We narrowed to 9,193 results for: Pol;

1. pEMS2026

   Plasmid

   #49133

   Purpose

   AAV plasmid with TNNT1-B (Ple301) promoter driving expression of iCre.

   Depositor

   Elizabeth Simpson

   Article

   Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

   Insert

   ssAAV-Ple301-iCre
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   TNNT1-B

   Available Since

   May 10, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. pTSara-N748D

   Plasmid

   #60726

   Purpose

   Expresses both fragments of T7 RNAP split at position 179. Both fragments are driven by PBAD. The C-terminal fragment has the point mutation N748D. Contains a constitutive araC ORF

   Depositor

   Matthew Bennett

   Article

   Shis et al Proc Natl Acad Sci U S A. 2013 Mar 26;11

   Inserts

   Residues 1-179 of split T7 RNAP
   Residues 180-880 of split T7 RNAP
   

   Use

   Synthetic Biology

   Expression

   Bacterial

   Mutation

   Residues 1-180 of split T7 RNAP and Residues 180-…

   Available Since

   Oct. 2, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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3. huCofilin S3E SSR

   Plasmid

   #245940

   Purpose

   Expresses human cofilin with mutation S3E that behaves like inactive phosphocofilin but can be dominant negative against phosphatase

   Depositor

   James Bamburg

   Article

   Agnew et al J Biol Chem. 1995 Jul 21;270(29):17582-7

   Insert

   cofilin 1 (cfl1) (CFL1 Human)
   

   Expression

   Mammalian

   Mutation

   S3E; silent mutations (NTs 67 to 75) in which TCT…

   Promoter

   CMV

   Available Since

   Oct. 21, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pDonr201_PARP1_del119/120

   Plasmid

   #240318

   Purpose

   Entry vector for Gateway with PARP1 (AA119/120 deletion)

   Depositor

   Junjie Chen

   Article

   Nie et al Elife. 2024 Apr 5;12:RP89303. doi: 10.75

   Insert

   PARP1 (PARP1 Human)
   

   Expression

   Bacterial

   Mutation

   AA119/120 was deleted

   Available Since

   Oct. 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLV-Hygro-EF1A-TRIP12(749-836)-EGFP

   Plasmid

   #196229

   Purpose

   EGFP fused to the C-terminus of a WWE domain within TRIP12 & a hygromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Al-Rahahleh et al DNA Repair (Amst). 2025 Jun;150:103845.

   Insert

   C-terminal EGFP tagged TRIP12(749- 836)
   

   Use

   Lentiviral

   Tags

   EGFP and Myc tag

   Expression

   Mammalian

   Promoter

   EF1A

   Available Since

   Aug. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLV-Hygro-EF1A-DTX2(8-174)-EGFP

   Plasmid

   #196232

   Purpose

   EGFP fused to the C-terminus of tandem WWE domains within Deltex2 & a hygromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Al-Rahahleh et al DNA Repair (Amst). 2025 Jun;150:103845.

   Insert

   DTX2(8-174)-EGFP
   

   Use

   Lentiviral

   Tags

   EGFP and Myc tag

   Expression

   Mammalian

   Promoter

   EF1A

   Available Since

   Aug. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLV-Hygro-EF1A-Af1521(K35E/Y145R)-EGFP

   Plasmid

   #196235

   Purpose

   EGFP fused to the C-terminus of Af1521(K35E/Y145R) macrodomain & a hygromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Al-Rahahleh et al DNA Repair (Amst). 2025 Jun;150:103845.

   Insert

   C-terminal EGFP tagged Af1521(K35E/Y145R)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   K35E and Y145R

   Promoter

   EF1A

   Available Since

   Aug. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLV-Hygro-EF1A-RNF146(100-182)-myc

   Plasmid

   #196236

   Purpose

   RNF146(100-182) WWE domain with a myc tag fused to the C terminus & a hygromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Al-Rahahleh et al DNA Repair (Amst). 2025 Jun;150:103845.

   Insert

   RNF146(100-182) encoding a C-terminal myc tag
   

   Use

   Lentiviral

   Tags

   myc tag

   Expression

   Mammalian

   Promoter

   EF1A

   Available Since

   Aug. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. PX459_NRF2-exon5-1

   Plasmid

   #177781

   Purpose

   sgRNA for CRISPR/Cas9-mediated deletion of human NRF2

   Depositor

   Michael Ristow

   Article

   Thomas et al Nat Commun. 2023 Dec 8;14(1):8142. doi:

   Insert

   NRF2 (NFE2L2 Human)
   

   Use

   CRISPR

   Available Since

   Aug. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. PX459_NRF2-exon5-2

    Plasmid

    #177782

    Purpose

    sgRNA for CRISPR/Cas9-mediated deletion of human NRF2

    Depositor

    Michael Ristow

    Article

    Thomas et al Nat Commun. 2023 Dec 8;14(1):8142. doi:

    Insert

    NRF2 (NFE2L2 Human)
    

    Use

    CRISPR

    Available Since

    Aug. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. yTREX-ApR

    Plasmid

    #177307

    Purpose

    genomic integration of genes (inserted in I-SceI-site) via transposon Tn5

    Depositor

    Karl-Erich Jaeger

    Article

    Weihmann et al FEMS Microbes. 2022 Dec 19;4:xtac030. do

    Type

    Empty backbone

    Use

    Synthetic Biology; Yeast expression, tn5 genomic …

    Expression

    Bacterial

    Available Since

    Aug. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pRK5R DD-FAM98B[1-330]

    Plasmid

    #211358

    Purpose

    Transient expression of DD-V5-FAM98B[1-330]

    Depositor

    Raghu Chivukula

    Article

    Yang et al Science. 2025 Jul 17;389(6757):eado2403.

    Insert

    DD-FAM98B[1-330] (FAM98B Human)
    

    Tags

    DD-V5

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLV-mCherry-Parkin

    Plasmid

    #237397

    Purpose

    Lentivirus plasmid for the stable expression of mCherry-Parkin in mammalian cells

    Depositor

    James Hurley

    Article

    Rose et al Proc Natl Acad Sci U S A. 2025 Aug 5;122

    Insert

    PRKN (PRKN Human)
    

    Use

    Lentiviral

    Tags

    mCherry

    Expression

    Mammalian

    Promoter

    EF1A

    Available Since

    Aug. 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pN3-sTRAIL

    Plasmid

    #154246

    Purpose

    Plasmid compatible with non-viral delivery for secretion of trimeric human TRAIL

    Depositor

    Jordan Green

    Article

    Vaughan et al Mol Ther Oncolytics. 2021 Apr 16;21:377-

    Insert

    Secretable Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand
    

    Expression

    Mammalian

    Promoter

    CMV Promoter

    Available Since

    July 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. M7138

    Plasmid

    #219774

    Purpose

    MoClo-compatible Level M vector encoding hygromycin resistance cassette and a luciferase gene under control of ORCA3 promoter and terminator

    Depositor

    Karen Sarkisyan

    Article

    Balakireva et al bioRxiv 2025.02.17.636591; doi: https://

    Insert

    pNOS-HygR-ocsT | pORCA3-nnLuz-ORCA3_T
    

    Use

    Synthetic Biology

    Expression

    Plant

    Promoter

    pNOS-HygR-ocsT | pORCA3-nnLuz-ORCA3_T

    Available Since

    July 21, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. M7691

    Plasmid

    #219775

    Purpose

    MoClo-compatible Level M vector encoding hygromycin resistance cassette and a luciferase gene under control of WRKY70 promoter and terminator

    Depositor

    Karen Sarkisyan

    Article

    Balakireva et al bioRxiv 2025.02.17.636591; doi: https://

    Insert

    pNOS-HygR-ocsT | pWRKY70-nnLuz-WRKY70_T
    

    Use

    Synthetic Biology

    Expression

    Plant

    Promoter

    pNOS-HygR-ocsT | pWRKY70-nnLuz-WRKY70_T

    Available Since

    July 21, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pNK3558

    Plasmid

    #219776

    Purpose

    MoClo-compatible Level M vector encoding hygromycin resistance cassette and a luciferase gene under control of p35S promoter and act2 terminator

    Depositor

    Karen Sarkisyan

    Article

    Balakireva et al bioRxiv 2025.02.17.636591; doi: https://

    Insert

    pNOS-HygR-ocsT | p35S-nnLuz-act2
    

    Use

    Synthetic Biology

    Expression

    Plant

    Promoter

    pNOS-HygR-ocsT | p35S-nnLuz-act2

    Available Since

    July 21, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. FUS LC TtoS

    Plasmid

    #226608

    Purpose

    All threonines to serine

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 4QQ->GG (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    4 QQ pairs replaced with GG pairs

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. FUS LC QtoA

    Plasmid

    #226609

    Purpose

    All glutamines to alanine

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    6*His-TEV-FUS LC QtoA (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    All glutamine to alanine

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. FUS LC 12S->G

    Plasmid

    #226597

    Purpose

    12 serines to glycines

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 12S->A (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    12 serines to alanine

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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21. FUS LC 12S->A

    Plasmid

    #226598

    Purpose

    12 serines to alanines

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 12S->A (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    12 serines to alanine

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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22. FUS LC 12S->N

    Plasmid

    #226599

    Purpose

    12 serines to asparagines

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 12S->N (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    12 serines to asparagine

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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23. FUS LC 4S->A#1

    Plasmid

    #226603

    Purpose

    4 serines to alanine at residue positions 30, 44, 48, 53

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC S->A#1 (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    4 serines to alanine in sequence position subset …

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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24. FUS LC 4S->A#2

    Plasmid

    #226604

    Purpose

    4 serines to alanine at residue positions 70, 84, 89, 95

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 4S->A#2 (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    4 serines to alanine in sequence position subset …

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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25. FUS LC 4S->A#3

    Plasmid

    #226605

    Purpose

    4 serines to alanine at residue positions 108, 117, 119, 127

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 4S->A#3 (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    4 serines to alanine in sequence position subset …

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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26. FUS LC StoG

    Plasmid

    #226607

    Purpose

    All serines to glycines

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC TtoS (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    All threonine to serine

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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27. pTMiniTrex-mCherry-Shark3

    Plasmid

    #233145

    Purpose

    Serves as a template plasmid for amplifying Shark3 (Theo-OFF) hammerhead aptazyme-3xTy-tagging cassette

    Depositor

    Ronald Etheridge

    Article

    Wiedeman et al Proc Natl Acad Sci U S A. 2025 Feb 25;12

    Inserts

    mCherry
    Shark3
    

    Use

    Prokaryotic expression

    Tags

    3x Ty tag

    Mutation

    Codon optimized for Trypanosoma cruzi and changed…

    Available Since

    March 20, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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28. pGM63

    Plasmid

    #220169

    Purpose

    CRISRPi guide RNA against TOMM70A

    Depositor

    Jonathan Weissman

    Article

    Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

    Insert

    TOMM70A (sgRNA) (TOMM70 Human)
    

    Use

    Lentiviral

    Available Since

    Feb. 25, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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29. p35S-FHA-AtAGO4_gDNA

    Plasmid

    #216838

    Purpose

    N-term Flag-HA tagged Arabidopsis thaliana (Col-0) AGO4 gDNA under regulation of CaMV 35S promoter

    Depositor

    Arturo Marí-Ordóñez

    Article

    Dombey et al bioRxiv 2024.04.03.587901; doi: https://

    Insert

    ARGONAUTE4 (AGO4 Mustard Weed)
    

    Tags

    Flag-HA

    Expression

    Plant

    Promoter

    CaMV 35S

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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30. Str-KDEL_SBP-EGFP-CCR5

    Plasmid

    #222309

    Purpose

    Synchronize the trafficking of CCR5 from the ER.

    Depositor

    Franck Perez

    Article

    Boncompain et al Sci Adv. 2019 Oct 16;5(10):eaax0821. doi

    Insert

    Streptavidin-KDEL and CCR5 fused to SBP-EGFP (CCR5 Human)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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