We narrowed to 10,134 results for: ada

1. AAV-CMV-scFVtet1_bGHpA

   Plasmid

   #177351

   Purpose

   AAV expression of scFV-fused catalytic domain of TET1 for targeted DNA methylation editing

   Depositor

   Naoki Yamamoto

   Article

   Yamamoto et al Research Square [Preprint] 2021. doi: 10

   Insert

   Tet Methylcytosine Dioxygenase 1 (TET1 Human)
   

   Use

   AAV

   Tags

   myc and scFV

   Expression

   Mammalian

   Mutation

   N terminal domain of human Tet1

   Promoter

   CMV promoter

   Available Since

   Sept. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. 8798 GFP-KrasG12C_2B_hygro

   Plasmid

   #64376

   Purpose

   This a retroviral expression plasmid expressing GFP tagged G12C mutant Kras 2B oncogene along with hygro resistance gene

   Depositor

   Georgios Stathopoulos

   Article

   Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

   Insert

   mouse Kras2B (Kras Mouse)
   

   Use

   Retroviral

   Tags

   GFP

   Mutation

   changed glycine 12 to cysteine

   Available Since

   July 3, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCAG-VHC

   Plasmid

   #112618

   Purpose

   expression plasmid with CAG promoter driving multicistronic cassette H2BVenus_p2A_HygroR_p2A_CreERt2

   Depositor

   Stefan Heller

   Article

   Hartman et al Dev Biol. 2018 Sep 1. pii: S0012-1606(18

   Inserts

   H2B-Venus (H2BC3 Aequorea victoria, Human)
   Hygrophosphotransferase
   Cre-ERT2 fusion protein
   

   Tags

   Venus

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   Sept. 13, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pD649-HAsp-NOTCH3(Trunc1)-Fc(DAPA)-AviTag-6xHis

   Plasmid

   #157045

   Purpose

   Mammalian expression of cell-surface protein partial extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

   Depositor

   Chris Garcia

   Article

   Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

   Insert

   NOTCH3 (NOTCH3 Human)
   

   Tags

   Fc(DAPA)-AviTag-6xHis

   Expression

   Mammalian

   Mutation

   Fc region of human IgG contains D265A and P329A m…

   Promoter

   CMV/SP6

   Available Since

   March 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCW57.1 KBTBD4 R313PRR

   Plasmid

   #184626

   Purpose

   Doxycycline inducible lentiviral vector for N-terminal Flag tagged KBTBD4 R313PRR expression in mammalian cells

   Depositor

   Vincenzo D'Angiolella

   Article

   Chen et al Cell Death Differ. 2022 Apr 4. pii: 10.1

   Insert

   N-terminal Flag tagged KBTBD4 R313PRR (KBTBD4 Human)
   

   Use

   Lentiviral; Doxycycline inducible

   Expression

   Mammalian

   Mutation

   R313PRR

   Promoter

   TRE promoter, Tet ON

   Available Since

   June 3, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pcDNA5-FRT/TO-V5-SHLD3

   Plasmid

   #114124

   Purpose

   Expresses N-terminally tagged V5-SHLD3 in mammalian cells

   Depositor

   Daniel Durocher

   Article

   Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

   Insert

   SHLD3 (SHLD3 Human)
   

   Use

   Genomic integration, tetracycline inducible

   Tags

   V5

   Expression

   Mammalian

   Promoter

   CMV/TetO2

   Available Since

   Aug. 23, 2018

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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7. pLV-hCCND1-T286A-HA

   Plasmid

   #174155

   Purpose

   Lentiviral vector expressing HA-tagged human cyclin D1 with T286A mutation

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   CCND1 (CCND1 Human)
   

   Use

   Lentiviral

   Tags

   hemagglutinin (HA)

   Expression

   Mammalian

   Mutation

   A>G at base 856 (Thr>Ala at amino acid 286)

   Promoter

   EF1A

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. 8047_GFP-Kras2B_ires_puro

   Plasmid

   #64371

   Purpose

   This a retroviral expression plasmid expressing GFP tagged wild type Kras 2B oncogene along with puro resistance gene

   Depositor

   Georgios Stathopoulos

   Article

   Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

   Insert

   mouse Kras2B (Kras Mouse)
   

   Use

   Retroviral

   Tags

   GFP

   Mutation

   none

   Available Since

   July 3, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. DHC1-AID-Clover donor (Neo)

   Plasmid

   #158621

   Purpose

   Donor plasmid for tagging DHC1 with AID-Clover

   Depositor

   Masato Kanemaki

   Article

   Yesbolatova et al Nat Commun. 2020 Nov 11;11(1):5701. doi:

   Insert

   DHC1 (DYNC1H1 Human)
   

   Use

   CRISPR; Tagging donor

   Available Since

   Nov. 12, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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10. pMX-53BP1(1-1710) 3LA

    Plasmid

    #185698

    Purpose

    Mammalian Expression, Retroviral vector that encodes a 3LA mutant of 53BP1 that disrupts three RIF1-binding motifs and abolishes the 53BP1-dependent recruitment of RIF1 to DNA double-strand breaks.

    Depositor

    Daniel Durocher

    Article

    Setiaputra et al Mol Cell. 2022 Apr 7;82(7):1359-1371.e9.

    Insert

    53BP1(1-1710) 3LA (TP53BP1 Human)
    

    Use

    Retroviral

    Tags

    Flag tag, HA tag, and tetracysteine tag

    Expression

    Mammalian

    Mutation

    L175A, L517A, and L693A

    Promoter

    SV40

    Available Since

    July 7, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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11. pMX-53BP1(1-1710) 3LA7A

    Plasmid

    #185707

    Purpose

    Mammalian Expression, Retroviral vector that encodes 7A and 3LA mutant of 53BP1. Prevents shieldin and RIF1 recruitment to sites of double-strand breaks and disrupts 53BP1 activity.

    Depositor

    Daniel Durocher

    Article

    Setiaputra et al Mol Cell. 2022 Apr 7;82(7):1359-1371.e9.

    Insert

    53BP1(1-1710) 3LA7A (TP53BP1 Human)
    

    Use

    Retroviral

    Tags

    Flag tag, HA tag, and tetracysteine tag

    Expression

    Mammalian

    Mutation

    T302A, S452A, S523A, S543A, S625A, S784A, and S89…

    Promoter

    SV40

    Available Since

    July 1, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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12. shERK2b-mlpx-puro

    Plasmid

    #65230

    Purpose

    encodes a shRNA against ERK2

    Depositor

    Gerardo Ferbeyre

    Article

    Deschenes-Simard et al Genes Dev. 2013 Apr 15;27(8):900-15. doi

    Insert

    shRNA against ERK2 (MAPK1 Human)
    

    Expression

    Mammalian

    Promoter

    PGK

    Available Since

    Aug. 12, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA4-deltaH-AMBRA1-3xFLAG

    Plasmid

    #174158

    Purpose

    Vector for expression of 3xFLAG-tagged truncated AMBRA1 that cannot bind DDB1 (aa 1-34 deleted)

    Depositor

    Julien Sage

    Article

    Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

    Insert

    AMBRA1 (AMBRA1 Human)
    

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Missing aa 1-34

    Promoter

    CMV

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCW57.1 KBTBD4 P311PP

    Plasmid

    #184625

    Purpose

    Doxycycline inducible lentiviral vector for N-terminal Flag tagged KBTBD4 P311PP expression in mammalian cells

    Depositor

    Vincenzo D'Angiolella

    Article

    Chen et al Cell Death Differ. 2022 Apr 4. pii: 10.1

    Insert

    N-terminal Flag tagged KBTBD4 P311PP (KBTBD4 Human)
    

    Use

    Lentiviral; Doxycycline inducible

    Expression

    Mammalian

    Mutation

    P311PP

    Promoter

    TRE promoter, Tet ON

    Available Since

    June 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCAG-mTHC

    Plasmid

    #112620

    Purpose

    expression plasmid with CAG promoter driving multicistronic cassette H2BmTeal_p2A_HygroR_p2A_CreERt2

    Depositor

    Stefan Heller

    Article

    Hartman et al Dev Biol. 2018 Sep 1. pii: S0012-1606(18

    Inserts

    H2B-mTFP1 (H2BC3 Anthozoa, Human)
    Hygrophosphotransferase
    Cre-ERT2 fusion protein
    

    Tags

    mTeal (mTFP1)

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    Oct. 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. pEN-L1-K2-L2

    Plasmid

    #80684

    Purpose

    Gateway Entry vector containing a temperature-sensitive mouse DHFR

    Depositor

    Nico Dissmeyer

    Article

    Faden et al Nat Commun. 2016 Jul 22;7:12202. doi: 10

    Inserts

    DHFR (Dhfr Mouse)
    DHFR (Dhfr Mustard Weed, Mouse)
    

    Use

    Synthetic Biology

    Tags

    3xHA

    Expression

    Bacterial, Insect, Mammalia…

    Mutation

    mouse DHFR with N-terminal Ubiquitin

    Available Since

    Aug. 16, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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17. pRetroX-TetOne-Puro-p62 deltaUBA

    Plasmid

    #204550

    Purpose

    Expresses p62 deltaUBA in a doxycycline-dependent manner in mammalian cells

    Depositor

    Masaaki Komatsu

    Article

    Kurusu et al Dev Cell. 2023 May 9:S1534-5807(23)00191

    Insert

    p62 (SQSTM1 Human)
    

    Use

    Retroviral

    Expression

    Mammalian

    Mutation

    deltaUBA

    Available Since

    Aug. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. pPB-cT3G-cERP2-KLF6

    Plasmid

    #192909

    Purpose

    Barcoded piggybac transposon vector with Dox-inducible expression of KLF6

    Depositor

    George Church

    Article

    Pierson Smela et al Elife. 2023 Feb 21;12:e83291. doi: 10.75

    Insert

    KLF6 (KLF6 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Promoter

    TET3G-miniCMV

    Available Since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pGL4.23 C3_7

    Plasmid

    #60293

    Purpose

    This plasmid contains a human pancreatic islet active enhancer, a minimal promoter and a luc2 gene.

    Depositor

    Jorge Ferrer

    Article

    Pasquali et al Nat Genet. 2014 Feb;46(2):136-43. doi: 1

    Insert

    SLC30A8 enhancer (SLC30A8 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mammalian

    Available Since

    Dec. 2, 2014

    Availability

    Academic Institutions and Nonprofits only

20. pVHC_PGKneoLox2DTA.2

    Plasmid

    #112622

    Purpose

    H2BVenus_p2A_HygroR_p2A_CreERt2 targeting plasmid with cloning sites ready for homology arms

    Depositor

    Stefan Heller

    Article

    Hartman et al Dev Biol. 2018 Sep 1. pii: S0012-1606(18

    Inserts

    H2B-Venus (H2BC3 Aequorea victoria, Human)
    Hygrophosphotransferase
    Cre-ERT2 fusion protein
    

    Use

    Cre/Lox and Mouse Targeting

    Tags

    Venus

    Promoter

    No Promoter

    Available Since

    Sept. 13, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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