We narrowed to 23,295 results for: c-MYC

1. pcDNA3.1-GSDMD_1-275

   Plasmid

   #218230

   Purpose

   Gasdermin-D_1-275 is a pore-forming GSDMD formed by cleavage by host caspases. Transfection in HEK293 cells showed GSDMD 1-275 pores secrete 3CLpro, nucleocapsid; in excess, kills cells by pyroptosis

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD (GSDMD Human)
   

   Use

   Tags

   flag

   Expression

   Mammalian

   Mutation

   construct only codes for amino acids 1-275

   Promoter

   Available Since

   July 1, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. pcDNA3.1-GSDMD_29-484

   Plasmid

   #218231

   Purpose

   Gasdermin-D_29-484 is a non-functional GSDMD formed by SARS-CoV-2 3CLpro cleavage in the N-terminal domain. Transfection in HEK293 cells showed no pore-forming activity or induction of pyroptosis

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD (GSDMD Human)
   

   Use

   Tags

   flag

   Expression

   Mammalian

   Mutation

   construct only codes for amino acids 29-484

   Promoter

   Available Since

   July 1, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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3. pcDNA3.1-GSDMD_29-270

   Plasmid

   #218232

   Purpose

   Gasdermin-D_29-270 is a non-functional GSDMD formed by two SARS-CoV-2 3CLpro cleavages. Transfection in HEK293 cells showed no pore-forming activity or induction of pyroptosis

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD (GSDMD Human)
   

   Use

   Tags

   flag

   Expression

   Mammalian

   Mutation

   construct only codes for amino acids 29-270

   Promoter

   Available Since

   July 1, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

4. pLV-PB2_Lock1-I436C+S993C

   Plasmid

   #182879

   Purpose

   Lentivirus for expression of Plexin-B2 locked ring mutant

   Depositor

   Roland Friedel

   Article

   Junqueira Alves et al Nat Commun. 2025 Jan 2;16(1):272. doi: 1

   Insert

   hPLXNB2 (PLXNB2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   changed Isoleucine 436 to Cysteine and Serine 993…

   Promoter

   Available Since

   Jan. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLV-PB2_Lock2-I436C+T1051C

   Plasmid

   #182880

   Purpose

   Lentivirus for expression of Plexin-B2 locked ring mutant

   Depositor

   Roland Friedel

   Article

   Junqueira Alves et al Nat Commun. 2025 Jan 2;16(1):272. doi: 1

   Insert

   hPLXNB2 (PLXNB2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   changed Isoleucine 436 to Cysteine and Threonine …

   Promoter

   Available Since

   Jan. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pEF2-EFGR-hTyro

   Plasmid

   #225998

   Purpose

   Expresses a chimeric construct having N-terminal human EGFR and C-terminal human Tyro3

   Depositor

   Sergei Kotenko, Raymond Birge

   Article

   Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

   Insert

   human EGFR N-Terminal human Tyro3 C-Terminal Fusion (EGFR, TYRO3 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1-a

   Available Since

   Nov. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. JDW 832 (pDONR221-V5-mTagBFP2-KRAS4A-G12D)

   Plasmid

   #156404

   Purpose

   Gateway middle entry clone encoding V5-tagged mTagBFP2-fused to human KRAS4A with G12D mutation, includes a stop codon

   Depositor

   Joshua Wythe

   Article

   Fish et al Circ Res. 2020 Jun 17. doi: 10.1161/CIRC

   Insert

   human mutant KRAS4A-G12D (KRAS Human)
   

   Use

   Gateway cloning

   Tags

   mTagBFP2

   Expression

   Mutation

   mutant KRAS4A-G12D

   Promoter

   Available Since

   Aug. 18, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pMT646 human L1 ORF2p-3xFlag (ORFeus-Hs, CMV promoter) in pCEP4 Puro

   Plasmid

   #213026

   Purpose

   Expresses full length human LINE-1 in human cells (codon optimized ORFeus-Hs), with a C-terminal 3xFlag tag on ORF2

   Depositor

   Martin S. Taylor

   Article

   Baldwin et al Nature. 2024 Feb;626(7997):194-206. doi:

   Insert

   Human LINE-1 (ORFeus-Hs codon optimized sequence) with ORF2-3xFlag
   

   Use

   Tags

   3xFlag (ORF2p)

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available Since

   May 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLD564 human L1 ORF2p-3xFlag (L1RP, CMV promoter) in pCEP4 Puro

   Plasmid

   #213030

   Purpose

   Expresses full length human LINE-1 in human cells (native L1RP sequence), with a C-terminal 3xFlag tag on ORF2

   Depositor

   Martin S. Taylor

   Article

   Baldwin et al Nature. 2024 Feb;626(7997):194-206. doi:

   Insert

   Human LINE-1 (L1RP Sequence) with 5' UTR and ORF2-3xFlag
   

   Use

   Tags

   3xFlag (ORF2p)

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available Since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. CMV-LUC2CP/intron/ARE

    Plasmid

    #62858

    Purpose

    splicing reporter (with intron) with elements to shorten the half-life of the luciferase protein as well as the luciferase mRNA.

    Depositor

    Gideon Dreyfuss

    Article

    Younis et al Mol Cell Biol. 2010 Apr;30(7):1718-28. d

    Insert

    Luciferase
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    insertion of chimeric intron at nueotide poclsiti…

    Promoter

    CMV

    Available Since

    April 3, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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