We narrowed to 17,803 results for: ERG

1. ZAP70 gRNA (BRDN0001148252)

   Plasmid

   #77955

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ZAP70

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ZAP70 (ZAP70 )
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. non-targeting control gRNA (BRDN0001146436)

   Plasmid

   #80221

   Purpose

   3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   Non-targeting control gRNA
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   Aug. 30, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. non-targeting control gRNA (BRDN0001146476)

   Plasmid

   #80194

   Purpose

   3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   Non-targeting control gRNA
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   Aug. 30, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. hEBI3 pEF6-Flag (MJS_003)

   Plasmid

   #72491

   Purpose

   Expression of human EBI3 in mammalian cells (Flag tag)

   Depositor

   Matthew Sweet

   Article

   Ramnath et al Immunol Cell Biol. 2015 Oct;93(9):771-9.

   Insert

   EBI3 (EBI3 Human)
   

   Tags

   Flag

   Expression

   Mammalian

   Available Since

   Feb. 12, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. ULK2 gRNA (BRDN0001147288)

   Plasmid

   #77262

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ULK2

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ULK2 (ULK2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. pJSC228 - Bacterial expression plasmid for SpCas9 Cluster 2 variant

   Plasmid

   #101233

   Purpose

   Bacterial expression plasmid for SpCas9 Cluster 2 variant

   Depositor

   Jennifer Doudna, Keith Joung

   Article

   Chen et al Nature. 2017 Sep 20. doi: 10.1038/nature

   Insert

   SpCas9 variant G582A/V583A/E584A/D585A/N588A
   

   Tags

   10x His, MBP, and TEV site

   Expression

   Bacterial

   Mutation

   G582A, V583A, E584A, D585A and N588A

   Promoter

   T7

   Available Since

   Oct. 4, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. LSB-hsa-miR-26a-5p

   Plasmid

   #103379

   Purpose

   Used to sense miRNA activity using fluorescence based tools. hsa-miR-26a-5p target in 3' UTR of of mKate. miRNA activity can be measured by the repression of mKate2 relative to EBFP2 fluorescent proteins . Plasmid is inherently unstable; please see Depositor Comments

   Depositor

   Ron Weiss

   Article

   Gam et al Nat Commun. 2018 Jun 22;9(1):2430. doi:

   Insert

   hsa-miR-26a-5p target
   

   Use

   Synthetic Biology

   Expression

   Mammalian

   Promoter

   EF-1a

   Available Since

   Dec. 3, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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8. px458_2A_GFP_sgRNA_ELAVL2

   Plasmid

   #106107

   Purpose

   CRISPR knockout. Expresses Cas9, EGFP, and sgRNA targeting ELAVL2

   Depositor

   Thomas Tuschl

   Article

   Meyer et al Mol Cell. 2018 Feb 15;69(4):622-635.e6.

   Insert

   gRNA targeting ELAVL2 (ELAVL2 Human)
   

   Use

   CRISPR

   Available Since

   Feb. 12, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. ROR1 gRNA (BRDN0001162245)

   Plasmid

   #76043

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ROR1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ROR1 (ROR1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. VRK1 gRNA (BRDN0001147568)

    Plasmid

    #75522

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human VRK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    VRK1 (VRK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. VRK1 gRNA (BRDN0001148483)

    Plasmid

    #75523

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human VRK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    VRK1 (VRK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. LSB-hsa-miR-125b-5p

    Plasmid

    #103191

    Purpose

    Used to sense miRNA activity using fluorescence based tools. hsa-miR-125b-5p target in 3' UTR of of mKate. miRNA activity can be measured by the repression of mKate2 relative to EBFP2 fluorescent proteins . Plasmid is inherently unstable; please see Depositor Comments

    Depositor

    Ron Weiss

    Article

    Gam et al Nat Commun. 2018 Jun 22;9(1):2430. doi:

    Insert

    hsa-miR-125b-5p target
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Promoter

    EF-1a

    Available Since

    Nov. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. STK33 gRNA (BRDN0001149402)

    Plasmid

    #76984

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human STK33

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    STK33 (STK33 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. XE254 pCDNA3.1(zeo)-hDsh3-497-716

    Plasmid

    #16755

    Depositor

    Randall Moon

    Article

    Angers et al Nat Cell Biol. 2006 Apr . 8(4):348-57.

    Insert

    FLAG-497-716-Dsh3 (DVL3 Human)
    

    Tags

    flag

    Expression

    Mammalian

    Mutation

    aa 497-716

    Available Since

    March 14, 2008

    Availability

    Academic Institutions and Nonprofits only

    

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15. Sox2-SE-RGM-eGFP targeting vector

    Plasmid

    #133045

    Purpose

    Targeting vector of RGM-eGFP with homologous arms around Sox2 super-enhancer DMR

    Depositor

    Rudolf Jaenisch

    Article

    Song et al Mol Cell. 2019 Aug 15. pii: S1097-2765(1

    Insert

    Sox2-SE-5arm-RGM-Sox2-SE-3arm
    

    Use

    Mouse Targeting

    Available Since

    Nov. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. TRIM27 gRNA (BRDN0001148850)

    Plasmid

    #77517

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TRIM27

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TRIM27 (TRIM27 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pCDNA3 T7 Jip1(delta JBD)

    Plasmid

    #51767

    Purpose

    " JIP-1 may suppress signal transduction by the JNK pathway"

    Depositor

    Roger Davis

    Article

    Dickens et al Science. 1997 Aug 1. 277(5326):693-6.

    Insert

    Jnk interacting protein 1 (Mapk8ip1 Mouse)
    

    Tags

    T7

    Expression

    Mammalian

    Mutation

    deleted 126-263

    Available Since

    March 14, 2014

    Availability

    Academic Institutions and Nonprofits only

18. RIPK3 gRNA (BRDN0001148666)

    Plasmid

    #76999

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human RIPK3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    RIPK3 (RIPK3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. Gal4-entry

    Plasmid

    #128014

    Purpose

    Vector containing the Gal4-entry expression cassette and a separate expression cassette driving mCherry via the traffic jam enhancer

    Depositor

    Julius Brennecke

    Article

    Batki et al Nat Struct Mol Biol. 2019 Aug;26(8):720-

    Insert

    Gal4-DBD-3xFlag
    

    Use

    Gal4 entry vector

    Tags

    Gal4-DBD-3xFlag

    Available Since

    Aug. 2, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. p3E-DysF

    Plasmid

    #109544

    Purpose

    Multisite gateway vector for 3' tagging with Dysferlin

    Depositor

    Rob Parton

    Article

    Hall et al Nat Commun. 2020 Jul 24;11(1):3711. doi:

    Insert

    Dysferlin (dysf Zebrafish)
    

    Use

    Zebrafish plasmids

    Mutation

    Please see Depositor Comments

    Available Since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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