Addgene

We narrowed to 340 results for: Lrrk2;

Showing: 321 - 340 of 340 results

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Lenti-guide-puro mCct8 - 1

Plasmid

#198503

Purpose

lentiviral stable expression of mCct8 gRNA 1

Depositor

Suzanne Pfeffer

Article

Dhekne et al Elife. 2023 Oct 24;12:e87098. doi: 10.75

Insert

mCct8 (Cct8 Mouse)

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

April 21, 2023

Availability

Academic Institutions and Nonprofits only

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pJWK_VD_04

Plasmid

#158105

Purpose

CaV1.3 5'UTR luciferase reporter

Depositor

Ted Dawson

Article

Kim et al Cell Stem Cell. 2020 Oct 1;27(4):633-645

Insert

5'UTR of CACNA1D (uc003dgu.5)

Use

Luciferase

Tags

Expression

Mammalian

Mutation

Promoter

PGK

Available since

Aug. 18, 2020

Availability

Academic Institutions and Nonprofits only

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pJWK_VD_03

Plasmid

#158104

Purpose

CaV1.2 5'UTR luciferase reporter

Depositor

Ted Dawson

Article

Kim et al Cell Stem Cell. 2020 Oct 1;27(4):633-645

Insert

5'UTR of CACNA1C (uc009zdu.1)

Use

Luciferase

Tags

Expression

Mammalian

Mutation

Promoter

PGK

Available since

Aug. 18, 2020

Availability

Academic Institutions and Nonprofits only

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pEMB52/Armadillo_34_373

Plasmid

#40543

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2

Use

Baculovirus

Tags

6xHis

Expression

Mutation

WT

Promoter

polH

Available since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

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pEMB52/Horse_34_374

Plasmid

#40544

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2

Use

Baculovirus

Tags

6xHis

Expression

Mutation

WT

Promoter

polH

Available since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

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pEMB52/Turkey_34_374

Plasmid

#40545

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2

Use

Baculovirus

Tags

6xHis

Expression

Mutation

WT

Promoter

polH

Available since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

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pSIN-PAmCherry-KFERQ-NE

Plasmid

#102365

Purpose

Lentiviral overexpression of PA-mCherry-KFERQ fusion

Depositor

Shu Leong Ho

Article

Ho et al Autophagy. 2019 Apr 14:1-24. doi: 10.108

Inserts

PA-mCherry
KFERQ peptide

Use

Lentiviral

Tags

NE

Expression

Mammalian

Mutation

Promoter

EF-1a

Available since

Dec. 18, 2017

Availability

Academic Institutions and Nonprofits only

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pcDNA3-Flag-NSF

Plasmid

#74924

Purpose

Mammalian expression of human NSF full-length (744 aa)

Depositor

Elisa Greggio

Article

Belluzzi et al Mol Neurodegener. 2016 Jan 13;11(1):1. d

Insert

NSF (NSF Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

Promoter

CMV

Available since

April 20, 2016

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1-hSNCA-NE

Plasmid

#102361

Purpose

Overexpression of synuclein alpha in mammalian cells

Depositor

Shu Leong Ho

Article

Ho et al Autophagy. 2019 Apr 14:1-24. doi: 10.108

Insert

synuclein alpha (SNCA Human)

Use

Tags

NE

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Dec. 18, 2017

Availability

Academic Institutions and Nonprofits only

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pJWK_VD_01

Plasmid

#158102

Purpose

5'UTR stem-loop luciferase reporter: 0kcal/mol

Depositor

Ted Dawson

Article

Kim et al Cell Stem Cell. 2020 Oct 1;27(4):633-645

Insert

5'UTR synthetic stem-loop 0kcal/mol

Use

Luciferase

Tags

Expression

Mammalian

Mutation

Promoter

PGK

Available since

Aug. 18, 2020

Availability

Academic Institutions and Nonprofits only

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pJWK_VD_02

Plasmid

#158103

Purpose

5'UTR stem-loop luciferase reporter: -30kcal/mol

Depositor

Ted Dawson

Article

Kim et al Cell Stem Cell. 2020 Oct 1;27(4):633-645

Insert

5'UTR synthetic stem-loop -30kcal/mol

Use

Luciferase

Tags

Expression

Mammalian

Mutation

Promoter

PGK

Available since

Aug. 18, 2020

Availability

Academic Institutions and Nonprofits only

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pcDNA3-Flag-NSF/S647A

Plasmid

#74938

Purpose

Mammalian expression of human NSF mutant S647A (mutation in the D2 domain of the protein)

Depositor

Elisa Greggio

Article

Belluzzi et al Mol Neurodegener. 2016 Jan 13;11(1):1. d

Insert

NSF (NSF Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

S647A (mutation in the D2 domain of the protein)

Promoter

CMV

Available since

April 20, 2016

Availability

Academic Institutions and Nonprofits only
pcDNA3-Flag-NSF/T646A

Plasmid

#74937

Purpose

Mammalian expression of human NSF mutant T646A (mutation in the D2 domain of the protein)

Depositor

Elisa Greggio

Article

Belluzzi et al Mol Neurodegener. 2016 Jan 13;11(1):1. d

Insert

NSF (NSF Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

T646A (mutation in the D2 domain of the protein)

Promoter

CMV

Available since

April 26, 2016

Availability

Academic Institutions and Nonprofits only
pcDNA3-Flag-NSF/T645A

Plasmid

#74936

Purpose

Mammalian expression of human NSF mutant T645A (mutation in the D2 domain of the protein)

Depositor

Elisa Greggio

Article

Belluzzi et al Mol Neurodegener. 2016 Jan 13;11(1):1. d

Insert

NSF (NSF Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

T645A (mutation in the D2 domain of the protein)

Promoter

CMV

Available since

April 20, 2016

Availability

Academic Institutions and Nonprofits only
pMCB306-GFP-mito

Plasmid

#229232

Purpose

Expresses GFP localized to mitochondria

Depositor

Suzanne Pfeffer

Article

Bagnoli et al Proc Natl Acad Sci U S A. 2025 Feb 4;122

Insert

EGFP-MAOA (MAOA Human)

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Feb. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pSIN-PAmCherry-mSNCA-NE

Plasmid

#102364

Purpose

Lentiviral overexpression of PA-mCherry synuclein alpha fusion

Depositor

Shu Leong Ho

Article

Ho et al Autophagy. 2019 Apr 14:1-24. doi: 10.108

Inserts

PA-mCherry
synuclein alpha (Snca Mouse)

Use

Lentiviral

Tags

NE

Expression

Mammalian

Mutation

Promoter

EF-1a

Available since

April 19, 2018

Availability

Academic Institutions and Nonprofits only

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pSIN-hSNCA-NE

Plasmid

#102366

Purpose

Lentiviral overexpression of synuclein alpha

Depositor

Shu Leong Ho

Article

Ho et al Autophagy. 2019 Apr 14:1-24. doi: 10.108

Insert

synuclein alpha (SNCA Human)

Use

Lentiviral

Tags

NE

Expression

Mammalian

Mutation

A silent mutation (333bp downstream of ATG) was i…

Promoter

EF-1a

Available since

April 19, 2018

Availability

Academic Institutions and Nonprofits only

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His-SUMO-Rab10 Q68L

Plasmid

#236720

Purpose

Expresses Rab10 Q68L with His tag and SUMO cleavage sequence

Depositor

Suzanne Pfeffer

Article

Claire Y. et al bioRxiv, 2025

Insert

Rab10 Q68L (RAB10 Human)

Use

Tags

6xHis-SUMO

Expression

Bacterial

Mutation

Q68L

Promoter

T7

Available since

May 7, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV5D HA-PPM1H_M flap

Plasmid

#236718

Purpose

Expresses PPM1H with PPM1M flap domain sequence

Depositor

Suzanne Pfeffer

Article

Claire Y. et al bioRxiv, 2025

Insert

PPM1H_M flap (PPM1H, PPM1M Human)

Use

Tags

HA

Expression

Mammalian

Mutation

PPM1H flap domain replaced with PPM1M flap domain

Promoter

CMV

Available since

May 7, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV5D HA-PPM1M_H flap

Plasmid

#236719

Purpose

Expresses PPM1M with PPM1H flap domain sequence

Depositor

Suzanne Pfeffer

Article

Claire Y. et al bioRxiv, 2025

Insert

PPM1M_H flap (PPM1M, PPM1H Human)

Use

Tags

HA

Expression

Mammalian

Mutation

PPM1M flap domain replaced with PPM1H flap domain

Promoter

CMV

Available since

May 7, 2025

Availability

Academic Institutions and Nonprofits only

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