We narrowed to 4,936 results for: AAT

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pdU6-2_sgRNA2-5-HT1BR

Plasmid

#221822

Purpose

Plasmid to express gRNA2 (aatttcgacgggccttcaag) for editing at the end of Drosophila 5-HT1BR coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT1BR gRNA2 (5-HT1B Fly)

Use

CRISPR

Expression

Insect

Promoter

Drosophila U6 promoter

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pdU6-2_sgRNA2-5-HT2AR-isoformD

Plasmid

#221824

Purpose

Plasmid to express gRNA2 (ctgaagacataattacgtgg) for editing at the end of Drosophila 5-HT2AR isoform D coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT2AR isoform D gRNA2 (5-HT2 Fly)

Use

CRISPR

Expression

Insect

Promoter

zebrafish U6 promoter (U6b)

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pdU6-2_sgRNA2-5-HT2AR-isoformBFH

Plasmid

#221826

Purpose

Plasmid to express gRNA2 (ggaaaagccgctaattacag) for editing at the end of Drosophila 5-HT2AR isoforms B, F and H coding frame

Depositor

Quentin Gaudry

Article

Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

Insert

d5-HT2AR isoforms BFH gRNA2 (5-HT2 Fly)

Use

CRISPR

Expression

Insect

Promoter

Drosophila U6 promoter

Available Since

Aug. 18, 2025

Availability

Academic Institutions and Nonprofits only

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PX459_NRF2-exon5-1

Plasmid

#177781

Purpose

sgRNA for CRISPR/Cas9-mediated deletion of human NRF2

Depositor

Michael Ristow

Article

Thomas et al Nat Commun. 2023 Dec 8;14(1):8142. doi:

Insert

NRF2 (NFE2L2 Human)

Use

CRISPR

Available Since

Aug. 6, 2025

Availability

Academic Institutions and Nonprofits only

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PX459_NRF2-exon5-2

Plasmid

#177782

Purpose

sgRNA for CRISPR/Cas9-mediated deletion of human NRF2

Depositor

Michael Ristow

Article

Thomas et al Nat Commun. 2023 Dec 8;14(1):8142. doi:

Insert

NRF2 (NFE2L2 Human)

Use

CRISPR

Available Since

Aug. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pk335-CARGO-6mer-14kb-USF-1-6

Plasmid

#227470

Purpose

6-mer gRNA array targeting Sp dCas9/Cas9 to the Prdm8-Fgf5 locus

Depositor

Joanna Wysocka

Article

Jensen et al Mol Cell. 2025 Jan 16;85(2):347-361.e7.

Insert

CARGO to 14kb Upstream Fgf5

Use

CRISPR

Available Since

May 5, 2025

Availability

Academic Institutions and Nonprofits only

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pk335-CARGO-6mer-14kb-USF-7-12

Plasmid

#227471

Purpose

6-mer gRNA array targeting Sp dCas9/Cas9 to the Prdm8-Fgf5 locus

Depositor

Joanna Wysocka

Article

Jensen et al Mol Cell. 2025 Jan 16;85(2):347-361.e7.

Insert

CARGO to 14kb Upstream Fgf5

Use

CRISPR

Available Since

May 5, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pk335-CARGO-6mer-700bp-USF

Plasmid

#227478

Purpose

6-mer gRNA array targeting Sp dCas9/Cas9 to the Prdm8-Fgf5 locus

Depositor

Joanna Wysocka

Article

Jensen et al Mol Cell. 2025 Jan 16;85(2):347-361.e7.

Insert

CARGO to 700bp Upstream Fgf5

Use

CRISPR

Available Since

May 5, 2025

Availability

Academic Institutions and Nonprofits only

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pk335-CARGO-6mer-58kb-USF

Plasmid

#227457

Purpose

6-mer gRNA array targeting Sp dCas9/Cas9 to the Prdm8-Fgf5 locus

Depositor

Joanna Wysocka

Article

Jensen et al Mol Cell. 2025 Jan 16;85(2):347-361.e7.

Insert

CARGO to 58kb Upstream Fgf5

Use

CRISPR

Available Since

May 5, 2025

Availability

Academic Institutions and Nonprofits only

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pk335-CARGO-6mer-20kb-USP

Plasmid

#227446

Purpose

6-mer gRNA array targeting Sp dCas9/Cas9 to the Prdm8-Fgf5 locus

Depositor

Joanna Wysocka

Article

Jensen et al Mol Cell. 2025 Jan 16;85(2):347-361.e7.

Insert

CARGO to 20kb Upstream Prdm8

Use

CRISPR

Available Since

May 5, 2025

Availability

Academic Institutions and Nonprofits only

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pAPM-miR30-ILF2-ts2

Plasmid

#174263

Purpose

ILF2 knockdown

Depositor

Jeremy Luban

Article

Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

Insert

ILF2 shRNA (ILF2 Human)

Use

Lentiviral and RNAi

Promoter

SFFV

Available Since

Aug. 27, 2024

Availability

Academic Institutions and Nonprofits only

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pAPM-miR30-DDX58-ts2

Plasmid

#174242

Purpose

DDX58 knockdown

Depositor

Jeremy Luban

Article

Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

Insert

DDX58 shRNA (RIGI Human)

Use

Lentiviral and RNAi

Promoter

SFFV

Available Since

Aug. 27, 2024

Availability

Academic Institutions and Nonprofits only

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TLNRD1(4H)-2T_pET47b

Plasmid

#224069

Purpose

Bacterial expression of the 4-helix bundle of TLNRD1 (residues 143-273) containing the mutations L191T/A225T, fused to an N-terminal hexa-histidine tag. HRV-3C cleavage site

Depositor

Ben Goult

Article

Ball et al J Cell Biol. 2024 Sep 2;223(9):e20231003

Insert

tlnrd1 (TLNRD1 Human)

Tags

6xHIS

Expression

Bacterial

Mutation

L191T/A225T double mutant; reduces affinity of TL…

Promoter

T7

Available Since

Aug. 26, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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TLNRD1(4H)-2E_pET151

Plasmid

#224068

Purpose

Bacterial expression of the 4-helix bundle of TLNRD1 (residues 143-273) containing the mutations K192E/R233E, fused to an N-terminal hexa-histidine tag. TEV cleavage site

Depositor

Ben Goult

Article

Ball et al J Cell Biol. 2024 Sep 2;223(9):e20231003

Insert

tlnrd1 (TLNRD1 Human)

Tags

6xHIS; V5

Expression

Bacterial

Mutation

K192E/R233E double mutant; prevents actin binding…

Promoter

T7

Available Since

Aug. 26, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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AA244

Plasmid

#215945

Purpose

Fragmid fragment: (guide cassette) guide expression; positive control cell surface

Depositor

John Doench

Article

McGee et al Cell Genom. 2024 Mar 13;4(3):100519. doi

Has Service

Cloning Grade DNA

Insert

U6_v1; sgCD59_v1 [Sp]; trRNA_v4 [Sp]

Use

CRISPR; Fragment

Available Since

April 29, 2024

Availability

Academic Institutions and Nonprofits only

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U6-sgRNA-pcr4

Plasmid

#193662

Purpose

Expression of tandem pre-sgRNA array pcr4 for LbCas12a

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

U6-PUM1-sgRNA-GHR-sgRNA-HMGA2-sgRNA-PUM2-sgRNA-tRNA

Expression

Mammalian

Promoter

U6

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

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CCM2_I432D_eGFP

Plasmid

#208879

Purpose

Express eGFP-CCM2 with the I432D mutation in mammalian cells.

Depositor

Guillaume Jacquemet

Article

Ball et al J Cell Biol. 2024 Sep 2;223(9):e20231003

Insert

CCM2 (CCM2 Human)

Tags

eGFP

Expression

Mammalian

Mutation

mutation I432D

Available Since

Dec. 22, 2023

Availability

Academic Institutions and Nonprofits only

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CCM2_W421AD422A_eGFP

Plasmid

#208880

Purpose

Express eGFP-CCM2 with the W421A and D422A mutations in mammalian cells.

Depositor

Guillaume Jacquemet

Article

Ball et al J Cell Biol. 2024 Sep 2;223(9):e20231003

Insert

CCM2 (CCM2 Human)

Tags

eGFP

Expression

Mammalian

Mutation

mutations W421A and D422A

Available Since

Dec. 22, 2023

Availability

Academic Institutions and Nonprofits only

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CCM2_I428S_eGFP

Plasmid

#208878

Purpose

Express eGFP-CCM2 with the I428S mutation in mammalian cells.

Depositor

Guillaume Jacquemet

Article

Ball et al J Cell Biol. 2024 Sep 2;223(9):e20231003

Insert

CCM2 (CCM2 Human)

Tags

eGFP

Expression

Mammalian

Mutation

mutation I428S

Available Since

Dec. 22, 2023

Availability

Academic Institutions and Nonprofits only

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LENTICRISPR-PGM2_sgRNA1

Plasmid

#201616

Purpose

CRISPR/Cas9-mediated gene knock-out

Depositor

Alexis Jourdain, Vamsi Mootha

Article

Skinner et al Nat Metab. 2023 May;5(5):765-776. doi: 1

Insert

PGM2 (PGM2 Human)

Use

CRISPR and Lentiviral

Available Since

July 26, 2023

Availability

Academic Institutions and Nonprofits only

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