We narrowed to 18,311 results for: MUT

1. pWZL-hygro-FAKY925F

   Plasmid

   #216547

   Purpose

   This retroviral plasmid expresses a mutated cDNA (dominant negative: Y925F ) of human PTK2

   Depositor

   Georgia Konstantinidou

   Article

   Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

   Insert

   PTK2 (Y925F) (PTK2 Human)
   

   Use

   Retroviral

   Tags

   No

   Expression

   Mammalian

   Mutation

   FAK dominant negative mutation Y925F

   Available Since

   Sept. 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pKIF1C_P176L-GFP

   Plasmid

   #185980

   Purpose

   Mammalian expression of human KIF1C with P176L mutation and GFP tag.

   Depositor

   Anne Straube

   Article

   Siddiqui et al Curr Biol. 2022 Sep 12;32(17):3862-3870.

   Insert

   KIF1C (KIF1C Human)
   

   Tags

   eGFP

   Expression

   Mammalian

   Mutation

   P176L - mutation causing HSP (SPG58)

   Promoter

   CMV

   Available Since

   July 6, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pTSlb-Q758C

   Plasmid

   #60729

   Purpose

   Expresses both fragments of T7 RNAP split at position 179. The N-terminal fragment is driven by PLac while the C-terminal fragment is driven by PBAD. C-terminal fragment has the point mutations Q758C

   Depositor

   Matthew Bennett

   Article

   Shis et al Proc Natl Acad Sci U S A. 2013 Mar 26;11

   Inserts

   Residues 1-179 of split T7 RNAP
   Residues 180-880 of split T7 RNAP
   

   Use

   Synthetic Biology

   Expression

   Bacterial

   Mutation

   Residues 1-180 of split T7 RNAP and Residues 180-…

   Available Since

   Nov. 4, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCEP4-CH115gp160-QES.c14-754*

   Plasmid

   #123282

   Purpose

   Mammalian expression plasmid for Env from the CH115 HIV-1 isolate; C-terminal truncation; QES mutant for enhanced presentation of quaternary epitopes

   Depositor

   Erik Procko

   Article

   Heredia et al J Virol. 2019 Mar 20. pii: JVI.00219-19.

   Insert

   HIV-1 (CH115) Env
   

   Tags

   CD5 leader peptide

   Expression

   Mammalian

   Mutation

   Codon-optimized synthetic gene; Premature stop co…

   Promoter

   CMV

   Available Since

   March 28, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pET22b-ecDHFR-N23PP/L28F/G51PEKN

   Plasmid

   #118585

   Purpose

   Bacterial expression of E.coli DHFR N23PP, L28F, and G51PEKN mutant

   Depositor

   Stephen Benkovic

   Article

   Liu et al Proc Natl Acad Sci U S A. 2013 Jun 18;11

   Insert

   DHFR
   

   Expression

   Bacterial

   Mutation

   N23 mutated to P23, L28 mutated to F28, G51 mutat…

   Promoter

   T7

   Available Since

   Nov. 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pTSara-R756K

   Plasmid

   #60727

   Purpose

   Expresses both fragments of T7 RNAP split at position 179. Both fragments are driven by PBAD. The C-terminal fragment has the point mutation R756K. Contains a constitutive araC ORF

   Depositor

   Matthew Bennett

   Article

   Shis et al Proc Natl Acad Sci U S A. 2013 Mar 26;11

   Inserts

   Residues 1-179 of split T7 RNAP
   Residues 180-880 of split T7 RNAP
   

   Use

   Synthetic Biology

   Expression

   Bacterial

   Mutation

   Residues 1-180 of split T7 RNAP and Residues 180-…

   Available Since

   Oct. 2, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCDF1-ADAM29 (wt)

   Plasmid

   #31143

   Depositor

   Yardena Samuels

   Article

   Wei et al Hum Mutat. 2011 Jun;32(6):E2148-75. doi:

   Insert

   ADAM29 (ADAM29 Human)
   

   Use

   Lentiviral

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   WT

   Available Since

   July 22, 2011

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCDF1-PTPRD-P459L

   Plasmid

   #25644

   Depositor

   Todd Waldman

   Article

   Solomon et al Cancer Res. 2008 Dec 15. 68(24):10300-6.

   Insert

   Protein tyrosine phosphatase receptor-type delta (PTPRD Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   tumor-derived mutation created by site-directed m…

   Available Since

   July 14, 2010

   Availability

   Academic Institutions and Nonprofits only

9. pCDF1-PTPRD-D1248N

   Plasmid

   #25646

   Depositor

   Todd Waldman

   Article

   Solomon et al Cancer Res. 2008 Dec 15. 68(24):10300-6.

   Insert

   Protein tyrosine phosphatase receptor-type delta (PTPRD Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   tumor-derived mutation created by site-directed m…

   Available Since

   Nov. 8, 2010

   Availability

   Academic Institutions and Nonprofits only

10. pTSlb-R756K

    Plasmid

    #60731

    Purpose

    Expresses both fragments of T7 RNAP split at position 179. The N-terminal fragment is driven by PLac while the C-terminal fragment is driven by PBAD. C-terminal fragment has the point mutations R756S

    Depositor

    Matthew Bennett

    Article

    Shis et al Proc Natl Acad Sci U S A. 2013 Mar 26;11

    Inserts

    Residues 1-179 of split T7 RNAP
    Residues 180-880 of split T7 RNAP
    

    Use

    Synthetic Biology

    Expression

    Bacterial

    Mutation

    Residues 1-180 of split T7 RNAP and Residues 180-…

    Available Since

    Nov. 4, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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11. pTSara-N748D

    Plasmid

    #60726

    Purpose

    Expresses both fragments of T7 RNAP split at position 179. Both fragments are driven by PBAD. The C-terminal fragment has the point mutation N748D. Contains a constitutive araC ORF

    Depositor

    Matthew Bennett

    Article

    Shis et al Proc Natl Acad Sci U S A. 2013 Mar 26;11

    Inserts

    Residues 1-179 of split T7 RNAP
    Residues 180-880 of split T7 RNAP
    

    Use

    Synthetic Biology

    Expression

    Bacterial

    Mutation

    Residues 1-180 of split T7 RNAP and Residues 180-…

    Available Since

    Oct. 2, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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12. pcDNA3.1-ADAM7 (H243Y)

    Plasmid

    #31138

    Depositor

    Yardena Samuels

    Article

    Wei et al Hum Mutat. 2011 Jun;32(6):E2148-75. doi:

    Insert

    ADAM7 (ADAM7 Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Histidine 243 changed to Tyrosine

    Available Since

    Sept. 1, 2011

    Availability

    Academic Institutions and Nonprofits only

13. pcDNA3.1-IARS2-H112A/P115A

    Plasmid

    #232338

    Purpose

    Expresses human IARS2 with putative isoleucine binding deficiency mutations (H112A and P115A) in mammalian cells, also carrying synonymous mutations described in Addgene #232340

    Depositor

    Quanfu Ma

    Insert

    IARS2 (IARS2 Human)
    

    Expression

    Mammalian

    Mutation

    Putative isoleucine binding deficiency mutation H…

    Promoter

    CMV

    Available Since

    June 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA3.1-IARS2-K664A/K667A

    Plasmid

    #232339

    Purpose

    Expresses human IARS2 with putative tRNA binding deficiency mutations (K664A and K667A) in mammalian cells, also carrying synonymous mutations described in Addgene #232340

    Depositor

    Quanfu Ma

    Insert

    IARS2 (IARS2 Human)
    

    Expression

    Mammalian

    Mutation

    Putative tRNA binding deficiency mutation K664A A…

    Promoter

    CMV

    Available Since

    June 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pWZL-hygro-FAKS722A

    Plasmid

    #216545

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: S722A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (S722A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation S722A

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pWZL-hygro-FAKY861F

    Plasmid

    #216546

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: Y861F) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (Y861F) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation Y861F

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pWZL-hygro-FAKY397F

    Plasmid

    #216677

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: Y397F) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (Y397F) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation Y397F

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pWZL-hygro-FAKS732A

    Plasmid

    #216541

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: S732A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (S732A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation S732A

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pWZL-hygro-FAKS910A

    Plasmid

    #216542

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: S910A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (S910A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation S910A

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pAc5.1B-lambdaN-HA-DmMe31B-Q281AH284A_E

    Plasmid

    #146204

    Purpose

    Insect Expression of DmMe31B-Q281AH284A

    Depositor

    Elisa Izaurralde

    Article

    Tritschler et al Mol Cell. 2009 Mar 13. 33(5):661-8.

    Insert

    DmMe31B-Q281AH284A (me31B Fly)
    

    Expression

    Insect

    Mutation

    one silent mutation A1101G and two non silent mut…

    Available Since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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