Sequence Type

BLAST Database

BLAST Algorithm

Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

We narrowed to 42,135 results for: LAS

Showing: 7741 - 7760 of 42135 results

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pAAV_BiLAMP5e3_ChR2_mCherry

Plasmid

#213915

Purpose

AAV construct expressing mCherry-tagged channelrhodopsin-2 driven by Lamp5 interneuron-targeting enhancer. Alias: pAAV_WDL0003_ChR2_mCherry

Depositor

Gordon Fishell

Article

Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

Has Service

AAV PHP.eB and AAV1

Insert

Channelrhodopsin 2-mCherry

Use

AAV

Available Since

July 23, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV_BiSSTe10_Gq_dTomato

Plasmid

#213817

Purpose

AAV construct expressing HA-hM3Dq-dTomato driven by SST interneuron-targeting enhancer. Alias: pAAV_S9E10_Gq_dTomato

Depositor

Gordon Fishell

Article

Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

Insert

HA-GqDREADD-dTomato

Use

AAV

Available Since

July 23, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV_BiLAMP5e3_GCaMP6f

Plasmid

#213917

Purpose

AAV construct expressing GCaMP6f driven by Lamp5 interneuron-targeting enhancer. Alias: pAAV_WDL0003_GCaMP6f

Depositor

Gordon Fishell

Article

Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

Has Service

AAV1

Insert

GCaMP6f

Use

AAV

Available Since

July 23, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-dLight3.6

Plasmid

#257858

Purpose

Expression of the green genetically encoded dopamine sensor dLight3.6 in mammalian cells under CAG promoter.

Depositor

Lin Tian

Insert

dLight3.6

Use

AAV

Expression

Mammalian

Promoter

CAG

Available Since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-dLight3.8

Plasmid

#257855

Purpose

Expression of the green genetically encoded dopamine sensor dLight3.8 under synapsin promoter.

Depositor

Lin Tian

Insert

dLight3.8

Use

AAV

Expression

Mammalian

Promoter

Synapsin

Available Since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-dLight3.6

Plasmid

#257854

Purpose

Expression of the green genetically encoded dopamine sensor dLight3.6 under synapsin promoter.

Depositor

Lin Tian

Insert

dLight3.6

Use

AAV

Expression

Mammalian

Promoter

Synapsin

Available Since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-DIO-dLight3.6

Plasmid

#257856

Purpose

Cre-dependent expression of the green genetically encoded dopamine sensor dLight3.6 under synapsin promoter.

Depositor

Lin Tian

Insert

dLight3.6

Use

AAV and Cre/Lox

Expression

Mammalian

Promoter

Synapsin

Available Since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pCMV-SpCas9-VRQR(+L1111R)-P2A-EGFP (LRF167)

Plasmid

#242673

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(L1111R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(L1111R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + L1111R mutations in SpCas9(L1111R/D1135V/G…

Promoter

CMV and T7

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV-SpCas9-VRQR(+A1322R)-P2A-EGFP (LRF59)

Plasmid

#242679

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(A1322R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(A1322R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + A1322R mutations in SpCas9(D1135V/G1218R/A…

Promoter

CMV and T7

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV-SpCas9-VRQR(+R221K)-P2A-EGFP (LRF95)

Plasmid

#242666

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(R221K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(R221K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + R221K mutations in SpCas9(R221K/D1135V/G12…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV-eVRQR-P2A-EGFP (KAC1028)

Plasmid

#242663

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-eVRQR(S55R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-eVRQR(S55R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

eVRQR mutations in SpCas9(S55R/D1135V/G1218R/R133…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV-SpCas9-VRQR(+N394K)-P2A-EGFP (KAC956)

Plasmid

#242670

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(N394K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(N394K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + N394K mutations in SpCas9(N394K/D1135V/G12…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

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pCMV-SpCas9-VRQR(+D269A)-P2A-EGFP (LRF64)

Plasmid

#242668

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(D269A)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(D269A)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + D269A mutations in SpCas9(D269A/D1135V/G12…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-SpCas9-VRQR(+G366R)-P2A-EGFP (KAC1026)

Plasmid

#242669

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(G366R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(G366R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + G366R mutations in SpCas9(G366R/D1135V/G12…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-SpCas9-VRQR(+N1286Q)-P2A-EGFP (LRF247)

Plasmid

#242677

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(N1286Q)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(N1286Q)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + N1286Q mutations in SpCas9(D1135V/G1218R/N…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-SpCas9-VRQR(+G1104K)-P2A-EGFP (LRF54)

Plasmid

#242671

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(G1140K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(G1140K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + G1104K mutations in SpCas9(G1104K/D1135V/G…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-SpCas9-VRQR(+A61R)-P2A-EGFP (KAC1030)

Plasmid

#242665

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(A61R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(A61R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + A61R mutations in SpCas9(A61R/D1135V/G1218…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-SpCas9-VRQR(+L244Q)-P2A-EGFP (LRF96)

Plasmid

#242667

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(L244Q)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(L244Q)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + L244Q mutations in SpCas9(L244Q/D1135V/G12…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-SpCas9-VRQR(+N1317R)-P2A-EGFP (LRF53)

Plasmid

#242678

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(N1317R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(N1317R)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + N1317R mutations in SpCas9(D1135V/G1218R/N…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-SpCas9-VRQR(+A1285K)-P2A-EGFP (KAC1134)

Plasmid

#242676

Purpose

CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(A1285K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

Insert

pCMV-SpCas9-VRQR(A1285K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

Use

CRISPR

Tags

BPNLS

Expression

Mammalian

Mutation

VRQR + A1285K mutations in SpCas9(D1135V/G1218R/A…

Promoter

CMV and T7

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge

Showing: 7741 - 7760 of 42135 results

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