We narrowed to 55,956 results for: STI;

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pLCV2-CDK12(hU6-sg2-mU6-sg3)-Blast

Plasmid

#208344

Purpose

pLentiCRISPRv2-Blast backbone with two separate sgRNAs against CDK12

Depositor

Peter S Nelson

Article

Frank et al eLife 2025

Insert

cyclin dependent kinase 12 (CDK12 Human)

Use

CRISPR and Lentiviral

Promoter

hU6, mU6

Available Since

Jan. 29, 2026

Availability

Academic Institutions and Nonprofits only

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pLCV2-CDK13(hU6-sg2-mU6-sg3)-Blast

Plasmid

#208348

Purpose

pLentiCRISPRv2-Blast backbone with two separate sgRNAs against CDK13

Depositor

Peter S Nelson

Article

Frank et al eLife 2025

Insert

cyclin dependent kinase 13 (CDK13 Human)

Use

CRISPR and Lentiviral

Promoter

hU6, mU6

Available Since

Jan. 29, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
pLCV2-CDK12(hU6-sg2-mU6-sg3)-Blast

Plasmid

#208344

Purpose

pLentiCRISPRv2-Blast backbone with two separate sgRNAs against CDK12

Depositor

Peter S Nelson

Article

Frank et al eLife 2025

Insert

cyclin dependent kinase 12 (CDK12 Human)

Use

CRISPR and Lentiviral

Promoter

hU6, mU6

Available Since

Jan. 29, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
pLCV2-CDK13(hU6-sg2-mU6-sg3)-Blast

Plasmid

#208348

Purpose

pLentiCRISPRv2-Blast backbone with two separate sgRNAs against CDK13

Depositor

Peter S Nelson

Article

Frank et al eLife 2025

Insert

cyclin dependent kinase 13 (CDK13 Human)

Use

CRISPR and Lentiviral

Promoter

hU6, mU6

Available Since

Jan. 29, 2026

Availability

Academic Institutions and Nonprofits only

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MB 94C thsS(t3)R-Bxb1_P7-sfGFP_mCherry

Plasmid

#232471

Purpose

Optimized thiosulfate sensor with recombinase switch and fluorescent reporter (GFP), constitutive mCherry

Depositor

Mikhail Shapiro

Article

Buss et al Nat Commun. 2025 Aug 25;16(1):7931. doi:

Inserts

thsS(t3)
thsR
PphsA342
sfGFP
AxeTxe
mCherry
Bxb1 integrase

Tags

ssrA degradation tag

Expression

Bacterial

Mutation

Contains the following mutations K286Q, Q350H, I…

Promoter

J23100 (TTGACGGCTAGCTCAGTCCTAGGTACAGTGCTAGC), J23…

Available Since

Sept. 17, 2025

Availability

Academic Institutions and Nonprofits only

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MB 94C thsS(t3)R-Bxb1_P7-sfGFP_mCherry

Plasmid

#232471

Purpose

Optimized thiosulfate sensor with recombinase switch and fluorescent reporter (GFP), constitutive mCherry

Depositor

Mikhail Shapiro

Article

Buss et al Nat Commun. 2025 Aug 25;16(1):7931. doi:

Inserts

thsS(t3)
thsR
PphsA342
sfGFP
AxeTxe
mCherry
Bxb1 integrase

Tags

ssrA degradation tag

Expression

Bacterial

Mutation

Contains the following mutations K286Q, Q350H, I…

Promoter

J23100 (TTGACGGCTAGCTCAGTCCTAGGTACAGTGCTAGC), J23…

Available Since

Sept. 17, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
Click editor utilizing mSA for template recruitment and ePhi29 DNA polymerase - pCMV-T7-mSA-nCas9-ePhi29 (JO1398)

Plasmid

#217803

Purpose

Variant CE1 construct with mSA for template recruitment and ePhi29(D169A) DNA pol, expressed from CMV or T7 promoters.

Depositor

Benjamin Kleinstiver

Article

Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

Insert

mSA-linker-SV40NLS-nSpCas9-BPNLS-ePhi29-BPNLS

Use

CRISPR; In vitro transcription; t7 promoter

Tags

BPNLS

Expression

Mammalian

Mutation

nSpCas9(H840A); Phi29(D169A/M8R/V51A/M97T/G197D/E…

Promoter

CMV and T7

Available Since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

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Unfused click editor construct; mSA-ePhi29 - pCMV-T7-mSA-Phi29 (JO1411)

Plasmid

#217807

Purpose

Unfused click editor construct expressing mSA-ePhi29(D169A), expressed from CMV or T7 promoters.

Depositor

Benjamin Kleinstiver

Article

Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

Insert

mSA-linker-SV40NLS-ePhi29-BPNLS

Use

CRISPR; In vitro transcription; t7 promoter

Tags

BPNLS

Expression

Mammalian

Mutation

Phi29(D169A/M8R/V51A/M97T/G197D/E221K/Q497P/K512E…

Promoter

CMV and T7

Available Since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
Click editor utilizing mSA for template recruitment and ePhi29 DNA polymerase - pCMV-T7-mSA-nCas9-ePhi29 (JO1398)

Plasmid

#217803

Purpose

Variant CE1 construct with mSA for template recruitment and ePhi29(D169A) DNA pol, expressed from CMV or T7 promoters.

Depositor

Benjamin Kleinstiver

Article

Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

Insert

mSA-linker-SV40NLS-nSpCas9-BPNLS-ePhi29-BPNLS

Use

CRISPR; In vitro transcription; t7 promoter

Tags

BPNLS

Expression

Mammalian

Mutation

nSpCas9(H840A); Phi29(D169A/M8R/V51A/M97T/G197D/E…

Promoter

CMV and T7

Available Since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
Unfused click editor construct; mSA-ePhi29 - pCMV-T7-mSA-Phi29 (JO1411)

Plasmid

#217807

Purpose

Unfused click editor construct expressing mSA-ePhi29(D169A), expressed from CMV or T7 promoters.

Depositor

Benjamin Kleinstiver

Article

Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

Insert

mSA-linker-SV40NLS-ePhi29-BPNLS

Use

CRISPR; In vitro transcription; t7 promoter

Tags

BPNLS

Expression

Mammalian

Mutation

Phi29(D169A/M8R/V51A/M97T/G197D/E221K/Q497P/K512E…

Promoter

CMV and T7

Available Since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
Click editor utilizing Cdc13 for template recruitment - pCMV-T7-Cdc13-nCas9-EcKlenow (JO1293)

Plasmid

#217796

Purpose

Variant CE1 construct with Cdc13 telomere binding protein for template recruitment, expressed from CMV or T7 promoters.

Depositor

Benjamin Kleinstiver

Article

Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

Insert

Cdc13-XTEN-nSpCas9-BPNLS-EcKlenow(-exo)-BPNLS

Use

CRISPR; In vitro transcription; t7 promoter

Tags

BPNLS

Expression

Mammalian

Mutation

nSpCas9(H840A); EcKlenow(-exo;D355A/E357A)

Promoter

CMV and T7

Available Since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
Click editor utilizing Cdc13(Y556A) for template recruitment - pCMV-T7-Cdc13(Y556A)-nCas9-EcKlenow (JO1329)

Plasmid

#217797

Purpose

Variant CE1 construct with Cdc13(Y556A) telomere binding protein for template recruitment, expressed from CMV or T7 promoters.

Depositor

Benjamin Kleinstiver

Article

Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

Insert

Cdc13(Y556A)-XTEN-nSpCas9-BPNLS-EcKlenow(-exo)-BPNLS

Use

CRISPR; In vitro transcription; t7 promoter

Tags

BPNLS

Expression

Mammalian

Mutation

Cdc13(Y556A); nSpCas9(H840A); EcKlenow(-exo;D355A…

Promoter

CMV and T7

Available Since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
Click editor utilizing Cdc13 for template recruitment - pCMV-T7-Cdc13-nCas9-EcKlenow (JO1293)

Plasmid

#217796

Purpose

Variant CE1 construct with Cdc13 telomere binding protein for template recruitment, expressed from CMV or T7 promoters.

Depositor

Benjamin Kleinstiver

Article

Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

Insert

Cdc13-XTEN-nSpCas9-BPNLS-EcKlenow(-exo)-BPNLS

Use

CRISPR; In vitro transcription; t7 promoter

Tags

BPNLS

Expression

Mammalian

Mutation

nSpCas9(H840A); EcKlenow(-exo;D355A/E357A)

Promoter

CMV and T7

Available Since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
Click editor utilizing Cdc13(Y556A) for template recruitment - pCMV-T7-Cdc13(Y556A)-nCas9-EcKlenow (JO1329)

Plasmid

#217797

Purpose

Variant CE1 construct with Cdc13(Y556A) telomere binding protein for template recruitment, expressed from CMV or T7 promoters.

Depositor

Benjamin Kleinstiver

Article

Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

Insert

Cdc13(Y556A)-XTEN-nSpCas9-BPNLS-EcKlenow(-exo)-BPNLS

Use

CRISPR; In vitro transcription; t7 promoter

Tags

BPNLS

Expression

Mammalian

Mutation

Cdc13(Y556A); nSpCas9(H840A); EcKlenow(-exo;D355A…

Promoter

CMV and T7

Available Since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pMXS-IRES-BLAST flag-CAD delta Allosteric Domain

Plasmid

#169835

Purpose

Expresses C-terminal flag-tagged CAD with substitution of allosteric domain F1308 - C1455 with a (GGGS)X3 linker

Depositor

Richard Possemato

Article

Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

Insert

CAD (CAD Human)

Use

Retroviral

Tags

Flag tag

Expression

Mammalian

Mutation

Substitution of amino acids F1308 - C1455 with a …

Available Since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pMXS-IRES-BLAST flag-CAD delta Allosteric Domain

Plasmid

#169835

Purpose

Expresses C-terminal flag-tagged CAD with substitution of allosteric domain F1308 - C1455 with a (GGGS)X3 linker

Depositor

Richard Possemato

Article

Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

Insert

CAD (CAD Human)

Use

Retroviral

Tags

Flag tag

Expression

Mammalian

Mutation

Substitution of amino acids F1308 - C1455 with a …

Available Since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
shTRIP13-2-seed

Plasmid

#184535

Purpose

shRNA expression vector

Depositor

Andrew Hong

Article

Mittal et al Commun Biol. 2024 Apr 8;7(1):426. doi: 1

Insert

TRIP13 (TRIP13 Human)

Use

RNAi

Expression

Mammalian

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
shTRIP13-1

Plasmid

#184536

Purpose

shRNA expression vector

Depositor

Andrew Hong

Article

Mittal et al Commun Biol. 2024 Apr 8;7(1):426. doi: 1

Insert

TRIP13 (TRIP13 Human)

Use

RNAi

Expression

Mammalian

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
shTRIP13-2

Plasmid

#184537

Purpose

shRNA expression vector

Depositor

Andrew Hong

Article

Mittal et al Commun Biol. 2024 Apr 8;7(1):426. doi: 1

Insert

TRIP13 (TRIP13 Human)

Use

RNAi

Expression

Mammalian

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
shTRIP13-2-seed

Plasmid

#184535

Purpose

shRNA expression vector

Depositor

Andrew Hong

Article

Mittal et al Commun Biol. 2024 Apr 8;7(1):426. doi: 1

Insert

TRIP13 (TRIP13 Human)

Use

RNAi

Expression

Mammalian

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge