We narrowed to 285 results for: SPR

#130630

Knockout library targeting 16,977 genes. Each gene is targeted by an AsCpf1(AsCas12a)-based array containing 3-4 guides concatenated in one vector.

Giulio Draetta

Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

Sept. 9, 2019

Academic Institutions and Nonprofits only

#174163

Cytosine base editors for genome-scale knockout screens in human cells. Targets gene start codons, splice sites, or introduces premature termination codons.

Wensheng Wei

Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

Aug. 31, 2021

Academic Institutions and Nonprofits only

#171172

Induces knockouts of paralogous gene pairs. Plasmids express a pair of guide RNAs targeting either individual genes or a pair of paralogs.

Alice Berger

Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

Sept. 28, 2021

Academic Institutions and Nonprofits only

#216134

Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

Stefan Kubicek

Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

April 19, 2024

Academic Institutions and Nonprofits only

#221409

gRNA library to test the impact of transporters on biological processes

RESOLUTE Consortium, Giulio Superti-Furga

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Sept. 13, 2024

Academic Institutions and Nonprofits only

#190744

Targets proximal poly(A) signal sequences in genes identified to be differentially polyadenylated in the mouse B16-F10 melanoma system.

Robert Bradley

Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

Feb. 2, 2024

Academic Institutions and Nonprofits only

#169942

Knockout library targeting ubiquitin ligases, deubiquitinases, and control genes.

Benjamin Ebert

Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

Sept. 9, 2021

Academic Institutions and Nonprofits only

#226117

Contains 748 traditional and newly predicted epigenetic regulators using epigenetic network analyses that integrated gene codependency (DepMap) and protein-protein interaction data (BioPlex).

Rui Lu

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Oct. 29, 2024

Academic Institutions and Nonprofits only

#132561

Activation library targeting human SLC proteins.

Giulio Superti-Furga

Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

May 18, 2020

Academic Institutions and Nonprofits only

#216133

Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

Stefan Kubicek

Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

April 19, 2024

Academic Institutions and Nonprofits only

#157973

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#157972

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#157971

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#221410

gRNA library to test the impact of transporters on biological processes (subset: ABC transporters and controls)

RESOLUTE Consortium, Giulio Superti-Furga

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Sept. 13, 2024

Academic Institutions and Nonprofits only

#155200

Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

Benjamin Blencowe, Jason Moffat

Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

Sept. 2, 2020

Academic Institutions and Nonprofits only

#155199

Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

Benjamin Blencowe, Jason Moffat

Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

Sept. 2, 2020

Academic Institutions and Nonprofits only

#168776

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#168777

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#209734

CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

Thomas Gonatopoulos-Pournatzis

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

June 20, 2024

Academic Institutions and Nonprofits only

#209735

CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

Thomas Gonatopoulos-Pournatzis

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

June 20, 2024

Academic Institutions and Nonprofits only