13, 2026

Availability

Academic Institutions and Nonprofits only

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M3-dCAS9-mutDNMT3A(R882H)(dCas9-mut3A)

Plasmid

#218788

Purpose

Expresses dCAS9- R882H Mutated DNMT3A fusion protein and double marker GFP-T2A-Puro under independent promoters

Depositor

Maja Jagodic

Article

Kakhki et al bioRxiv 2025.03.15.641804; doi: 10.1101/

Inserts

M3-dCAS9-MutDNMT3A (dCas9-Mut3A (R882H))
GFP-T2A-Puro

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 13, 2026

Availability

Academic Institutions and Nonprofits only

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pLentiX1-CAG-mRuby2-HRAS(G12V)

Plasmid

#244165

Purpose

Lentiviral expression of mRuby2-HRAS(G12V)

Depositor

Kate Galloway

Article

Lende-Dorn et al Cell Rep. 2025 Sep 23;44(9):116226. doi:

Insert

mRuby2-HRAS(G12V) (HRAS Human)

Use

Lentiviral

Expression

Mammalian

Mutation

G12V

Available Since

Jan. 9, 2026

Availability

Academic Institutions and Nonprofits only

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pMXs-9SA.mNgn2-x3HA

Plasmid

#244167

Purpose

Retroviral expression of phospho-mutant mouse Ngn2 with HA tag

Depositor

Kate Galloway

Article

Lende-Dorn et al Cell Rep. 2025 Sep 23;44(9):116226. doi:

Insert

mNgn2 (phospho mutant) (Neurog2 Mouse)

Use

Retroviral

Tags

x3HA

Expression

Mammalian

Mutation

S24A, S66A, S192A, S203A, S205A, S215A, S224A, S2…

Available Since

Jan. 9, 2026

Availability

Academic Institutions and Nonprofits only

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VN627 pAC-cI_E34P-Asf1B_Term_f1-pOL2-62_L_eGFP-KanR

Plasmid

#235103

Purpose

Quantitative bacterial two-hybrid (qB2H). Expresses Asf1B.

Depositor

Oscar Ramos

Article

Guyot et al bioRxiv 2025.10.29.680610

Insert

Asf1B (ASF1B Human)

Use

Synthetic Biology; Quantitative bacterial two-hyb…

Tags

cI_E34P

Expression

Bacterial

Promoter

lacUV5

Available Since

Oct. 27, 2025

Availability

Academic Institutions and Nonprofits only

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VN999 pB2Hws_v9_cI-Asf1B+rpoA-IP3mut3A

Plasmid

#235104

Purpose

Quantitative bacterial two-hybrid (qB2H). Expresses Asf1B and IP3mut3A.

Depositor

Oscar Ramos

Article

Guyot et al bioRxiv 2025.10.29.680610

Inserts

Asf1B (ASF1B Human)
IP3mut3A

Use

Synthetic Biology; Quantitative bacterial two-hyb…

Tags

cI_E34P-rpoA

Expression

Bacterial

Promoter

lacUV5 and lpp+lacUV5

Available Since

Oct. 27, 2025

Availability

Academic Institutions and Nonprofits only

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pSG5-CAGEc-PRKACA (Nrdj1)

Plasmid

#241421

Purpose

Proximity-triggered Protein Trans-Splicing to generate the splice product DNAJ-PKAc, Figure 4, Extended Figure 8-9 in Nature Chemical Biology 20.10 (2024): 1353-1360.

Depositor

Thomas Muir

Article

Lee et al Nat Chem Biol. 2024 Oct;20(10):1353-1360

Insert

CAGEc-PRKACA (Nrdj1) (PRKACA Synthetic, Human)

Tags

HA

Expression

Mammalian

Promoter

SV40

Available Since

Oct. 7, 2025

Availability

Academic Institutions and Nonprofits only

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pME-DRE-nls (JDW 31)

Plasmid

#242561

Purpose

Gateway middle entry clone containing Dre recombinase

Depositor

Joshua Wythe

Article

Gillespie WB et al Development. 2025 Nov 15;152(22):dev2043

Insert

codon optimized DRE-nls

Use

Gateway subcloning

Available Since

Sept. 22, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-G12-AkaLuc-P2A-Proinsulin

Plasmid

#241776

Purpose

Tested on HeLa for bioluminescence, and used for production of AAV G12-Akaluc-P2A-Proinsulin for mice.

Depositor

Vladislav Verkhusha

Article

Kasatkina et al Nat Commun. 2025 Jul 14;16(1):6469. doi:

Insert

AkaLuc-P2A-Proinsulin

Use

AAV

Promoter

12xUAS with TATA-box minimal promoter

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1-NES-CAGEc-HOXA9c (Nrdj1)

Plasmid

#241416

Purpose

Proximity-triggered Protein Trans-Splicing to generate the splice product MLL-AF9, Figure 2 & Extended Figure 4 in Nature Chemical Biology 20.10 (2024): 1353-1360.

Depositor

Thomas Muir

Article

Lee et al Nat Chem Biol. 2024 Oct;20(10):1353-1360

Insert

NES-CAGEc-HOXA9c (Nrdj1) (HOXA9 Synthetic, Human)

Tags

3xFLAG and HA

Expression

Mammalian

Promoter

CMV

Available Since

Sept. 8, 2025

Availability

Academic Institutions and Nonprofits only

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