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Plasmid#231990PurposeKnockout mouse Il1r1DepositorInsertsgRNA with Cas9 and hygromycin resistance (Il1r1 Mouse)
UseCRISPR and LentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 19, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLenti-multi-CRISPR-sgRipk3_#2-puro
Plasmid#231982PurposeKnockout mouse Ripk3DepositorInsertsgRNA with Cas9 with puromycin resistance (Ripk3 Mouse)
UseCRISPR and LentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLenti-multi-CRISPR-sgRipk3_#1-puro
Plasmid#231981PurposeKnockout mouse Ripk3DepositorInsertsgRNA with Cas9 with puromycin resistance (Ripk3 Mouse)
UseCRISPR and LentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLenti-multi-CRISPR-sgMlkl_#2-puro
Plasmid#231980PurposeKnockout mouse MlklDepositorInsertsgRNA with Cas9 with puromycin resistance (Mlkl Mouse)
UseCRISPR and LentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLenti-multi-CRISPR-sgMlkl_#1-puro
Plasmid#231979PurposeKnockout mouse MlklDepositorInsertsgRNA with Cas9 with puromycin resistance (Mlkl Mouse)
UseCRISPR and LentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLenti-multi-CRISPR-sgCasp8_#2-puro
Plasmid#231978PurposeKnockout mouse Casp8DepositorInsertsgRNA with Cas9 with puromycin resistance (Casp8 Mouse)
UseCRISPR and LentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLenti-multi-CRISPR-sgCasp8_#1-puro
Plasmid#231977PurposeKnockout mouse Casp8DepositorInsertsgRNA with Cas9 with puromycin resistance (Casp8 Mouse)
UseCRISPR and LentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLVX MLKL(1-180)-2A-mCherry-puro
Plasmid#231976PurposeTet inducible expression of DmrB-Mlkl with mCherry to induce MLKL 1-180 necroptosisDepositorInsertMLKL 1-180 construct with bi-cistronic mCherry (Mlkl Mouse)
UseLentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLVX MLKL(S345D)-2A-mCherry-puro
Plasmid#231975PurposeTet inducible expression of DmrB-Mlkl with mCherry to induce phosphomimetic MLKL S345D necroptosisDepositorInsertMLKL S345D construct with bi-cistronic mCherry (Mlkl Mouse)
UseLentiviralTagsExpressionMutationMLKL S345DPromoterAvailable sinceFeb. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLVX-DmrB-Casp8-2A-mCherry-puro
Plasmid#231971PurposeTet inducible expression of DmrB-Casp8 with mCherry to induce Casp8 apoptosisDepositorInsertCasp8 dimerizing construct with bi-cistronic mCherry (CASP8 Human)
UseLentiviralTagsExpressionMutationPromoterAvailable sinceFeb. 5, 2025AvailabilityAcademic Institutions and Nonprofits only -
phH1-GBX2-gRNA
Plasmid#192510PurposeContains gRNA for GBX2DepositorInsertGBX2 (GBX2 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 6, 2023AvailabilityAcademic Institutions and Nonprofits only -
phU6-CDX4-gRNA
Plasmid#192511PurposeContains gRNA for CDX4DepositorInsertCDX4 (CDX4 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 6, 2023AvailabilityAcademic Institutions and Nonprofits only -
pmU6-CDX1-gRNA
Plasmid#192512PurposeContains gRNA for CDX1DepositorInsertCDX1 (CDX1 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 6, 2023AvailabilityAcademic Institutions and Nonprofits only -
ph7SK-CDX2-gRNA
Plasmid#192513PurposeContains gRNA for CDX2DepositorInsertCDX2 (CDX2 Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceDec. 6, 2023AvailabilityAcademic Institutions and Nonprofits only -
pGL3-Basic-ZC3H12D_PromoterMUT
Plasmid#153067PurposeZC3H12D promoter region carrying mutations in BHLHE40 binding sites, cloned upstream of luciferase reporterDepositorInsertZC3H12D promoter region mutated in BHLHE40 binding sites (ZC3H12D Human)
UseLuciferaseTagsExpressionMammalianMutationMutagenesis to disrupt 3 BHLHE4040 binding sites.…PromoterNoneAvailable sinceSept. 15, 2020AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-hPC1_MTS_L4139P-eGFP-3HA
Plasmid#108404PurposeExpress putative mitochondrial targeting sequence of human PC1 from amino acid 4129 to 4157 with a likely pathogenic point mutation.DepositorInsertPKD1 (PKD1 Human)
UseTags3xHA and eGFPExpressionMammalianMutationPromoterCMVAvailable sinceAug. 14, 2018AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-hPC1_MTS_V4146I-eGFP
Plasmid#108405PurposeExpress putative mitochondrial targeting sequence of human PC1 from amino acid 4129 to 4157 with a likely non-pathogenic variant.DepositorInsertPKD1 (PKD1 Mouse)
UseTags3xHA and eGFPExpressionMammalianMutationPromoterCMVAvailable sinceApril 2, 2018AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-hPC1_MTS_L4137P-eGFP
Plasmid#108403PurposeExpress putative mitochondrial targeting sequence of human PC1 from amino acid 4129 to 4157 with a likely pathogenic point mutation.DepositorInsertPKD1 (PKD1 Mouse)
UseTags3xHA and eGFPExpressionMammalianMutationPromoterCMVAvailable sinceApril 2, 2018AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-hPC1_MTS-eGFP
Plasmid#108402PurposeExpress putative mitochondrial targeting sequence of human PC1 from amino acid 4129 to 4157DepositorInsertPKD1 (PKD1 Mouse)
UseTags3xHA and eGFPExpressionMammalianMutationPromoterCMVAvailable sinceApril 2, 2018AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_PSG2_WT
Plasmid#81917PurposeGateway Donor vector containing PSG2 ,part of the Target Accelerator Plasmid Collection.DepositorInsertPSG2 (PSG2 Human)
UseGateway entry vectorTagsExpressionMutationV20L; p.333_335del-NPT-ins-IQHPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SMR3A_WT
Plasmid#81887PurposeGateway Donor vector containing SMR3A , part of the Target Accelerator Plasmid Collection.DepositorInsertSMR3A (SMR3A Human)
UseGateway entry vectorTagsExpressionMutationC42R; P132LPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_C1orf150_WT
Plasmid#81842PurposeGateway Donor vector containing C1ORF150 , part of the Target Accelerator Plasmid Collection.DepositorInsertC1ORF150 (GCSAML Human)
UseGateway entry vectorTagsExpressionMutationWTPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_SPAG8_WT
Plasmid#81848PurposeGateway Donor vector containing SPAG8 , part of the Target Accelerator Plasmid Collection.DepositorInsertSPAG8 (SPAG8 Human)
UseGateway entry vectorTagsExpressionMutationE2D; E5G; P226LPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_CPXCR1_WT
Plasmid#81819PurposeGateway Donor vector containing CPXCR1 , part of the Target Accelerator Plasmid Collection.DepositorInsertCPXCR1 (CPXCR1 Human)
UseGateway entry vectorTagsExpressionMutationWTPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_OR2M2_WT
Plasmid#81758PurposeGateway Donor vector containing OR2M2 , part of the Target Accelerator Plasmid Collection.DepositorInsertOR2M2 (OR2M2 Human)
UseGateway entry vectorTagsExpressionMutationR220G, C235RPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_RAC1_WT
Plasmid#81749PurposeGateway Donor vector containing RAC1 , part of the Target Accelerator Plasmid Collection.DepositorInsertRAC1 (RAC1 Human)
UseGateway entry vectorTagsExpressionMutationT135IPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_MTM1_p.R253Q
Plasmid#81724PurposeGateway Donor vector containing MTM1, part of the Target Accelerator Plasmid Collection.DepositorInsertMTM1 (MTM1 Human)
UseGateway entry vectorTagsExpressionMutationR253Q; E410KPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_ZNF597_WT_V5
Plasmid#83003PurposeGateway Donor vector containing ZNF597, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.DepositorInsertZNF597 (ZNF597 Human)
UseGateway entry vectorTagsExpressionMutationPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_MTM1_p.P226S
Plasmid#81678PurposeGateway Donor vector containing MTM1, part of the Target Accelerator Plasmid Collection.DepositorInsertMTM1 (MTM1 Human)
UseGateway entry vectorTagsExpressionMutationP226S; E410KPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_OR2M2_p.N42Y
Plasmid#81638PurposeGateway Donor vector containing OR2M2, part of the Target Accelerator Plasmid Collection.DepositorInsertOR2M2 (OR2M2 Human)
UseGateway entry vectorTagsExpressionMutationN42Y; R220G; C235RPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only