Sequence Type

BLAST Database

BLAST Algorithm

Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

We narrowed to 24,971 results for: Spr

Showing: 701 - 750 of 24971 results

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pLENTICRISPR V2 hygro sgmPOLE_2

Plasmid

#241443

Purpose

Delete mouse Pole

Depositor

Richard Possemato

Insert

sgmPOLE_2 (POLE Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR V2 hygro sgmPOLE_1

Plasmid

#241442

Purpose

Delete mouse Pole

Depositor

Richard Possemato

Insert

sgmPOLE_1 (POLE Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 2, 2026

Availability

Academic Institutions and Nonprofits only

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EML8359_pA3A-CBECas9-ALSpro197

Plasmid

#234353

Purpose

Base editor targets to ALS Pro197 locus

Depositor

Erh-Min Lai

Article

Liu et al New Phytol. 2025 Nov 30. doi: 10.1111/np

Insert

ALS

Use

CRISPR

Expression

Plant

Available Since

Nov. 25, 2025

Availability

Academic Institutions and Nonprofits only

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pSC-pGAL10-CRISPRa

Plasmid

#240210

Purpose

Yeast vector for integration of pGAL10-dCas9 and pGAL10-MCP-VPR at LEU2 locus

Depositor

Wilfred Chen

Article

Stohr et al Nucleic Acids Res. 2025 Nov 13;53(21):gk

Inserts

MCP-VPR
dCas9

Expression

Yeast

Promoter

pGAL10

Available Since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR V2 Hygro sgRELB_1

Plasmid

#241452

Purpose

Delete RELB

Depositor

Richard Possemato

Insert

sgRELB_1 (RELB Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Nov. 6, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLENTICRISPR V2-mCherry sgmRELA_1

Plasmid

#241447

Purpose

Delete mouse Rela

Depositor

Richard Possemato

Insert

sgmRELA_1 (RELA Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Nov. 6, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLENTICRISPR V2 Hygro sgIKBKG_1

Plasmid

#241449

Purpose

Delete IKBKG

Depositor

Richard Possemato

Insert

sgIKBKG_1 (IKBKG Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Nov. 6, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLENTICRISPR V2 Hygro sgRELA_4

Plasmid

#241446

Purpose

Delete RELA

Depositor

Richard Possemato

Insert

sgRELA_4 (RELA Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Nov. 6, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLENTICRISPR V2 Hygro sgIKBKG_2

Plasmid

#241450

Purpose

Delete IKBKG

Depositor

Richard Possemato

Insert

sgIKBKG_2 (IKBKG Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Nov. 6, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 sgYME1L1 sg1

Plasmid

#244867

Purpose

Knockout of human YME1L1

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

YME1L1 sgRNA (YME1L1 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Nov. 5, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 sgOMA1 sg2

Plasmid

#244866

Purpose

Knockout of human OMA1

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

OMA1 sgRNA (OMA1 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 sgYME1L1 sg2

Plasmid

#244868

Purpose

Knockout of human YME1L1

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

YME1L1 sgRNA (YME1L1 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 CLUH sg1

Plasmid

#244857

Purpose

Knockout of human CLUH

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

CLUH sgRNA (CLUH Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR PARL sg1

Plasmid

#244853

Purpose

Knockout of human PARL

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

PARL sgRNA (PARL Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR PARL sg2

Plasmid

#244854

Purpose

Knockout of human PARL

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

PARL sgRNA (PARL Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 CLUH sg2

Plasmid

#244858

Purpose

Knockout of human CLUH

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

CLUH sgRNA (CLUH Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR IMMP2L sg2

Plasmid

#244852

Purpose

Knockout of human IMMP2L

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

IMMP2L sgRNA (IMMP2L Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 sgOMA1 sg1

Plasmid

#244865

Purpose

Knockout of human OMA1

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

OMA1 sgRNA (OMA1 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR IMMP1L sg2

Plasmid

#244850

Purpose

Knockout of human IMMP1L

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

IMMP1L sgRNA (IMMP1L Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR IMMP1L sg1

Plasmid

#244849

Purpose

Knockout of human IMMP1L

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

IMMP1L sgRNA (IMMP1L Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR IMMP2L sg1

Plasmid

#244851

Purpose

Knockout of human IMMP2L

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

IMMP2L sgRNA (IMMP2L Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR ATP23 sg1

Plasmid

#244847

Purpose

Knockout of human ATP23

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

ATP23 sgRNA (XRCC6BP1 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR ATP23 sg2

Plasmid

#244848

Purpose

Knockout of human ATP23

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

ATP23 sgRNA (XRCC6BP1 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_2xsgRNAs_RPP21 (pAVA3259)

Plasmid

#239327

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting RPP21

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting RPP21 (RPP21 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 11, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pNS1D-sgRNA9-SpR

Plasmid

#191092

Purpose

aTc inducible gRNA expression plasmid with BbsI sites for Golden Gate insertion of crRNA oligos and homology arms for genome integration at NS1D in Synechococcus sp. PCC 7002

Depositor

Anne Ruffing

Article

Dallo et al ACS Synth Biol. 2023 Apr 21;12(4):1175-1

Type

Empty backbone

Use

CRISPR

Expression

Bacterial

Promoter

tet

Available Since

Aug. 11, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_2xsgRNAs_BRF2 (pAVA3258)

Plasmid

#239326

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting BRF2

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting BRF2 (BRF2 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_2xsgRNAs_RPPH1 (pAVA3586)

Plasmid

#239328

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting RPPH1

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting RPPH1 (RPPH1 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_D11 (pAVA3773)

Plasmid

#239310

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and a non-targeting sgRNA as control(-)

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven non-targeting sgRNA Control(-)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_POP1 (pAVA3497)

Plasmid

#239311

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting POP1

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting POP1 (POP1 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP38 (pAVA3523)

Plasmid

#239313

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP38

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP38 (RPP38 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP29 (pAVA3545)

Plasmid

#239314

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP29

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP29 (POP4 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_POP5 (pAVA3498)

Plasmid

#239315

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting POP5

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting POP5 (POP5 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP20 (pAVA3546)

Plasmid

#239316

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP20

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP20 (POP7 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP14 (pAVA3507)

Plasmid

#239317

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP14

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP14 (RPP14 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP30 (pAVA3573)

Plasmid

#239318

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP30

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP30 (RPP30 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP40 (pAVA3540)

Plasmid

#239319

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP40

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP40 (RPP40 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP25 (pAVA3522)

Plasmid

#239320

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP25

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP25 (RPP25 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_RPP25L (pAVA3548)

Plasmid

#239321

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting RPP25L

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting RPP25L (RPP25L Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_2xsgRNAs_RBM7 (pAVA3250)

Plasmid

#239322

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting RBM7

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting RBM7 (RBM7 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_2xsgRNAs_SKIV2L2 (pAVA3251)

Plasmid

#239323

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting SKIV2L2

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting SKIV2L2 (MTREX Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_2xsgRNAs_ZCRB1 (pAVA3300)

Plasmid

#239325

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNA stargeting ZCRB1

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting ZCRB1 (ZCRB1 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_EXOSC10 (pAVA3318)

Plasmid

#239295

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC10

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting EXOSC10 (EXOSC10 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_DDX59 (pAVA3791)

Plasmid

#239297

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting DDX59

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting DDX59 (DDX59 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_DDX59 (pAVA3796)

Plasmid

#239298

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting DDX59

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting DDX59 (DDX59 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_DDX59 (pAVA3317)

Plasmid

#239299

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting DDX59

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting DDX59 (DDX59 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
LentiCRISPR-B_sgRNA_DDX59 (pAVA3794)

Plasmid

#239300

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting DDX59

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting DDX59 (DDX59 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPRv2 Neo-MORC3_gRNA_1

Plasmid

#235529

Purpose

gRNA against human MORC3

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

MORC3 (MORC3 Human)

Use

Lentiviral

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPRv2 Neo-MORC3_gRNA_3

Plasmid

#235530

Purpose

gRNA against human MORC3

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

MORC3 (MORC3 Human)

Use

Lentiviral

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPRv2-ICAM-5-Puro

Plasmid

#239949

Purpose

CRISPR KO of human ICAM-5

Depositor

Jan Carette

Article

Varanese et al Nature. 2025 Mar 25. doi: 10.1038/s41586

Insert

ICAM-5

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPRv2-MFSD6-Puro

Plasmid

#239950

Purpose

CRISPR KO of human MFSD6

Depositor

Jan Carette

Article

Varanese et al Nature. 2025 Mar 25. doi: 10.1038/s41586

Insert

MFSD6

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge

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