We narrowed to 238 results for: Gene

1. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

   Pooled Library

   #1000000113

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of mouse genes

   Depositor

   John Doench, David Root

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

2. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

   Pooled Library

   #1000000111

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   John Doench, David Root

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

3. RLC11

   Pooled Library

   #163955

   Purpose

   RLC11 pooled library

   Depositor

   Jeremy Rock

   Article

   Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

   Expression

   Bacterial

   Use

   CRISPR

   Available since

   Oct. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

4. Mouse Metabolism Library

   Pooled Library

   #163966

   Purpose

   Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

   Depositor

   Alec Kimmelman

   Article

   Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Use

   CRISPR and Lentiviral

   Available since

   July 1, 2021

   Availability

   Academic Institutions and Nonprofits only

5. RLC12

   Pooled Library

   #163954

   Purpose

   RLC12 pooled library

   Depositor

   Jeremy Rock

   Article

   Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

   Expression

   Bacterial

   Use

   CRISPR

   Available since

   Oct. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

6. pSMAL-CellTag-multi-v1 barcode library

   Pooled Library

   #206045

   Purpose

   The CellTag multi library of barcodes can be used to clonally label cells with DNA barcodes. These barcodes can be profiled directly with single-cell RNA and ATAC sequencing, to allow clonal tracking

   Depositor

   Samantha Morris

   Article

   Jindal et al Nat Biotechnol. 2023 Sep 25. doi: 10.103

   Use

   Lentiviral

   Available since

   Nov. 2, 2023

   Availability

   Academic Institutions and Nonprofits only

7. Oxford Drosophila melanogaster Genome-wide CRISPR Library

   Pooled Library

   #64750

   Purpose

   A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).

   Depositor

   Ji-Long Liu

   Article

   Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

   Expression

   Insect

   Species

   Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

   Use

   CRISPR

   Available since

   March 7, 2016

   Availability

   Academic Institutions and Nonprofits only

8. The Human Druggable CRISPR library

   Pooled Library

   #200013

   Purpose

   The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

   Depositor

   Lianxin Liu

   Article

   Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 9, 2023

   Availability

   Academic Institutions and Nonprofits only

9. Mouse lipid metabolism knockout library

   Pooled Library

   #206248

   Purpose

   The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

10. Pan-Druggable Cancer Library

    Pooled Library

    #182133

    Purpose

    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

    Depositor

    Prashant Mali

    Article

    Hu et al Biomaterials. 2022 Jan;280:121276. doi:

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 26, 2022

    Availability

    Academic Institutions and Nonprofits only