We narrowed to 1,428 results for: aav vector plasmid

1. AAV:ITR-EF1aCore-SaCas9-single(U6-sgRNA(backbone))-ITR

   Plasmid

   #207880

   Purpose

   AAV vector encoding EF1a core promoter-driven SaCas9 and single sgRNA cloning site w/ the engineered Sa Guide scaffold variant (BbsI for sgRNA cloning).

   Depositor

   Yeh-Hsing Lao

   Article

   Lao et al Proc Natl Acad Sci U S A. 2023 Aug 22;12

   Type

   Empty backbone

   Use

   AAV and CRISPR

   Expression

   Mammalian

   Available Since

   Nov. 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-EFS-SaKKH-spA-miniU6-miniSdd6-MmHPD-T2

   Plasmid

   #204852

   Purpose

   AAV vector for cytosine base editing using miniSdd6 at HPD-T2 target site in mouse

   Depositor

   Caixia Gao

   Article

   Huang et al Cell. 2023 Jul 20;186(15):3182-3195.e14.

   Insert

   miniSdd6-nSaCas9KKH(D10A)-UGI
   

   Use

   AAV and CRISPR

   Mutation

   D10A, E782K, N968K, R1015H in SaCas9

   Promoter

   EFS, miniU6

   Available Since

   Aug. 17, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pOTTC1784 - pAAV SYN1 hChR2(H134R)-V5-ER-LBD (ChRERa)

   Plasmid

   #201820

   Purpose

   An adeno-associated viral vector expressing channelrhodopsin-2 fused to a V5 epitope and the ligand-binding domain of estrogen receptor (ChRERa) from a synapsin promoter, for use in PET imaging

   Depositor

   Christopher Richie

   Article

   Bonaventura et al Sci Transl Med. 2023 Jul 26;15(706):eadd

   Insert

   hChR2(H134R)-V5-ER-LBD (ChRERa)
   

   Use

   AAV

   Promoter

   SYN1

   Available Since

   Oct. 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pOTTC1845 - pAAV CaMKII hChR2(H134R)-V5-ER-LBD (ChRERa)

   Plasmid

   #201822

   Purpose

   An adeno-associated viral vector expressing channelrhodopsin-2 fused to a V5 epitope and the ligand-binding domain of estrogen receptor (ChRERa) from a CaMKii promoter, for use in PET imaging

   Depositor

   Christopher Richie

   Article

   Bonaventura et al Sci Transl Med. 2023 Jul 26;15(706):eadd

   Insert

   hChR2(H134R)-V5-ER-LBD (ChRERa)
   

   Use

   AAV

   Promoter

   CaMKii

   Available Since

   Oct. 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pX602-AAV-TBG::NLS-SaCas9-NLS-HA-OLLAS-bGHpA;U6::BsaI-sgRNA

   Plasmid

   #61593

   Purpose

   A single vector AAV-Cas9 system containing Cas9 from Staphylococcus aureus (SaCas9) and its sgRNA.

   Depositor

   Feng Zhang

   Article

   Ran et al Nature. 2015 Apr 1. doi: 10.1038/nature1

   Inserts

   hSaCas9
   Chimeric guide for SaCas9
   

   Use

   AAV and CRISPR

   Tags

   HA, NLS, and OLLAS tag

   Expression

   Mammalian

   Mutation

   K175R and K736R (deUb mutations)

   Available Since

   Feb. 16, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-S5E7-dTom-nls-dTom

   Plasmid

   #135642

   Purpose

   AAV vector to drive the expression of dTomato in PV cortical interneuronsunder the control of the E7 regulatory element

   Depositor

   Jordane Dimidschstein

   Article

   Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

   Insert

   dTom-nlsdTom
   

   Use

   AAV

   Mutation

   None

   Available Since

   Aug. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-S5E9-dTom-nls-dTom

   Plasmid

   #135644

   Purpose

   AAV vector to drive the expression of dTomato in PV cortical interneuronsunder the control of the E9 regulatory element

   Depositor

   Jordane Dimidschstein

   Article

   Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

   Insert

   dTom-nlsdTom
   

   Use

   AAV

   Mutation

   None

   Available Since

   Aug. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP

   Plasmid

   #112677

   Purpose

   An AAV vector that expresses a Cre-dependent nuclear-localized Red to Green Fluorescent protein

   Depositor

   Brandon Harvey

   Article

   Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

   Has Service

   AAV Retrograde, AAV1, AAV2, AAV5, AAV8, and AAV9

   Insert

   Nuclear-localized floxed-mCherry EGFP
   

   Use

   AAV

   Tags

   Nuclear localization signal

   Promoter

   EF1a

   Available Since

   March 7, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pOTTC1179 - pAAV (flox-stop) TH gRNA A EF1a eGFP

   Plasmid

   #113158

   Purpose

   An AAV vector that expresses a Cre-dependent guide RNA targeting rat TH and expresses EGFP reporter

   Depositor

   Brandon Harvey

   Article

   Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

   Insert

   gRNA for rat TH
   

   Use

   AAV, CRISPR, and Cre/Lox

   Expression

   Mammalian

   Promoter

   mU6

   Available Since

   March 7, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. pOTTC1822 - pAAV SYN1 DIO hChR2(H134R)-V5-ER-LBD (ChRERa)

    Plasmid

    #201821

    Purpose

    An adeno-associated viral vector expressing Cre-dependent channelrhodopsin-2 fused to a V5 epitope and the ligand-binding domain of estrogen receptor (ChRERa) from a synapsin promoter, for use in PET

    Depositor

    Christopher Richie

    Article

    Bonaventura et al Sci Transl Med. 2023 Jul 26;15(706):eadd

    Insert

    hChR2(H134R)-V5-ER-LBD (ChRERa)
    

    Use

    AAV

    Promoter

    SYN1

    Available Since

    Oct. 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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