We narrowed to 2,556 results for: neurod

1. pCMV CHMP2B-L4D,F5D-V82E-3XHA

   Plasmid

   #242393

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with a V82E mutation and a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D V82E

   Promoter

   CMV

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCMV CHMP2B-L4D,F5D-M92E-3XHA

   Plasmid

   #242417

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with a M92E mutation and a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D M92E

   Promoter

   CMV

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCMV CHMP2B-L4D F5D-d106-113-3xHA (Δα3)

   Plasmid

   #232007

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with the third alpha helix deleted with a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D Δ106-113

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCMV CHMP2B-L4D F5D-d118-138-3xHA (Δα4)

   Plasmid

   #232008

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with the fourth alpha helix deleted with a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D Δ118-138

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCMV CHMP2B-L4D F5D-d55-138-3xHA (Δα2-4)

   Plasmid

   #232009

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with the second through fourth helices deleted with a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D Δ55-138

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCMV CHMP2B-L4D F5D-d159-174-3xHA (Δα5)

   Plasmid

   #232010

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with the fifth alpha helix deleted with a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D Δ159-174

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCMV CHMP2B-L4D F5D-d201-213-HA (ΔVPS4 binding)

   Plasmid

   #232011

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with the VPS4-binding region deleted with a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   L4D F5D Δ201-213

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCMV CHMP2B-L4D F5D-d10-52-3xHA (Δα1)

   Plasmid

   #232004

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with the first alpha helix deleted with a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D Δ10-52

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCMV CHMP2B-L4D F5D-d55-96-3xHA (Δα2)

   Plasmid

   #232005

   Purpose

   Expression of a CHMP2B membrane binding mutant (L4D F5D) with the second alpha helix deleted with a 3xHA tag.

   Depositor

   Franz-Ulrich Hartl

   Article

   Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

   Insert

   CHMP2B (CHMP2B Human)
   

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   L4D F5D Δ55-96

   Available Since

   Aug. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCMV CHMP2B-L4D F5D-d97-106-3xHA (Δα2/3 loop)

    Plasmid

    #232006

    Purpose

    Expression of a CHMP2B membrane binding mutant (L4D F5D) with the loop connecting the second and third alpha helices deleted with a 3xHA tag.

    Depositor

    Franz-Ulrich Hartl

    Article

    Sitron et al Mol Cell. 2025 Sep 18;85(18):3505-3523.e

    Insert

    CHMP2B (CHMP2B Human)
    

    Tags

    3xHA

    Expression

    Mammalian

    Mutation

    L4D F5D Δ97-106

    Available Since

    Aug. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLentiX1-[TRE3G-FXN-P2A-mRuby2-bGH]-EFS-rtTA-P2A-mGL-WPRE

    Plasmid

    #235303

    Purpose

    Lentiviral expression of ComMAND base gene regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Lentiviral and Synthetic Biology

    Expression

    Mammalian

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLentiX1-[TRE3G-FXN-P2A-mRuby2(miRE.FF4)-TS.FF6x1-bGH]-EFS-rtTA-P2A-mGL-WPRE

    Plasmid

    #235304

    Purpose

    Lentiviral expression of ComMAND open-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Lentiviral and Synthetic Biology

    Expression

    Mammalian

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLentiX1-[TRE3G-FXN-P2A-mRuby2(miRE.FF4)-TS.FF4x1-bGH]-EFS-rtTA-P2A-mGL-WPRE

    Plasmid

    #235305

    Purpose

    Lentiviral expression of ComMAND closed-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Lentiviral and Synthetic Biology

    Expression

    Mammalian

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pX458_mCherry-FUS-gRNA

    Plasmid

    #237685

    Purpose

    Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to FUS locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    FUS gRNA (FUS Human)
    

    Use

    CRISPR

    Tags

    mCherry

    Available Since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pHLsec hSOD1

    Plasmid

    #232481

    Purpose

    vector for transient transfection expressing human SOD1gene including flag-tag (DYKDDDDK) on the 3' end

    Depositor

    Lukas Trantirek

    Article

    Rynes et al Commun Biol. 2025 Feb 7;8(1):194. doi: 1

    Insert

    Homo sapiens superoxide dismutase 1 (SOD1 Human)
    

    Tags

    DYKDDDDK (FLAG-tag)

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLenti_SIV-(SalI)-syn-IRES-mEmerald-CaV2.1 WPRE

    Plasmid

    #236239

    Purpose

    Lentiviral expression of voltage-gated calcium channel, CaV2.1, N-terminally tagged with mEmerald

    Depositor

    Jennifer Lippincott-Schwartz

    Article

    Benedetti et al Cell. 2025 Jan 23;188(2):484-500.e22. do

    Insert

    CaV2.1 (CACNA1A Rabbit)
    

    Use

    Lentiviral

    Tags

    mEmerald

    Promoter

    human Synapsin 1

    Available Since

    May 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pMRX-IP-EGFP-PA-BAX(lyso, G108V)

    Plasmid

    #233345

    Purpose

    Stable expression of EGFP-LOV2(G528A, N538E)-BAX-TMEM106B in mammalian cells. The G108V mutation suppresses pore-forming activity of BAX.

    Depositor

    Noboru Mizushima

    Article

    Nagashima et al J Biol Chem. 2025 Mar 18;301(4):108421.

    Inserts

    LOV2 domain of phototropin1
    BAX (BAX Human)
    TMEM106B (TMEM106B Human)
    

    Use

    Retroviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    BAX(3-171), N-terminus and C-terminus are deleted…

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pMRX-IP-EGFP-PA-BAX(lyso)

    Plasmid

    #228939

    Purpose

    Stable expression of EGFP-LOV2(G528A, N538E)-BAX-TMEM106B in mammalian cells. Photoactivatable BAX localizes on lysosomal membrane and induces lysosomal rupture upon blue light stimulation.

    Depositor

    Noboru Mizushima

    Article

    Nagashima et al J Biol Chem. 2025 Mar 18;301(4):108421.

    Inserts

    LOV2 domain of phototropin1
    BAX (BAX Human)
    TMEM106B (TMEM106B Human)
    

    Use

    Retroviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    N-terminus and C-terminus are deleted. BAX(3-171)…

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. 7AA-aSyn-pRK172

    Plasmid

    #236197

    Purpose

    This plasmid expresses human α-synuclein with a 7-amino acid insertion (MAAAEKT) in the pRK172 backbone for bacterial expression in E. coli. The insertion corresponds to the JOS mutation.

    Depositor

    Yang Yang, Sjors Scheres

    Article

    Yang et al Acta Neuropathol. 2023 May;145(5):561-57

    Insert

    SNCA (SNCA Human)
    

    Expression

    Bacterial

    Mutation

    insertion os MAAAEKT at residue 22

    Available Since

    April 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. TH1150-pOCC177-FUS(Nhe)-PLD_YtoF_RGG_RtoK

    Plasmid

    #221889

    Purpose

    Shuttle vector for baculovirus production, using FlashBac bacmid

    Depositor

    Anthony Hyman

    Article

    Wang et al Cell. 2018 Jul 26;174(3):688-699.e16. do

    Insert

    FUS (FUS Human)
    

    Tags

    6xHis-MBP-PreScission and TEV-SNAP-tag

    Expression

    Insect

    Mutation

    In PLD all Tyr (Y) changed to Phe (F), in RGG (aa…

    Promoter

    PH promoter

    Available Since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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