We narrowed to 24,150 results for: Spr

1. pFRT/TO/GFP-SCAF8 (CRISPR_resistant)

   Plasmid

   #122472

   Purpose

   Dox-inducible GFP (N-terminal tag) SCAF8 expression

   Depositor

   Jesper Svejstrup

   Article

   Gregersen et al Cell. 2019 May 10. pii: S0092-8674(19)30

   Insert

   SCAF8 (SCAF8 Human)
   

   Use

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   Synonymous mutations conferring resistance to gRN…

   Promoter

   CMV

   Available since

   May 16, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. CASPR/Neurexin IV scFv [K65/35]

   Plasmid

   #182068

   Purpose

   Mammalian Expression of CASPR/Neurexin IV scFv. Derived from hybridoma K65/35.

   Depositor

   James Trimmer

   Article

   Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

   Insert

   recombinant mouse scFv targeting CASPR/Neurexin IV (Rattus norvegicus) (Cntnap1 Mouse)
   

   Use

   Tags

   Sortase, His

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   March 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCDNA3-Flag-SPRTN-Y117C

   Plasmid

   #110216

   Purpose

   Expression in mammalian cells of of full-length SPRTN protein carrying Y117C mutation, a catalytically-impaired mutant, and Flag-tag at N-terminus.

   Depositor

   Kristijan Ramadan, Ivana Marinovic-Terzic

   Article

   Vaz et al Mol Cell. 2016 Nov 17;64(4):704-719. doi

   Insert

   SPRTN (SPRTN Human)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Y117C, P296L (see depositor comments below)

   Promoter

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. Non-targeting CRISPRi plasmid

   Plasmid

   #154891

   Purpose

   Human non-targeting CRISPRi gRNA

   Depositor

   Rob Mitra, Joseph Dougherty

   Article

   Lalli et al Genome Res. 2020 Sep;30(9):1317-1331. do

   Insert

   Nontargeting gRNA
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Nov. 18, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. lentiCRISPR - Amplicon, JAK2 sgRNA 1

   Plasmid

   #70679

   Purpose

   Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and an intergenic JAK2 amplicon-targeting sgRNA element from U6 promoter. Lentiviral backbone

   Depositor

   David Sabatini

   Article

   Wang et al Science. 2015 Oct 15. pii: aac7041.

   Insert

   sgRNA against JAK2 amplicon found in AML-derived HEL cell line (JAK2 )
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 29, 2015

   Availability

   Academic Institutions and Nonprofits only

6. LentiCRISPR v2-sgAMPK alpha1 clone3

   Plasmid

   #162121

   Purpose

   Lentiviral sgRNA plasmid targeting human AMPK alpha1

   Depositor

   Boyi Gan

   Article

   Lee et al Nat Cell Biol. 2020 Feb;22(2):225-234. d

   Insert

   sgAMPK alpha1 (PRKAA1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Jan. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pBW1997_pExpr-hU6-CRISPR-DECODER

   Plasmid

   #87549

   Purpose

   Expresses NGN2, MIAT, ACTC1, and TTN gRNAs in response to combinations of Cre and Flp recombinases

   Depositor

   Wilson Wong

   Article

   Weinberg et al Nat Biotechnol. 2017 Mar 27. doi: 10.103

   Insert

   gRNAs targeting NGN2, MIAT, ACTC1, TTN
   

   Use

   CRISPR, Cre/Lox, and Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. lentiCRISPR - Amplicon, JAK2 sgRNA 2

   Plasmid

   #70660

   Purpose

   Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and an intergenic JAK2 amplicon-targeting sgRNA element from U6 promoter. Lentiviral backbone

   Depositor

   David Sabatini

   Article

   Wang et al Science. 2015 Oct 15. pii: aac7041.

   Insert

   sgRNA against JAK2 amplicon found in AML-derived HEL cell line (JAK2 )
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 29, 2015

   Availability

   Academic Institutions and Nonprofits only

9. LentiCRISPR-B_2xsgRNAs_UPF3A/UPF3B (pAVA3129)

   Plasmid

   #239329

   Purpose

   Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting UPF3A and UPF3B

   Depositor

   Andrei Alexandrov

   Article

   Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

   Insert

   U6-driven sgRNA1 targting UPF3A and 7SK-driven sgRNA2 targeting UPF3B (UPF3B Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Aug. 4, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. LentiCRISPR-B_sgRNA-RMP64 (pAVA3500)

    Plasmid

    #239237

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RMP64

    Depositor

    Andrei Alexandrov

    Article

    Che et al Cell Rep. 2025 Jun 24;44(6):115752. doi:

    Insert

    U6-driven sgRNA targeting RMP64
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. LentiCRISPR-B_sgRNA-RMP24 (pAVA3547)

    Plasmid

    #239240

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RMP24

    Depositor

    Andrei Alexandrov

    Article

    Che et al Cell Rep. 2025 Jun 24;44(6):115752. doi:

    Insert

    U6-driven sgRNA targeting RMP24
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. LentiCRISPR-B_sgRNA-RMP24 (pAVA3555)

    Plasmid

    #239242

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RMP24

    Depositor

    Andrei Alexandrov

    Article

    Che et al Cell Rep. 2025 Jun 24;44(6):115752. doi:

    Insert

    U6-driven sgRNA targeting RMP24
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. LentiCRISPR-B_sgRNA-RMP24 (pAVA3563)

    Plasmid

    #239258

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RMP24

    Depositor

    Andrei Alexandrov

    Article

    Che et al Cell Rep. 2025 Jun 24;44(6):115752. doi:

    Insert

    U6-driven sgRNA targeting RMP24
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. LentiCRISPR-B_sgRNA-RMP64 (pAVA3572)

    Plasmid

    #239259

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RMP64

    Depositor

    Andrei Alexandrov

    Article

    Che et al Cell Rep. 2025 Jun 24;44(6):115752. doi:

    Insert

    U6-driven sgRNA targeting RMP64
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. LentiCRISPR-B_2xsgRNAs-RMRP (pAVA3583)

    Plasmid

    #239260

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting RMRP

    Depositor

    Andrei Alexandrov

    Article

    Che et al Cell Rep. 2025 Jun 24;44(6):115752. doi:

    Insert

    U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting RMRP
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. LentiCRISPR-B_2xsgRNAs-RMRP (pAVA3584)

    Plasmid

    #239261

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting RMRP

    Depositor

    Andrei Alexandrov

    Article

    Che et al Cell Rep. 2025 Jun 24;44(6):115752. doi:

    Insert

    U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting RMRP
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. LentiCRISPR-B_2xsgRNAs-RPPH1 (pAVA3585)

    Plasmid

    #239262

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting RPPH1

    Depositor

    Andrei Alexandrov

    Article

    Che et al Cell Rep. 2025 Jun 24;44(6):115752. doi:

    Insert

    U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting RPPH1
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. lentiCRISPRv2-Merlin(dog)gRNA1

    Plasmid

    #214823

    Purpose

    A knockout vector for dog Merlin.

    Depositor

    Michiyuki Matsuda

    Article

    Jikko et al J Cell Sci. 2025 Jul 16:jcs.263779. doi:

    Insert

    A gRNA targeting the dog NF2(Merlin) gene and the cDNA of CRISPR-Cas9
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. SpRY-Tad-CBE(CCG3)

    Plasmid

    #235083

    Purpose

    Expresses SpRY-Tad-CBE(CCG3) in mammalian cells.

    Depositor

    Weixin Tang

    Article

    Wu et al Nat Biotechnol. 2025 Jul 7:10.1038/s4158

    Insert

    Tad-CBE(CCG3)-SpRY Cas9 D10A
    

    Use

    CRISPR

    Tags

    2xUGI, bpNLS and bpNLS

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. SpRY-Tad-CBE(ACC2)

    Plasmid

    #235081

    Purpose

    Expresses SpRY-Tad-CBE(ACC2) in mammalian cells.

    Depositor

    Weixin Tang

    Article

    Wu et al Nat Biotechnol. 2025 Jul 7:10.1038/s4158

    Insert

    Tad-CBE(ACC2)-SpRY Cas9 D10A
    

    Use

    CRISPR

    Tags

    2xUGI, bpNLS and bpNLS

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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