We narrowed to 4,522 results for: GCA;

Showing: 1531 - 1560 of 4522 results

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sgNF2

Plasmid

#229433

Purpose

knockout of NF2

Depositor

Christopher Vakoc

Article

Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

Insert

sgNF2 (NF2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6;bU6;EFS

Available Since

Jan. 10, 2025

Availability

Academic Institutions and Nonprofits only

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KU70-eGFP-SUN1ΔN

Plasmid

#213516

Purpose

Expresses human KU70-eGFP-SUN1ΔN in mammalian cells

Depositor

Karim Mekhail

Article

Shokrollahi et al Nat Struct Mol Biol. 2024 Sep;31(9):1319

Insert

KU70-eGFP-SUNΔN

Expression

Mammalian

Mutation

SUN1ΔN has the first 138 amino acid (lamina domai…

Promoter

CMV

Available Since

May 15, 2024

Availability

Academic Institutions and Nonprofits only

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LMPd Amt PHGDH

Plasmid

#209409

Purpose

Retroviral vector with Ametrine marker for expressing shRNA with an "UltramiR" microRNA scaffold

Depositor

Russell Jones

Article

Ma et al Immunity. 2019 Nov 19;51(5):856-870.e5.

Insert

Phgdh shRNA (Phgdh Mouse)

Use

Retroviral

Available Since

May 7, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(ARID2(14))-PGKpuro2ABFP-W

Plasmid

#200472

Purpose

Lentiviral vector expressing gRNA targeting human ARID2

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

ARID2(14) (ARID2 Human)

Use

Lentiviral

Available Since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CMV-FLEX-SaCas9-U6-sgFAAH

Plasmid

#209197

Purpose

Mutagenesis of Faah

Depositor

Larry Zweifel

Article

Balsevich et al Elife. 2023 Apr 11;12:e81919. doi: 10.75

Insert

Faah (Faah Mouse)

Use

AAV, CRISPR, and Mouse Targeting

Promoter

CMV

Available Since

Jan. 3, 2024

Availability

Academic Institutions and Nonprofits only

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pSpdCas9-huTET1CD-T2A-mCherry(PX458)-SghuTSDR-6

Plasmid

#129034

Purpose

targeted DNA demethylation_human_TSDR, expression of dCas9-huTET1CD-T2A-mCherry and sgRNA6 targeting human TSDR

Depositor

Julia K Polansky

Article

Kressler et al Front Immunol. 2021 Jan 7;11:609891. doi

Insert

dCas9-huTET1CD, SgRNA6 (huTSDR)

Tags

HA-Tag, NLS and T2A-mCherry

Expression

Mammalian

Mutation

dCas9 (D10A;H840A)

Promoter

CbH (for dCas9-huTET1CD-T2A-EGFP) U6 (for sgRNA)

Available Since

Jan. 25, 2021

Availability

Academic Institutions and Nonprofits only

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AOI-WT-Cas9-sg-mouse Gfi1-exon4(F1)-GFP

Plasmid

#91883

Purpose

Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Gfi1

Depositor

Martine Roussel

Article

Vo et al Cell Rep. 2017 Mar 21;18(12):2907-2917.

Insert

gRNA targeting Gfi1 (Gfi1 Mouse)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

June 26, 2017

Availability

Academic Institutions and Nonprofits only
CROT gRNA (BRDN0001145682)

Plasmid

#77709

Purpose

3rd generation lentiviral gRNA plasmid targeting human CROT

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CROT (CROT Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 18, 2016

Availability

Academic Institutions and Nonprofits only

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C17orf75 gRNA (BRDN0001487133)

Plasmid

#78079

Purpose

3rd generation lentiviral gRNA plasmid targeting human C17orf75

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

C17orf75 (C17orf75 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CDK18 gRNA (BRDN0001144740)

Plasmid

#77880

Purpose

3rd generation lentiviral gRNA plasmid targeting human CDK18

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CDK18 (CDK18 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ARSG gRNA (BRDN0001148698)

Plasmid

#77642

Purpose

3rd generation lentiviral gRNA plasmid targeting human ARSG

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ARSG (ARSG Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IP6K3 gRNA (BRDN0001147058)

Plasmid

#77654

Purpose

3rd generation lentiviral gRNA plasmid targeting human IP6K3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IP6K3 (IP6K3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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AATK gRNA (BRDN0001146583)

Plasmid

#77315

Purpose

3rd generation lentiviral gRNA plasmid targeting human AATK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

AATK (AATK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP3K9 gRNA (BRDN0001145934)

Plasmid

#77310

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP3K9

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP3K9 (MAP3K9 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DCLK3 gRNA (BRDN0001147290)

Plasmid

#77313

Purpose

3rd generation lentiviral gRNA plasmid targeting human DCLK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DCLK3 (DCLK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DGKD gRNA (BRDN0001148084)

Plasmid

#77259

Purpose

3rd generation lentiviral gRNA plasmid targeting human DGKD

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DGKD (DGKD Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CAMK4 gRNA (BRDN0001146440)

Plasmid

#77224

Purpose

3rd generation lentiviral gRNA plasmid targeting human CAMK4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CAMK4 (CAMK4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HIPK3 gRNA (BRDN0001146408)

Plasmid

#77032

Purpose

3rd generation lentiviral gRNA plasmid targeting human HIPK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HIPK3 (HIPK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DGKB gRNA (BRDN0001146143)

Plasmid

#76918

Purpose

3rd generation lentiviral gRNA plasmid targeting human DGKB

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DGKB (DGKB Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DLG1 gRNA (BRDN0001145356)

Plasmid

#76619

Purpose

3rd generation lentiviral gRNA plasmid targeting human DLG1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DLG1 (DLG1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DGUOK gRNA (BRDN0001148589)

Plasmid

#76604

Purpose

3rd generation lentiviral gRNA plasmid targeting human DGUOK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DGUOK (DGUOK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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AK2 gRNA (BRDN0001146723)

Plasmid

#76580

Purpose

3rd generation lentiviral gRNA plasmid targeting human AK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

AK2 (AK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CKB gRNA (BRDN0001145509)

Plasmid

#76589

Purpose

3rd generation lentiviral gRNA plasmid targeting human CKB

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CKB (CKB Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CDK19 gRNA (BRDN0001148326)

Plasmid

#76505

Purpose

3rd generation lentiviral gRNA plasmid targeting human CDK19

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CDK19 (CDK19 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ADCK1 gRNA (BRDN0001149367)

Plasmid

#76087

Purpose

3rd generation lentiviral gRNA plasmid targeting human ADCK1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ADCK1 (ADCK1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CMPK2 gRNA (BRDN0001147027)

Plasmid

#75806

Purpose

3rd generation lentiviral gRNA plasmid targeting human CMPK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CMPK2 (CMPK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CSNK2A2 gRNA (BRDN0001147190)

Plasmid

#75587

Purpose

3rd generation lentiviral gRNA plasmid targeting human CSNK2A2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CSNK2A2 (CSNK2A2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ETNK1 gRNA (BRDN0001148358)

Plasmid

#75532

Purpose

3rd generation lentiviral gRNA plasmid targeting human ETNK1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ETNK1 (ETNK1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2 puro - CRBN (#2)

Plasmid

#166241

Purpose

sgRNA (#2) to generate a knockout of human CRBN by targeting the start region of Exon1

Depositor

Günter Schneider

Article

Lier et al Bioorg Chem. 2021 Nov 20:105505. doi: 10

Insert

CRBN (CRBN Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

Dec. 20, 2021

Availability

Academic Institutions and Nonprofits only

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pLV-shFMR1-mCherry

Plasmid

#222963

Purpose

Make lentivirus to knock down human FMR1 gene

Depositor

Xinyu Zhao

Article

Guo et al Nat Commun. 2023 Jun 26;14(1):3801. doi:

Insert

FMR1 shRNA (FMR1 Human)

Use

Lentiviral

Available Since

Oct. 17, 2024

Availability

Academic Institutions and Nonprofits only

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