We narrowed to 508 results for: SYN1

1. pAAV-Syn1-fDIO-mScarlet-KASH-2a-dCre

   Plasmid

   #203839

   Purpose

   Flp-dependent enzymatically inactive Cre and mScarlet-KASH expression

   Depositor

   Ivo Spiegel

   Article

   Roethler et al Neuron. 2023 Jun 20:S0896-6273(23)00399-

   Insert

   dCre
   

   Use

   AAV

   Tags

   mScarlet-KASH-2A

   Expression

   Mutation

   Enzymatically inactive Cre

   Promoter

   Available since

   Aug. 7, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. PZac2.1 hSyn1-Lck-13xLinker-BioID2-BioID2-HA

   Plasmid

   #176854

   Purpose

   Expresses membrane bound biotin ligase, BioID2, in neurons

   Depositor

   Baljit Khakh

   Article

   Soto et al Nature. 2023 Apr;616(7958):764-773. doi:

   Insert

   Lck-13xLinker-BioID2-BioID2-HA
   

   Use

   AAV

   Tags

   HA

   Expression

   Bacterial

   Mutation

   Promoter

   hSyn1

   Available since

   April 11, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-hSyn1-SIO-eOPN3-mScarlet-WPRE

   Plasmid

   #125713

   Purpose

   Cre-dependent vector expressing an optimized mosquito OPN3 rhodopsin in-frame with mScarlet

   Depositor

   Ofer Yizhar

   Article

   Mahn et al Neuron. 2021 May 10. pii: S0896-6273(21)

   Has Service

   AAV1 and AAV5

   Insert

   eOPN3
   

   Use

   AAV and Cre/Lox

   Tags

   Rho1D4 and mScarlet

   Expression

   Mammalian

   Mutation

   deleted amino acids 331-429

   Promoter

   hSyn1

   Available since

   Sept. 20, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-hSyn1-DIO-Opto-cytTrkB(E281A)-HA

   Plasmid

   #180590

   Purpose

   Opto-cytTrkB

   Depositor

   Won Do Heo

   Article

   Hong J et al J Mol Biol. 2020 Feb 14;432(4):815-827.

   Insert

   TrkB
   

   Use

   AAV

   Tags

   Expression

   Mutation

   PHR(E281A)

   Promoter

   Available since

   Feb. 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV hSyn1 bPAC cMyc S27A 2A tDimer

   Plasmid

   #85398

   Purpose

   humanized photoactivated adenylyl cyclase lower dark activity, spectrum shifted 15 nm longer wavelenght with neuron-specific promoter, plus red fluorescent protein

   Depositor

   Thomas Oertner

   Inserts

   humanized photoactivated adenylyl cyclase
   red fluorescent protein
   

   Use

   AAV

   Tags

   cMyc Tag

   Expression

   Mammalian

   Mutation

   S27A

   Promoter

   human Synapsin1 promotor and ribosomal skip seque…

   Available since

   Jan. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV hSyn1 bPAC cMyc T2A tDimer

   Plasmid

   #85397

   Purpose

   humanized photoactivated adenylyl cyclase with cMyc Tag driven by neuron-specific promoter, plus red fluorescent protein

   Depositor

   Thomas Oertner

   Inserts

   humanized photoactivated adenylyl cyclase
   red fluorescent protein
   

   Use

   AAV

   Tags

   cMyc Tag

   Expression

   Mammalian

   Mutation

   Promoter

   human synapsin-1 and ribosomal skip sequence T2A

   Available since

   Jan. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. pOTTC813 - pAAV-SYN1-CRTsigpep-GCaMP3-KDEL

   Plasmid

   #63886

   Purpose

   An AAV packaging vector that expresses ER-retained GCaMP3 under control of the SYN1 promoter.

   Depositor

   Brandon Harvey

   Article

   Henderson et al PLoS One. 2015 Oct 9;10(10):e0139273. do

   Insert

   ER-localized GCaMP3(wt)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   human SYN1

   Available since

   Dec. 1, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-Syn1-DIO-Snca (human A53T)

   Plasmid

   #214201

   Purpose

   For Cre-dependent expression of alpha synuclein (human gene containing A53T mutation)

   Depositor

   Thomas Hnasko

   Article

   Steinkellner et al Brain. 2022 Apr 29;145(3):879-886. doi:

   Insert

   Snca (A53T) (SNCA Human)
   

   Use

   AAV and Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   A53T

   Promoter

   Available since

   March 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pOTTC1663 - pAAV SYN1 mGas6-Myc-DDK

   Plasmid

   #202540

   Purpose

   An adeno-associated viral vector expressing murine Gas6 fused Myc and DDK epitopes from a synapsin promoter

   Depositor

   Christopher Richie

   Article

   Owlett et al J Neuroinflammation. 2022 Feb 7;19(1):38

   Insert

   Gas6 (Gas6 Mouse)
   

   Use

   AAV

   Tags

   Myc-DDK

   Expression

   Mutation

   Promoter

   SYN1

   Available since

   June 20, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-hSyn1-FLEX-NEPLDCV-P2A-mRUBY3-WPRE

    Plasmid

    #207664

    Purpose

    Neuropeptide degradation

    Depositor

    Sung Han

    Article

    Kim et al bioRxiv 2023.01.19.524797

    Insert

    NEP (MME Human)
    

    Use

    AAV and Cre/Lox

    Tags

    mRUBY3

    Expression

    Mutation

    Addition of signaling peptide (POMC) on the N-ter…

    Promoter

    hSynapsin

    Available since

    Dec. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. AAV phSyn1(S)-FLEX-tdTomato-T2A-SypEGFP-WPRE

    Plasmid

    #51509

    Purpose

    Can be used to generate AAV virus that will express cytoplasmic tdTomato and presynaptic (synaptophysin-fused) EGFP in the presence of Cre in neurons from the synapsin promoter

    Depositor

    Hongkui Zeng

    Article

    Oh et al Nature. 2014 Apr 10;508(7495):207-14. do

    Has Service

    AAV1

    Insert

    tdTomato-T2A-SypEGFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    phSyn1

    Available since

    May 2, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-hSyn1-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA

    Plasmid

    #50942

    Purpose

    Bicistronic vector expressing mRuby2 and GCaMP6s from a single open reading frame.

    Depositor

    Tobias Bonhoeffer, Mark Huebener, Tobias Rose

    Article

    Rose et al Science. 2016 Jun 10;352(6291):1319-22.

    Has Service

    AAV1

    Insert

    mRuby2-P2A-GCaMP6s
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn1

    Available since

    March 25, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-hSyn1-mRuby2-GSG-P2A-GCaMP6f-WPRE-pA

    Plasmid

    #50943

    Purpose

    Bicistronic vector expressing mRuby2 and GCaMP6f from a single open reading frame.

    Depositor

    Tobias Bonhoeffer, Mark Huebener, Tobias Rose

    Article

    Rose et al Science. 2016 Jun 10;352(6291):1319-22.

    Insert

    mRuby2-P2A-GCaMP6f
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn1

    Available since

    March 25, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-hSyn1-EGFP-P2A-EGFPf-WPRE-HGHpA

    Plasmid

    #74513

    Purpose

    AAV vector that use human synapsin-1 promoter to drive the expression of EGFP and membrane-targeted EGFPf linked by self-cleaving P2A peptide.

    Depositor

    Guoping Feng

    Article

    Zhang et al J Neurosci. 2016 Feb 17;36(7):2247-60. d

    Insert

    EGFP-p2A-EGFP-f
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 20, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-hSyn1-mRuby2-GSG-P2A-GCaMP6m-WPRE-pA

    Plasmid

    #51473

    Purpose

    Bicistronic vector expressing mRuby2 and GCaMP6m from a single open reading frame.

    Depositor

    Tobias Bonhoeffer, Mark Huebener, Tobias Rose

    Article

    Rose et al Science. 2016 Jun 10;352(6291):1319-22.

    Insert

    mRuby2-P2A-GCaMP6m
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn1

    Available since

    April 16, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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16. pOTTC1784 - pAAV SYN1 hChR2(H134R)-V5-ER-LBD (ChRERa)

    Plasmid

    #201820

    Purpose

    An adeno-associated viral vector expressing channelrhodopsin-2 fused to a V5 epitope and the ligand-binding domain of estrogen receptor (ChRERa) from a synapsin promoter, for use in PET imaging

    Depositor

    Christopher Richie

    Article

    Bonaventura et al Sci Transl Med. 2023 Jul 26;15(706):eadd

    Insert

    hChR2(H134R)-V5-ER-LBD (ChRERa)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    SYN1

    Available since

    Oct. 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pOTTC1619 pAAV SYN1 Nuc-EYFP miR-30 SST

    Plasmid

    #135565

    Purpose

    An AAV vector expressing miR-30a shRNA vs rat SOM (aka SST) and a nuclear EYFP reporter

    Depositor

    Christopher Richie

    Article

    Venniro et al Proc Natl Acad Sci U S A. 2020 Apr 7;117

    Inserts

    miR-30 rat SST
    Nuc-EYFP
    

    Use

    AAV

    Tags

    3xNLS

    Expression

    Mammalian

    Mutation

    Promoter

    SYN1 and hSYN1

    Available since

    Sept. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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18. pOTTC1618 pAAV SYN1 Nuc-EYFP miR-30 FF3

    Plasmid

    #135564

    Purpose

    An AAV vector expressing miR-30a shRNA vs FF luciferase and a nuclear EYFP reporter

    Depositor

    Christopher Richie

    Article

    Venniro et al Proc Natl Acad Sci U S A. 2020 Apr 7;117

    Inserts

    miR-30 FF3
    Nuc-EYFP
    

    Use

    AAV

    Tags

    3xNLS

    Expression

    Mammalian

    Mutation

    Promoter

    SYN1 and hSYN1

    Available since

    Sept. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. pOTTC1664 - pAAV SYN1 mGas6(delta)-Myc-DDK

    Plasmid

    #202541

    Purpose

    An adeno-associated viral vector expressing murine Gas6 with deletion of (F50-E275) fused Myc and DDK epitopes from a synapsin promoter

    Depositor

    Christopher Richie

    Article

    Owlett et al J Neuroinflammation. 2022 Feb 7;19(1):38

    Insert

    Gas6 (Gas6 Mouse)
    

    Use

    AAV

    Tags

    Myc-DDK

    Expression

    Mutation

    Deletion of F50-E275

    Promoter

    SYN1

    Available since

    June 20, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pAAV-hSyn1-FLEX-NEPLDCV-P2A-mRUBY3-WPRE

    Plasmid

    #207664

    Purpose

    Neuropeptide degradation

    Depositor

    Sung Han

    Article

    Kim et al bioRxiv 2023.01.19.524797

    Insert

    NEP (MME Human)
    

    Use

    AAV and Cre/Lox

    Tags

    mRUBY3

    Expression

    Mutation

    Addition of signaling peptide (POMC) on the N-ter…

    Promoter

    hSynapsin

    Available since

    Dec. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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