We narrowed to 9,972 results for: crispr plasmids

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pLEW100v5-NEO-T7-sgRNA

Plasmid

#245118

Purpose

Plasmid backbone to for inserting a T7 promoter driven guide RNA into the rDNA spacer of T. brucei

Depositor

Monica Mugnier

Article

Smith et al Nature. 2026 Apr 8. doi: 10.1038/s41586-

Type

Empty backbone

Use

CRISPR

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pX459-TMEM217-gRNA#2

Plasmid

#249418

Purpose

pX459 plasmid containing gRNA#2 targeting the end of the coding exon of human TMEM217

Depositor

Masahito Ikawa

Article

Iida-Norita et al Proc Natl Acad Sci U S A. 2025 Oct 21;12

Insert

TMEM217 (TMEM217 Human)

Use

CRISPR

Available Since

Feb. 25, 2026

Availability

Academic Institutions and Nonprofits only

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pCMVp_eGFP

Plasmid

#241002

Purpose

For targeted gene knock-in at NHP IGH locus and constitutive expression of GFP

Depositor

Jennifer Adair

Article

Castelli et al Mol Ther. 2026 Feb 2:S1525-0016(26)00081

Insert

eGFP (eGFP Synthetic)

Use

AAV and CRISPR

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 10, 2026

Availability

Academic Institutions and Nonprofits only

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pVH4p_eGFP

Plasmid

#241003

Purpose

For targeted gene knock-in at NHP IGH locus and B cell-specific expression of GFP

Depositor

Jennifer Adair

Article

Castelli et al Mol Ther. 2026 Feb 2:S1525-0016(26)00081

Insert

eGFP (eGFP )

Use

AAV and CRISPR

Expression

Mammalian

Promoter

VH4

Available Since

Feb. 10, 2026

Availability

Academic Institutions and Nonprofits only

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px-458-sgRNA-IF1

Plasmid

#206923

Purpose

Plasmid expressing Cas9, GFP and guides to human IF1 to generate IF1-KO mammalian cell lines

Depositor

José Cuezva

Article

Romero-Carraminana et al Commun Biol. 2023 Aug 12;6(1):836. doi:

Insert

sgRNA targeting IF1 (ATPase inhibitory factor 1) (ATP5IF1 Human)

Use

CRISPR

Promoter

U6

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab966-pUC19-HAL-BRCA1-BSD-P2A-2xHA-FKBP12-F36V-HAR-BRCA1

Plasmid

#249004

Purpose

This plasmid expresses the degron tag knock-in sequence at the N-terminus of the endogenous BRCA1 locus

Depositor

Georgios Karras

Article

Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086

Insert

FKBP12 (FKBP1A Human)

Use

CRISPR

Tags

2xHA

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pLCHKOv4

Plasmid

#237451

Purpose

Lentiviral backbone for expressing U6-driven hybrid guide (hg)RNAs for scCHyMErA-Seq experiments.

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Type

Empty backbone

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pLCHKOv5

Plasmid

#237452

Purpose

Lentiviral backbone for expressing doxycycline (Dox)-inducible, Pol II-driven hybrid guide (hg)RNAs.

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Type

Empty backbone

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pTarget-TTC

Plasmid

#246930

Purpose

for E.coli plasmid interference and PAM depletion assays

Depositor

Caixia Gao

Article

Jin et al Cell. 2025 Sep 29:S0092-8674(25)01035-9.

Insert

TTC PAM and GFP-T1 target

Use

Unspecified

Available Since

Nov. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pX330_mouseH3.1

Plasmid

#244241

Purpose

Expresses SpCas9 and a sgRNA targeting the mouse histone H3.1 loci for knock-in.

Depositor

Kazuhiro Maeshima

Article

Minami et al Sci Adv. 2025 Mar 28;11(13):eadu8400. do

Insert

sgRNA targeting mouse histone H3.1 (H3c1 Mouse)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Oct. 7, 2025

Availability

Academic Institutions and Nonprofits only

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pX330_H3.2

Plasmid

#244239

Purpose

Expresses SpCas9 and a sgRNA targeting the human histone H3.2 loci for knock-in.

Depositor

Kazuhiro Maeshima

Article

Minami et al Sci Adv. 2025 Mar 28;11(13):eadu8400. do

Insert

sgRNA targeting human histone H3.2 (H3C14, H3C15 Human)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Oct. 7, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-U6-DR30(SapI)-CMV-intron-MCS-pA

Plasmid

#192496

Purpose

To express CasRX gRNA and contains MCS to insert coding region of interest

Depositor

Jonathan Ploski

Article

Back et al Mol Ther Methods Clin Dev. 2025 Aug 20;3

Insert

CasRx

Use

AAV

Mutation

No

Promoter

CMV

Available Since

Aug. 27, 2025

Availability

Academic Institutions and Nonprofits only

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pX601-AAV-CMV-NLS-SaCas9-NLS-3xHA-bGHpA;U6-Cre-2

Plasmid

#237891

Purpose

Cre-KO AAV vector#2 containing SaCas9 and its sgRNA targeting Cre

Depositor

Rui Lin

Article

Zhong et al Neuron. 2025 Sep 18:S0896-6273(25)00657-

Insert

sgRNA-Cre

Use

AAV and CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Aug. 25, 2025

Availability

Academic Institutions and Nonprofits only

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pX601-AAV-CMV-NLS-SaCas9-NLS-3xHA-bGHpA;U6-Cre-3

Plasmid

#237892

Purpose

Cre-KO AAV vector#3 containing SaCas9 and its sgRNA targeting Cre

Depositor

Rui Lin

Article

Zhong et al Neuron. 2025 Sep 18:S0896-6273(25)00657-

Insert

sgRNA-Cre

Use

AAV and CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Aug. 25, 2025

Availability

Academic Institutions and Nonprofits only

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pdU6-2_sgRNA-d5-HT1AR

Plasmid

#221820

Purpose

Plasmid to express gRNA (gaccagtccactaccgcagc) for editing at the end of Drosophila 5-HT1AR coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT1AR gRNA (5-HT1A Fly)

Use

CRISPR

Expression

Insect

Promoter

zebrafish U6 promoter (U6b)

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pdU6-2_sgRNA1-d5-HT1BR

Plasmid

#221821

Purpose

Plasmid to express gRNA1 (gaaaatttgatttcaactga) for editing at the end of Drosophila 5-HT1BR coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT1BR gRNA1 (5-HT1B Fly)

Use

CRISPR

Expression

Insect

Promoter

zebrafish U6 promoter (U6b)

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pdU6-2_sgRNA2-5-HT1BR

Plasmid

#221822

Purpose

Plasmid to express gRNA2 (aatttcgacgggccttcaag) for editing at the end of Drosophila 5-HT1BR coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT1BR gRNA2 (5-HT1B Fly)

Use

CRISPR

Expression

Insect

Promoter

Drosophila U6 promoter

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pdU6-2_sgRNA1-5-HT2AR-isoformD

Plasmid

#221823

Purpose

Plasmid to express gRNA1 (tccttctggcgcaaacacgg) for editing at the end of Drosophila 5-HT2AR isoform D coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT2AR isoform D gRNA1 (5-HT2 Fly)

Use

CRISPR

Expression

Insect

Promoter

Drosophila U6 promoter

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pdU6-2_sgRNA2-5-HT2AR-isoformD

Plasmid

#221824

Purpose

Plasmid to express gRNA2 (ctgaagacataattacgtgg) for editing at the end of Drosophila 5-HT2AR isoform D coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT2AR isoform D gRNA2 (5-HT2 Fly)

Use

CRISPR

Expression

Insect

Promoter

zebrafish U6 promoter (U6b)

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pdU6-2_sgRNA1-5-HT2AR-isoformBFH

Plasmid

#221825

Purpose

Plasmid to express gRNA1 (cgctatcggtctgtgacaga) for editing at the end of Drosophila 5-HT2AR isoforms B, F and H coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT2AR isoforms BFH gRNA1 (5-HT2 Fly)

Use

CRISPR

Expression

Insect

Promoter

zebrafish U6 promoter (U6b)

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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