Sequence Type

BLAST Database

BLAST Algorithm

Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

We narrowed to 21,453 results for: SPR

Showing: 1761 - 1780 of 21453 results

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pLentiCRISPR-v1-sgHK2_14

Plasmid

#239257

Purpose

lentiviral vector expressing Cas9 and an sgRNA targeting HK2

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

sgRNA_14 targeting HK2 (HK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR V2 sgTMEM173_2

Plasmid

#241457

Purpose

Delete TMEM173 (STING)

Depositor

Richard Possemato

Insert

sgTMEM173_2 (STING1 Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pCRISPRa-Theo-1

Plasmid

#240207

Purpose

Bacterial CRISPRa vector expressing dCas9, MCP-SoxS, and a theophylline-responsive MR-scRNA

Depositor

Wilfred Chen

Article

Stohr et al Nucleic Acids Res. 2025 Nov 13;53(21):gk

Inserts

dCas9
MCP-SoxS
Theophylline MR-scRNA variant 1

Use

CRISPR

Expression

Bacterial

Promoter

J23107, J23119, and Sp.pCas9

Available Since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pSpRYa-Theo-1

Plasmid

#240208

Purpose

Bacterial SpRYa vector expressing dSpRY, MCP-SoxS, and a theophylline-responsive MR-scRNA

Depositor

Wilfred Chen

Article

Stohr et al Nucleic Acids Res. 2025 Nov 13;53(21):gk

Inserts

dSpRY
MCP-SoxS
Theophylline MR-scRNA variant 1

Use

CRISPR

Expression

Bacterial

Promoter

J23107, J23119, and Sp.pCas9

Available Since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pCRISPRa-Trp

Plasmid

#240209

Purpose

Bacterial CRISPRa vector expressing dCas9, MCP-SoxS, and a tryptophan-responsive MR-scRNA

Depositor

Wilfred Chen

Article

Stohr et al Nucleic Acids Res. 2025 Nov 13;53(21):gk

Inserts

dCas9
MCP-SoxS
Tryptophan MR-scRNA

Use

CRISPR

Expression

Bacterial

Promoter

J23107, J23119, and Sp.pCas9

Available Since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR V2 sgPOLD

Plasmid

#241444

Purpose

Delete POLD1

Depositor

Richard Possemato

Insert

sgPOLD (POLE Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Nov. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR V2 sgCGAS_2

Plasmid

#241455

Purpose

Delete CGAS

Depositor

Richard Possemato

Insert

sgCGAS_2 (CGAS Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Nov. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 SQLE_sg2

Plasmid

#244872

Purpose

Knockout of human SQLE

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

SQLE sgRNA (SQLE Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 UROS_sg1

Plasmid

#244873

Purpose

Knockout of human UROS

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

UROS sgRNA (UROS Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 SQLE_sg1

Plasmid

#244871

Purpose

Knockout of human SQLE

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

SQLE sgRNA (SQLE Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 UROS_sg2

Plasmid

#244874

Purpose

Knockout of human UROS

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

UROS sgRNA (UROS Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 PAPOLA_sg2

Plasmid

#244862

Purpose

Knockout of human PAPOLA

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

PAPOLA sgRNA (PAPOLA Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 ALAD_sg2

Plasmid

#244856

Purpose

Knockout of human ALAD

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

ALAD sgRNA (ALAD Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 ALAD_sg1

Plasmid

#244855

Purpose

Knockout of human ALAD

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

ALAD sgRNA (ALAD Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 HMBS_sg2

Plasmid

#244860

Purpose

Knockout of human HMBS

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

HMBS sgRNA (HMBS Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 PAPOLA_sg1

Plasmid

#244861

Purpose

Knockout of human PAPOLA

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

PAPOLA sgRNA (PAPOLA Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 HMBS_sg1

Plasmid

#244859

Purpose

Knockout of human HMBS

Depositor

Alexis Jourdain

Article

Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

Insert

HMBS sgRNA (HMBS Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pHS24_10xHis_MBP_TEV_SpRY-Cas9

Plasmid

#244827

Purpose

Bacterial expression of SpRY Cas9 for protein purification

Depositor

Jennifer Doudna

Article

Shi et al Mol Cell. 2025 May 1;85(9):1730-1742.e9.

Insert

SpRY Cas9

Use

CRISPR

Tags

10xHis-MBP

Expression

Bacterial

Mutation

A61R/L1111R/D1135L/S1136W/G1218K/E1219Q/N1317R/A1…

Promoter

T7

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pHS73_10xHis_MBP_TEV_SpRY-Cas9_2xNLS

Plasmid

#244835

Purpose

Bacterial expression of SpRY Cas9 with 2xSV40 nuclear localization sequence for protein purification

Depositor

Jennifer Doudna

Article

Shi et al Mol Cell. 2025 May 1;85(9):1730-1742.e9.

Insert

SpRY Cas9

Use

CRISPR

Tags

10xHis-MBP and 2xSV40 NLS

Expression

Bacterial

Mutation

A61R/L1111R/D1135L/S1136W/G1218K/E1219Q/N1317R/A1…

Promoter

T7

Available Since

Sept. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR-v1-sgNADK2

Plasmid

#233897

Purpose

lentiviral vector expressing Cas9 and an sgRNA targeting NADK2

Depositor

Jason Cantor

Article

Flickinger et al Nat Metab. 2025 May 2. doi: 10.1038/s422

Insert

sgRNA targeting NADK2 (NADK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge

Showing: 1761 - 1780 of 21453 results

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