We narrowed to 90 results for: cha;

1. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75316

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

3. Mouse sgRNA library Brie in lentiGuide-Puro

   Pooled Library

   #73633

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

4. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

   Pooled Library

   #75314

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

5. SPLINTR mCHERRY v1

   Pooled Library

   #179775

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

6. SPLINTR BFP v1

   Pooled Library

   #179776

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

7. SPLINTR GFP v1

   Pooled Library

   #179774

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

8. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75312

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

9. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

   Pooled Library

   #75315

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

    Pooled Library

    #75313

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

11. MYC-CRISPR

    Pooled Library

    #173195

    Purpose

    This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

    Depositor

    Agnieszka Dzikiewicz-Krawczyk

    Article

    Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 11, 2021

    Availability

    Academic Institutions and Nonprofits only

12. pSADB19-dTomato Barcode Library

    Pooled Library

    #227671

    Purpose

    RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of SADB19 strain G-deleted rabies virus.

    Depositor

    Cathryn Cadwell, Tomasz Nowakowski

    Article

    Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

    Expression

    Mammalian

    Species

    Synthetic

    Available since

    Feb. 12, 2025

    Availability

    Academic Institutions and Nonprofits only

13. CHyMErA LbCas12a Nuclease Optimization hgRNA Library

    Pooled Library

    #209734

    Purpose

    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

14. CHyMErA AsCas12a Nuclease Optimization hgRNA Library

    Pooled Library

    #209735

    Purpose

    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

15. Human Base Editing Sensor Library

    Pooled Library

    #179218

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

16. Mouse Base Editing Sensor Library

    Pooled Library

    #179217

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

17. pCVSN2c-MCP-oScarlet-KASH-6xMS2 Barcode Library

    Pooled Library

    #227672

    Purpose

    RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

    Depositor

    Cathryn Cadwell, Tomasz Nowakowski

    Article

    Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

    Expression

    Mammalian

    Species

    Synthetic

    Available since

    Feb. 12, 2025

    Availability

    Academic Institutions and Nonprofits only

18. CHyMErA Large-Scale Exon Deletion hgRNA Library

    Pooled Library

    #209736

    Purpose

    CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

19. HR700_TP53Exon5mut

    Pooled Library

    #229137

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

20. HR700_TP53Exon6mut

    Pooled Library

    #229138

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits