We narrowed to 1,786 results for: mcp

1. pLX209-neo-WRN K577M

   Plasmid

   #125790

   Purpose

   constitutive, ectopic expression of a helicase-dead mutant of human WRN (K577M)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   myc-WRN K577M (WRN Human)
   

   Tags

   5x myc

   Expression

   Mammalian

   Mutation

   K577M (helicase-dead)

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLX209-neo-WRN E84A

   Plasmid

   #125789

   Purpose

   constitutive, ectopic expression of an exonuclease-dead mutant of human WRN (E84A)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   myc-WRN E84A (WRN Human)
   

   Tags

   5x myc

   Expression

   Mammalian

   Mutation

   E84A (exonuclease-dead)

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLX209-neo-WRN E84A K577M

   Plasmid

   #125791

   Purpose

   constitutive, ectopic expression of an endonuclease/helicase-dead mutant of human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   myc-WRN E84A/K577M (WRN Human)
   

   Tags

   5x myc

   Expression

   Mammalian

   Mutation

   E84A/K577M (exonuclease/helicase-dead)

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pXPR_BRD051-sgMLH1-1

   Plasmid

   #125776

   Purpose

   constitutive expression of a guide RNA targeting human MLH1 (CRISPR cutting control) and S. pyogenes Cas9

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgMLH1-1 (MLH1 Human)
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pXPR_BRD051-sgMLH1-2

   Plasmid

   #125777

   Purpose

   constitutive expression of a guide RNA targeting human MLH1 (CRISPR cutting control) and S. pyogenes Cas9

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgMLH1-2 (MLH1 Human)
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pXPR_BRD003-sgWRN-EIJ

   Plasmid

   #125774

   Purpose

   constitutive expression of a guide RNA targeting an exon-intron junction of human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgWRN-EIJ (WRN Human)
   

   Use

   CRISPR

   Available Since

   June 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pXPR_BRD003-sgPOLR2D

   Plasmid

   #125769

   Purpose

   constitutive expression of a guide RNA targeting human POLR2D (CRISPR positive control)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgPOLR2D (POLR2D Human)
   

   Use

   CRISPR

   Available Since

   May 29, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pXPR_BRD003-sgMYC

   Plasmid

   #125770

   Purpose

   constitutive expression of a guide RNA targeting human MYC (CRISPR positive control)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgMYC (MYC Human)
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. MSCV-N MCV LT FL

   Plasmid

   #37862

   Depositor

   Karl Munger

   Article

   Rozenblatt-Rosen et al Nature. 2012 Jul 26;487(7408):491-5.

   Insert

   MCV LT FL (MCPyV_gp1 Human Merkel Cell Virus)
   

   Use

   Retroviral

   Tags

   Flag and HA

   Expression

   Mammalian

   Promoter

   PKG

   Available Since

   July 23, 2012

   Availability

   Academic Institutions and Nonprofits only

10. pRcCMV Cep215 (Nigg CW493)

    Plasmid

    #41152

    Depositor

    Erich Nigg

    Article

    Graser et al J Cell Sci. 2007 Dec 15;120(Pt 24):4321-

    Insert

    Cep215 (CDK5RAP2 Human)
    

    Tags

    Myc

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    June 7, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA6 MCV LTco S220A

    Plasmid

    #112193

    Purpose

    Expression of MCPyV LT mutant (Ser 220 to Ala)

    Depositor

    Patrick Moore

    Article

    Kwun et al Proc Natl Acad Sci U S A. 2017 May 16;11

    Insert

    MCPyV LT codon optimized
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Sept. 19, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. pGEX4T-HEPN

    Plasmid

    #75296

    Purpose

    Expresses Sacsin HEPN domain (4441-4579) in fusion with GST (bacterial)

    Depositor

    Kalle Gehring

    Article

    Kozlov et al J Biol Chem. 2011 Jun 10;286(23):20407-1

    Insert

    Human Sacsin 4441-4579
    

    Tags

    GST-Tag

    Expression

    Bacterial

    Available Since

    July 18, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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13. pWaldo-GFPe_PepTSo

    Plasmid

    #58334

    Purpose

    Expresses the POT family transporter from Shewanella oniedensis in E. coli as a C-terminally tagged GFP his tagged protein

    Depositor

    Simon Newstead, So Iwata

    Article

    Newstead et al EMBO J. 2011 Jan 19;30(2):417-26. doi: 1

    Insert

    PepTso
    

    Tags

    GFP-His

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    Oct. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

14. pcDNA6 MCV LTco S239A

    Plasmid

    #112194

    Purpose

    Expression of MCPyV LT mutant (Ser 239 to Ala)

    Depositor

    Patrick Moore

    Article

    Kwun et al Proc Natl Acad Sci U S A. 2017 May 16;11

    Insert

    MCPyV LT codon optimized
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Sept. 19, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. pcDNA6 MCV LTco S147A

    Plasmid

    #112192

    Purpose

    Expression of MCPyV LT mutant (Ser 147 to Ala)

    Depositor

    Patrick Moore

    Article

    Kwun et al Proc Natl Acad Sci U S A. 2017 May 16;11

    Insert

    MCPyV LT codon optimized
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 11, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGEX6P1-Ubl

    Plasmid

    #78712

    Purpose

    Expresses Sacsin Ubl- domain (2-85) in fusion with GST (bacterial)

    Depositor

    Kalle Gehring

    Article

    Menade et al J Biol Chem. 2018 Aug 17;293(33):12832-1

    Insert

    Human Sacsin 2-85
    

    Tags

    GST-Tag

    Expression

    Bacterial

    Available Since

    July 19, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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17. pGEX6P1-sr1(SIRPT1)

    Plasmid

    #75297

    Purpose

    Expresses Sacsin sr1 (SIRPT1 repeat) domain (84-339) in fusion with GST (bacterial)

    Depositor

    Kalle Gehring

    Article

    Menade et al J Biol Chem. 2018 Aug 17;293(33):12832-1

    Insert

    Human Sacsin 84-339
    

    Tags

    GST-Tag

    Expression

    Bacterial

    Available Since

    July 18, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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18. pGEX6P1-Ubl-sr1(SIRPT1)

    Plasmid

    #75298

    Purpose

    Expresses Sacsin Ubl-sr1 (SIRPT1 repeat) domain (1-339) in fusion with GST (bacterial)

    Depositor

    Kalle Gehring

    Article

    Menade et al J Biol Chem. 2018 Aug 17;293(33):12832-1

    Insert

    Human Sacsin 1-339
    

    Tags

    GST-Tag

    Expression

    Bacterial

    Available Since

    July 18, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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19. HS-DN-Cep152-mKate2

    Plasmid

    #105943

    Purpose

    heat shock inducible transgenesis

    Depositor

    Caren Norden

    Article

    Strzyz et al Dev Cell. 2015 Jan 26;32(2):203-19. doi:

    Insert

    Cep152 (CEP152 Human)
    

    Tags

    mKate2

    Expression

    Bacterial

    Mutation

    dominant negative (AA 1-512)

    Available Since

    Feb. 6, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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20. pCMV5-hBMPR-1A CA

    Plasmid

    #49527

    Purpose

    expresses constitutively active human BMP receptor 1A

    Depositor

    Lee Niswander, Peter ten Dijke

    Article

    Varley et al Dev Biol. 1998 Apr 1;196(1):107-18.

    Insert

    BMPR-1A CA (BMPR1A Human)
    

    Expression

    Mammalian

    Mutation

    constitutively active mutation (Q233D); also P2A …

    Promoter

    CMV

    Available Since

    May 20, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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