We narrowed to 28,253 results for: tat

Showing: 3521 - 3540 of 28253 results

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pcDNA3_ATP10B-E993A

Plasmid

#203698

Purpose

expresses ATP10B with the pathogenic mutation E993A

Depositor

Peter Vangheluwe

Article

Martin et al Acta Neuropathol. 2020 Jun;139(6):1001-1

Insert

ATP10B (ATP10B Human)

Expression

Mammalian

Mutation

E993A

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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pcDNA3_ATP10B-E210A

Plasmid

#203697

Purpose

expresses ATP10B with the catalytic mutation E210A

Depositor

Peter Vangheluwe

Article

Martin et al Acta Neuropathol. 2020 Jun;139(6):1001-1

Insert

ATP10B (ATP10B Human)

Expression

Mammalian

Mutation

E210A

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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pcDNA3_ATP10B-D433N

Plasmid

#203696

Purpose

expresses ATP10B with the catalytic mutation D433N

Depositor

Peter Vangheluwe

Article

Martin et al Acta Neuropathol. 2020 Jun;139(6):1001-1

Insert

ATP10B (ATP10B Human)

Expression

Mammalian

Mutation

D433N

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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pcDNA3_ATP10B-V748L

Plasmid

#203702

Purpose

expresses ATP10B with the pathogenic mutation V748L

Depositor

Peter Vangheluwe

Article

Martin et al Acta Neuropathol. 2020 Jun;139(6):1001-1

Insert

ATP10B (ATP10B Human)

Expression

Mammalian

Mutation

V748L

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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pcDNA3_ATP10B-I1038T

Plasmid

#203700

Purpose

expresses ATP10B with the pathogenic mutation I1038T

Depositor

Peter Vangheluwe

Article

Martin et al Acta Neuropathol. 2020 Jun;139(6):1001-1

Insert

ATP10B (ATP10B Human)

Expression

Mammalian

Mutation

I1038T

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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pcDNA3_ATP10B-R153X

Plasmid

#203701

Purpose

expresses ATP10B with the pathogenic mutation R153X

Depositor

Peter Vangheluwe

Article

Martin et al Acta Neuropathol. 2020 Jun;139(6):1001-1

Insert

ATP10B (ATP10B Human)

Expression

Mammalian

Mutation

R153X

Available Since

Nov. 6, 2023

Availability

Academic Institutions and Nonprofits only

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pT2/shCol1a1/Scarlet_Seq1.3

Plasmid

#206137

Purpose

Knockdown of Collagen Type 1 alpha 1. Construct has inverted repeats to be used in Sleeping Beauty transposon system.

Depositor

Maria Castro

Article

Comba et al Nat Commun. 2022 Jun 24;13(1):3606. doi:

Insert

COL1A1 (Col1a1 Mouse)

Expression

Mammalian

Available Since

Sept. 11, 2023

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(+)-R/G-ICUE

Plasmid

#181849

Purpose

ICUE cAMP sensor using sfGFP and mRuby2 as the FRET donor and acceptor.

Depositor

Jin Zhang

Article

Zhang et al Cell. 2020 Sep 17;182(6):1531-1544.e15.

Insert

R/G-ICUE (RAPGEF3 Human)

Tags

mRuby2 and sfGFP

Expression

Mammalian

Mutation

Glutamine 122 in Epac1 domain mutated to glutamat…

Promoter

CMV

Available Since

July 6, 2022

Availability

Academic Institutions and Nonprofits only

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pLKO.1-shDnd1-No5

Plasmid

#70066

Purpose

TRC lentiviral vector for shRNA against mouse Dnd1 #5

Depositor

Thomas Tuschl

Article

Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

Insert

Dnd1 (Dnd1 Mouse)

Use

Lentiviral

Expression

Mammalian

Promoter

EF1alpha

Available Since

Nov. 22, 2017

Availability

Academic Institutions and Nonprofits only

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pLuc-Optop38i-dsm

Plasmid

#89748

Purpose

Expression of light-regulated p38 inhibitor, firefly luciferase-fused, dark-state mutant photosensor (AsLov2Ja.C450A), inhibitor MK3BD3-13F

Depositor

Michael Courtney

Article

Melero-Fernandez de Mera et al Nat Commun. 2017 May 12;8:15017. doi: 10

Insert

Optop38i dark-state mutant

Use

Luciferase

Tags

Firefly luciferase

Expression

Mammalian

Mutation

C450A mutation of AsLov2Jalpha

Promoter

CMV

Available Since

Aug. 29, 2017

Availability

Academic Institutions and Nonprofits only

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pMDC43-FIT2-FLL[157-159]AAA

Plasmid

#96994

Purpose

Express GFP-tagged mutated mouse FIT2 gene in plants.

Depositor

Kent Chapman

Article

Cai et al Plant Biotechnol J. 2016 Dec 17. doi: 10

Insert

MmFIT2 (Fitm2 Mouse)

Tags

GFP

Expression

Plant

Mutation

Amino acid residues 157-159 were mutated (FLL[157…

Promoter

35S

Available Since

Aug. 17, 2017

Availability

Academic Institutions and Nonprofits only

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pSico shMAP3K2 mouse

Plasmid

#85657

Purpose

expression of shRNA targeting mouse MAP3K2

Depositor

Julien Sage

Article

Mazur et al Nature. 2014 Jun 12;510(7504):283-7. doi

Insert

shRNA targeting 3'UTR of Map3k2 (Map3k2 Mouse)

Use

Lentiviral and RNAi

Expression

Mammalian

Promoter

U6

Available Since

Feb. 2, 2017

Availability

Academic Institutions and Nonprofits only

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FLT1 gRNA (BRDN0001146782)

Plasmid

#75558

Purpose

3rd generation lentiviral gRNA plasmid targeting human FLT1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FLT1 (FLT1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pIS1 mHK1

Plasmid

#60795

Purpose

Luciferase reporter to measure miR-155 mediated differential repression. Contains HK1 3' UTR and mutated miR-155 sites

Depositor

David Bartel

Article

Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

Insert

HK1 3'UTR and mutated miR-155 binding site (HK1 Human)

Use

Luciferase

Expression

Mammalian

Mutation

mutated miR-155 binding site

Promoter

thymidine kinase (HSV-TK promoter)

Available Since

Oct. 20, 2014

Availability

Academic Institutions and Nonprofits only

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pMiR-CIP2A-stop-mut

Plasmid

#53713

Purpose

Luciferase reporter assay for CIP2A with mutated firefly stop codon

Depositor

Edward Chan

Article

Jung et al Mol Biol Cell. 2013 Jun;24(11):1638-48,

Insert

CIP2A (CIP2A Human)

Use

Luciferase

Mutation

Mutation on the stop codon of firefly luciferase …

Available Since

July 2, 2014

Availability

Academic Institutions and Nonprofits only
pRRLNeo-pEF1a-p53ashL344A-mKate2-splitmVenusN

Plasmid

#69584

Purpose

Expresses mutated p53-L344A tagged with mKate2 and split N-term mVenus

Depositor

Galit Lahav

Article

Gaglia et al Mol Syst Biol. 2014 Oct 24;10:753. doi:

Insert

p53-L344A (TP53 Human)

Use

Lentiviral

Tags

mKate2 and split mVenus - N term

Expression

Mammalian

Mutation

p53 L344A mutation that prevents tetramerization …

Promoter

EF1alpha

Availability

Academic Institutions and Nonprofits only

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MSCVneo-HA-ER-Hoxb8

Plasmid

#222291

Purpose

The most commonly used plasmid for the generation of ER-Hoxb8 conditionally immortalized myeloid cell lines.

Depositor

Mark Kamps, David Sykes

Article

Wang et al Nat Methods. 2006 Apr;3(4):287-93.

Insert

ER-Hoxb8 (ESR1, Hoxb8 Mouse, Human)

Use

Retroviral

Tags

HA

Expression

Mammalian

Mutation

The estrogen receptor hormone binding domain cont…

Available Since

Nov. 19, 2024

Availability

Academic Institutions and Nonprofits only

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pMXS-IRES-BLAST flag-CAD T456A S1406A S1859A

Plasmid

#169826

Purpose

Expresses C-terminal flag-tagged CAD with mutation of reported S6K, PKA, and Erk1/2 phosphorylation site

Depositor

Richard Possemato

Article

Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

Insert

CAD (CAD Human)

Use

Retroviral

Tags

Flag tag

Expression

Mammalian

Mutation

T456A S1406A S1859A; TCCC -> AGTC silent mutat…

Available Since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

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pETDuet_huCAD_ICADL (TevS)

Plasmid

#100098

Purpose

dual expression of human CAD and ICAD. The two caspase cleavage sites in ICAD were mutated to TEVP cleavable sequences

Depositor

Jim Wells

Article

Morgan et al Proc Natl Acad Sci U S A. 2015 Jul 7;112

Insert

DNA fragmentation factor subunit alpha (CAD, DFFA Human)

Expression

Bacterial

Mutation

two caspase cleavage sites (DETD-117 and DAVD-224…

Promoter

T7

Available Since

Jan. 11, 2018

Availability

Academic Institutions and Nonprofits only

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pCMV-eGFP-uTEV3

Plasmid

#234320

Purpose

Mammalian expression of uTEV3 tagged with an eGFP marker

Depositor

Mateo Sánchez

Article

Silva-Rojas et al Nat Biomed Eng. 2025 Jun 5. doi: 10.1038

Insert

eGFP-uTEV3

Use

AAV

Tags

eGFP

Expression

Mammalian

Mutation

Mutations respective to the wild type TEV: S219V …

Promoter

CMV

Available Since

June 5, 2025

Availability

Academic Institutions and Nonprofits only

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