We narrowed to 10,450 results for: ESP

1. SHLD1 N-terminal sgRNA

   Plasmid

   #207101

   Purpose

   pX330 based plasmid for expression of Cas9 and the ATGGCAGGACTATGGCAGCC sgRNA to target the SHLD1 locus.

   Depositor

   Jens Schmidt

   Article

   Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

   Insert

   ATGGCAGGACTATGGCAGCC
   

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   May 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. ATM C-terminal sgRNA

   Plasmid

   #207097

   Purpose

   pX330 based plasmid for expression of Cas9 and the TTTCTAAAGGCTGAATGAAA sgRNA to target the ATM locus.

   Depositor

   Jens Schmidt

   Article

   Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

   Insert

   TTTCTAAAGGCTGAATGAAA
   

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   May 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. msFam160b1 (msFHIP2A) g1 lentiCRISPRv2-mCherry

   Plasmid

   #218654

   Purpose

   Knockout vector for mouse Fam160b1 (Fhip2A)

   Depositor

   Wade Harper

   Article

   Hollingsworth et al bioRxiv 2024.04.19.590338

   Insert

   Fam160b1 (Fhip2a Mouse)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   May 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pDONR221 msNLRP3(ΔPYD, I125M-END) (STOP)

   Plasmid

   #218640

   Purpose

   Gateway shuttling vector for cloning N-terminal NLRP3(ΔPYD, I125M-END) tags (contains a stop codon)

   Depositor

   Wade Harper

   Article

   Hollingsworth et al bioRxiv 2024.04.19.590338

   Insert

   NLRP3 (Nlrp3 Mouse)
   

   Use

   Gateway entry

   Mutation

   delPYD (I125M-END)

   Available Since

   May 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pDONR221 hNLRP3 R262W (disease-associated mutation)

   Plasmid

   #218647

   Purpose

   Gateway shuttling vector for cloning NLRP3-R262W (no stop codon)

   Depositor

   Wade Harper

   Article

   Hollingsworth et al bioRxiv 2024.04.19.590338

   Insert

   NLRP3 (NLRP3 Human)
   

   Use

   Gateway entry

   Mutation

   R262W

   Available Since

   May 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pDONR221 msNLRP3(ΔPYD, I125M-END)

   Plasmid

   #218641

   Purpose

   Gateway shuttling vector for cloning N- and C-terminal NLRP3(ΔPYD, I125M-END) tags (contains no stop codon)

   Depositor

   Wade Harper

   Article

   Hollingsworth et al bioRxiv 2024.04.19.590338

   Insert

   NLRP3 (Nlrp3 Mouse)
   

   Use

   Gateway entry

   Mutation

   delPYD (I125M-END)

   Available Since

   May 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. msFam160b1 (msFHIP2A) g2 lentiCRISPRv2 mCherry

   Plasmid

   #218655

   Purpose

   Knockout vector for mouse Fam160b1 (Fhip2A)

   Depositor

   Wade Harper

   Article

   Hollingsworth et al bioRxiv 2024.04.19.590338

   Insert

   Fam160b1 (Fhip2a Mouse)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   May 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLV UBC msNLRP3(LRRm5)-APEX2-3xFLAG-IRES-eGFP (H781E_Q782R_F785A)

   Plasmid

   #218636

   Purpose

   Proximity biotinylation of msNLRP3(LRRm5, H781E_Q782R_F785A)

   Depositor

   Wade Harper

   Article

   Hollingsworth et al bioRxiv 2024.04.19.590338

   Insert

   NLRP3 (Nlrp3 Mouse)
   

   Use

   Lentiviral

   Tags

   APEX2-3xFLAG

   Expression

   Mammalian

   Mutation

   H781E, Q782R, F785A

   Promoter

   UBC

   Available Since

   May 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. SHLD3 KO sgRNA #1

   Plasmid

   #207105

   Purpose

   pX330 based plasmid for expression of Cas9 and the CGCTATCAAGATTTATACCT sgRNA to target the SHLD3 locus..

   Depositor

   Jens Schmidt

   Article

   Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

   Insert

   CGCTATCAAGATTTATACCT
   

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   April 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pKJ318

    Plasmid

    #217495

    Purpose

    Mammlian expression of MmFnuc guide RNA

    Depositor

    Omar Abudayyeh, Jonathan Gootenberg

    Article

    Jiang et al Sci Adv. 2023 Sep 29;9(39):eadk0171. doi

    Insert

    MmFnuc guide RNA scaffold
    

    Expression

    Mammalian

    Available Since

    April 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pKJ234

    Plasmid

    #217492

    Purpose

    Mammlian expression of DpFnuc for genome editing

    Depositor

    Omar Abudayyeh, Jonathan Gootenberg

    Article

    Jiang et al Sci Adv. 2023 Sep 29;9(39):eadk0171. doi

    Insert

    DpFnuc
    

    Expression

    Mammalian

    Available Since

    April 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. SHLD2 N-terminal sgRNA

    Plasmid

    #207098

    Purpose

    pX330 based plasmid for expression of Cas9 and the TTTTTATCAGAAATCATGAG sgRNA to target the SHLD2 locus.

    Depositor

    Jens Schmidt

    Article

    Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

    Insert

    TTTTTATCAGAAATCATGAG
    

    Expression

    Mammalian

    Promoter

    CMV and U6

    Available Since

    April 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pTwist Amp msTMEM115-TEV-3C-P2A-mScarlet-I HDR Template

    Plasmid

    #215000

    Purpose

    Endogenously tag mouse TMEM115 with a C-terminal 3xHA tag in addition to cytosolic mScarlet-I for cell sorting.

    Depositor

    Wade Harper

    Article

    Hollingsworth et al bioRxiv 2024.04.19.590338

    Insert

    msTMEM115-TEV-3C-P2A-mScarlet-I HDR Template (Tmem115 Mouse)
    

    Use

    Hdr template

    Tags

    3xHA

    Promoter

    None

    Available Since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pKJ221

    Plasmid

    #212319

    Purpose

    Express MmFnuc guide with pureexpress

    Depositor

    Omar Abudayyeh, Jonathan Gootenberg

    Article

    Jiang et al Sci Adv. 2023 Sep 29;9(39):eadk0171. doi

    Insert

    Mercenaria guide
    

    Expression

    Bacterial

    Available Since

    April 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. HaloTag KO sgRNA

    Plasmid

    #207102

    Purpose

    pX330 based plasmid for expression of Cas9 and the GTCGATGTTGGTCCGCGCGA sgRNA to target the HaloTag coding sequence.

    Depositor

    Jens Schmidt

    Article

    Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

    Insert

    GTCGATGTTGGTCCGCGCGA
    

    Expression

    Mammalian

    Promoter

    CMV and U6

    Available Since

    March 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. MDC1 N-terminal sgRNA

    Plasmid

    #207090

    Purpose

    pX330 based plasmid for expression of Cas9 and the GTATCCTTCCCAGATCATGG sgRNA to target the MDC1 locus.

    Depositor

    Jens Schmidt

    Article

    Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

    Insert

    GTATCCTTCCCAGATCATGG
    

    Expression

    Mammalian

    Promoter

    CMV and U6

    Available Since

    March 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. SHLD3 KO sgRNA #2

    Plasmid

    #207106

    Purpose

    pX330 based plasmid for expression of Cas9 and the CTGAAGGAACAGACTAATTC sgRNA to target the SHLD3 locus..

    Depositor

    Jens Schmidt

    Article

    Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

    Insert

    CTGAAGGAACAGACTAATTC
    

    Expression

    Mammalian

    Promoter

    CMV and U6

    Available Since

    March 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. 53BP1 KO sgRNA

    Plasmid

    #207104

    Purpose

    pX330 based plasmid for expression of Cas9 and the AGATTCTCAGCCTGAAAGCC sgRNA to target the 53BP1 coding sequence.

    Depositor

    Jens Schmidt

    Article

    Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

    Insert

    AGATTCTCAGCCTGAAAGCC
    

    Expression

    Mammalian

    Promoter

    CMV and U6

    Available Since

    March 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pKJ238

    Plasmid

    #212321

    Purpose

    Express KnFnuc guide with pureexpress

    Depositor

    Omar Abudayyeh, Jonathan Gootenberg

    Article

    Jiang et al Sci Adv. 2023 Sep 29;9(39):eadk0171. doi

    Insert

    KnFunc guide
    

    Expression

    Bacterial

    Available Since

    Feb. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pOTTC1992 - pAAV EF1a CoV2 Orf3a-2xStrep

    Plasmid

    #213542

    Purpose

    AAV viral vector packaging plasmid that expresses CoV2

    Depositor

    Brandon Harvey, Christopher Richie

    Insert

    CoV2 Orf3a-2xStrep (ORF3a Human, Severe acute respiratory syndrome coronavirus 2)
    

    Use

    AAV

    Promoter

    EF1a

    Available Since

    Feb. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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