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pBrain-GFP-TACC3KDP∆678-681-shTACC3

Plasmid

#69115

Purpose

Dual-promoter plasmid to express knockdown-proof human TACC3 (amino acids 678-681 deleted) tagged with EGFP along with shRNA to knock down endogenous TACC3 in mammalian cells.

Depositor

Stephen Royle

Article

Gutierrez-Caballero et al Biol Open. 2015 Jan 16;4(2):170-9. doi:

Inserts

Transforming Acidic Coiled Coil protein 3 (TACC3 Human)
shTACC3

Use

RNAi

Tags

EGFP

Expression

Mammalian

Mutation

Deletion of 678-681aa region. Silent mutations i…

Promoter

CMV

Available Since

Oct. 6, 2015

Availability

Academic Institutions and Nonprofits only

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pFB-Flag-MyoD(QQQ)-E12

Plasmid

#26003

Depositor

Jeffrey Dilworth

Article

Dilworth et al Proc Natl Acad Sci U S A. 2004 Aug 10. 1

Insert

MyoD(QQQ)-E12 Heterodimer Fusion (Myod1 Mouse)

Use

Baculovirus transfer vector

Tags

Flag

Mutation

Changed Lysine 99 to Glutamine; Lysine 102 to Glu…

Available Since

Sept. 8, 2010

Availability

Academic Institutions and Nonprofits only

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xylt1_L (OZ509)

Plasmid

#27184

Depositor

Keith Joung

Article

Maeder et al Mol Cell. 2008 Jul 25. 31(2):294-301.

Insert

Zinc finger array targeting xylt1 (xylt1 Zebrafish)

Use

Zebrafish targeting

Available Since

Jan. 25, 2011

Availability

Academic Institutions and Nonprofits only
pcDNA 3.3 N-MYC ATP6V1G1

Plasmid

#246137

Purpose

Used for transfection of cells for expression N-MYC ATP6V1G1

Depositor

Sheng-cai Lin

Article

Qu et al Nature. 2024 Dec 18. doi: 10.1038/s41586

Insert

ATP6V1G1 (ATP6 Human)

Tags

MYC

Expression

Mammalian

Available Since

April 21, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-MYC ATP6V1D

Plasmid

#246133

Purpose

Used for transfection of cells for expression N-MYC ATP6V1D

Depositor

Sheng-cai Lin

Article

Qu et al Nature. 2024 Dec 18. doi: 10.1038/s41586

Insert

ATP6V1D (ATP6 Human)

Tags

MYC

Expression

Mammalian

Available Since

April 21, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-MYC ATP6V1B2

Plasmid

#246130

Purpose

Used for transfection of cells for expression N-MYC ATP6V1B2

Depositor

Sheng-cai Lin

Article

Qu et al Nature. 2024 Dec 18. doi: 10.1038/s41586

Insert

ATP6V1B2 (ATP6 Human)

Tags

MYC

Expression

Mammalian

Available Since

April 21, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-MYC ATP6V1A

Plasmid

#246129

Purpose

Used for transfection of cells for expression N-MYC ATP6V1A

Depositor

Sheng-cai Lin

Article

Qu et al Nature. 2024 Dec 18. doi: 10.1038/s41586

Insert

ATP6V1A (ATP6 Human)

Tags

MYC

Expression

Mammalian

Available Since

April 21, 2026

Availability

Academic Institutions and Nonprofits only

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pCAGGS-GFP-WTUBA7-IRES-mcherry

Plasmid

#246475

Purpose

Mammalian expression of AcGFP-tagged WT human UBA7, co-expresses mCherry; for transfection

Depositor

Francisco Bustos

Article

Bandi et al iScience 2026. doi: 10.1016/j.isci.2026.

Insert

AcGFP-WTUBA7-IRES-mcherry (UBA7 Human)

Tags

AcGFP1

Expression

Mammalian

Available Since

April 1, 2026

Availability

Academic Institutions and Nonprofits only

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pCAGGS-GFP-UBA7-V548L-IRES-mcherry

Plasmid

#246476

Purpose

Mammalian expression of AcGFP-tagged human UBA7-V548L, co-expresses mCherry; for transfection

Depositor

Francisco Bustos

Article

Bandi et al iScience 2026. doi: 10.1016/j.isci.2026.

Insert

AcGFP-UBA7-V548L-IRES-mcherry (UBA7 Human)

Tags

AcGFP1

Expression

Mammalian

Mutation

V548L

Available Since

April 1, 2026

Availability

Academic Institutions and Nonprofits only

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pCAGGS-GFP-UBA7-K709Sfs-IRES-mcherry

Plasmid

#246477

Purpose

Mammalian expression of AcGFP-tagged human UBA7-K709Sfs, co-expresses mCherry; for transfection

Depositor

Francisco Bustos

Article

Bandi et al iScience 2026. doi: 10.1016/j.isci.2026.

Insert

AcGFP-UBA7-K709S*fs-IRES-mcherry (UBA7 Human)

Tags

AcGFP1

Expression

Mammalian

Mutation

K709Sfs*

Available Since

April 1, 2026

Availability

Academic Institutions and Nonprofits only

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pscAAV- EF1α core -hKCNJ2-HA tag

Plasmid

#246995

Purpose

Can be used to generate AAV virus that will express human KCNJ2 with Ala115 HA tag from EF1α core promoter

Depositor

Ting Chen

Article

Chen et al Cell. 2025 Aug 14:S0092-8674(25)00857-8.

Insert

hKCNJ2 (KCNJ2 Human)

Use

AAV

Tags

HA tag (Internal at Ala115)

Promoter

EF1α

Available Since

March 11, 2026

Availability

Academic Institutions and Nonprofits only

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pscAAV-U6-gTgfbr2-CBh-mCherry-SV40late

Plasmid

#249125

Purpose

expression of gTgfbr2 and mCherry

Depositor

Matthew Krummel

Article

Kuhn et al J Exp Med. 2026 May 4;223(5):e20251228.

Insert

gTgfbr2 (Tgfbr2 Mouse)

Use

AAV

Promoter

hU6

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pscAAV-U6-gThy1-CBh-mCherry-SV40late

Plasmid

#249126

Purpose

expression of gThy1 and mCherry

Depositor

Matthew Krummel

Article

Kuhn et al J Exp Med. 2026 May 4;223(5):e20251228.

Insert

gThy1 (Thy1 Mouse)

Use

AAV

Promoter

hU6

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pscAAV-KIKO-U6-gOsmr-p2a-mCherry-STOP-pA-400

Plasmid

#249130

Purpose

all-in-one HDRT-based knockin-knockout (KIKO) design to insert mCherry (=knockin) at gOsmr cut site, disrupting Osmr expression

Depositor

Matthew Krummel

Article

Kuhn et al J Exp Med. 2026 May 4;223(5):e20251228.

Insert

gOsmr, mCherry (Osmr Mouse, Synthetic)

Use

AAV

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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synapsin-hIRβ

Plasmid

#236226

Purpose

Expressing a truncated, constitutively active human insulin receptor (IRβ) in neurons

Depositor

Olivier Thibault

Article

Frazier et al Neurochem Res. 2019 Jan;44(1):269-280. d

Insert

human Insulin Receptor beta subunit (INSR Human)

Use

AAV

Expression

Bacterial

Promoter

neuron-specific synapsin promote

Available Since

Feb. 13, 2026

Availability

Academic Institutions and Nonprofits only

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pVH4p_3BNC117_muSplice

Plasmid

#241004

Purpose

For targeted gene knock-in at NHP IGH locus and B cell-specific expression of full-length 3BNC117 following endogenous splicing

Depositor

Jennifer Adair

Article

Castelli et al Mol Ther. 2026 Feb 2:S1525-0016(26)00081

Insert

3BNC117

Use

AAV and CRISPR

Expression

Mammalian

Promoter

VH4

Available Since

Feb. 10, 2026

Availability

Academic Institutions and Nonprofits only

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pVH4p_10-1074_muSplice

Plasmid

#241005

Purpose

For targeted gene knock-in at NHP IGH locus and B cell-specific expression of full-length 10-1074 following endogenous splicing

Depositor

Jennifer Adair

Article

Castelli et al Mol Ther. 2026 Feb 2:S1525-0016(26)00081

Insert

10-1074

Use

AAV and CRISPR

Expression

Mammalian

Promoter

VH4

Available Since

Feb. 10, 2026

Availability

Academic Institutions and Nonprofits only

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AAV-CaMKIIα-optoFGFR1-HA

Plasmid

#250236

Purpose

AAV expressing light-activatable FGFR1 (optoFGFR1-HA) under the CaMKIIα promoter for excitatory-neuron-specific activation

Depositor

Won Do Heo

Article

Shin et al Exp Mol Med. 2025 Aug;57(8):1818-1836. d

Insert

FGFR1 (FGFR1 Human)

Use

AAV

Expression

Mammalian

Promoter

CamKIIα

Available Since

Jan. 16, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-GfaABC1D-mSLF-Myc-His

Plasmid

#249179

Purpose

AAV mediated overexpression of C-terminal fragment of mouse Sparcl1

Depositor

Cagla Eroglu

Article

Ramirez et al Neuron. 2026 Feb 19:S0896-6273(25)00984-

Insert

Sparcl1 (Sparcl1 Mouse)

Use

AAV

Tags

6xHis and Myc

Expression

Mammalian

Mutation

C-terminal fragment

Available Since

Jan. 16, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-GfaABC1D-mHevin-Myc-His

Plasmid

#249178

Purpose

AAV mediated overexpression of full length mouse Sparcl1

Depositor

Cagla Eroglu

Article

Ramirez et al Neuron. 2026 Feb 19:S0896-6273(25)00984-

Insert

Sparcl1 (Sparcl1 Mouse)

Use

AAV

Tags

6xHis and Myc

Expression

Mammalian

Available Since

Jan. 15, 2026

Availability

Academic Institutions and Nonprofits only

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