1,001 results

1. pAAV-hSyn-DIO-mCherry (AAV9)

   Viral Prep

   #50459-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hSyn-DIO-mCherry (#50459). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-mCherry plasmid DNA. hSyn-driven, Cre-dependent mCherry-expression control. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   Syn

   Tags

   mCherry (Cre-dependent)

   Available since

   April 25, 2019

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-hSyn-hChR2(H134R)-EYFP (AAV5)

   Viral Prep

   #26973-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-hSyn-hChR2(H134R)-EYFP (#26973). In addition to the viral particles, you will also receive purified pAAV-hSyn-hChR2(H134R)-EYFP plasmid DNA. hSyn-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   Syn

   Tags

   EYFP

   Available since

   March 7, 2018

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-Ef1a-mCherry (AAV9)

   Viral Prep

   #114470-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-Ef1a-mCherry (#114470). In addition to the viral particles, you will also receive purified pAAV-Ef1a-mCherry plasmid DNA. EF1a-driven mCherry expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   EF1a

   Tags

   mCherry

   Available since

   Jan. 6, 2022

   Availability

   Academic Institutions and Nonprofits only

4. pENN.AAV.CamKII 0.4.Cre.SV40 (AAV Retrograde)

   Viral Prep

   #105558-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pENN.AAV.CamKII 0.4.Cre.SV40 (#105558). In addition to the viral particles, you will also receive purified pENN.AAV.CamKII 0.4.Cre.SV40 plasmid DNA. CamKII-driven Cre expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   CaMKII

   Tags

   None

   Available since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

5. pENN.AAV.hSyn.Cre.WPRE.hGH (AAV Retrograde)

   Viral Prep

   #105553-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pENN.AAV.hSyn.Cre.WPRE.hGH (#105553). In addition to the viral particles, you will also receive purified pENN.AAV.hSyn.Cre.WPRE.hGH plasmid DNA. hSyn-driven Cre expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   Syn

   Tags

   None

   Available since

   Nov. 30, 2018

   Availability

   Academic Institutions and Nonprofits only

6. lentiCas9-Blast (Lentiviral Prep)

   Viral Prep

   #52962-LV

   Purpose

   Ready-to-use Lentiviral Prep particles produced from lentiCas9-Blast (#52962). In addition to the viral particles, you will also receive purified lentiCas9-Blast plasmid DNA. Lentiviral particles carrying Cas9 and blasticidin resistance. This virus is used to make stable cell lines expressing Cas9.

   Depositor

   Feng Zhang

   Article

   Sanjana et al Nat Methods. 2014 Aug;11(8):783-4. doi:

   Promoter

   EFS-NS

   Tags

   None

   Available since

   July 14, 2016

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-hSyn-DIO-hM3D(Gq)-mCherry (AAV2)

   Viral Prep

   #44361-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV-hSyn-DIO-hM3D(Gq)-mCherry (#44361). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM3D(Gq)-mCherry plasmid DNA. Syn-driven, Cre-dependent, hM3D(Gq) receptor with an mCherry reporter for CNO-induced neuronal activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Article

   Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d

   Promoter

   Syn

   Tags

   mCherry (Cre-dependent)

   Available since

   Nov. 29, 2016

   Availability

   Academic Institutions and Nonprofits only

8. Human sgRNA library Brunello in lentiGuide-Puro (Lentiviral Prep)

   Viral Prep

   #73178-LV

   Purpose

   Ready-to-use Lentiviral Prep particles produced from Human sgRNA library Brunello in lentiGuide-Puro (#73178). In addition to the viral particles, you will also receive purified Human sgRNA library Brunello in lentiGuide-Puro plasmid DNA. Ready-to-use lentiviral pooled library for CRISPR screening in human cells. Use on cells that are stably expressing Cas9 to make edits across 19,114 genes in the human genome.

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Promoter

   Tags

   None

   Available since

   Aug. 16, 2016

   Availability

   Academic Institutions and Nonprofits only

9. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV Retrograde)

   Viral Prep

   #87306-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Li Zhang

   Article

   Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

   Promoter

   EF1a

   Tags

   None

   Available since

   July 22, 2020

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-hSyn-DIO-hM4D(Gi)-mCherry (AAV2)

    Viral Prep

    #44362-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-hSyn-DIO-hM4D(Gi)-mCherry (#44362). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM4D(Gi)-mCherry plasmid DNA. hSyn-driven, Cre-dependent, hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Article

    Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d

    Promoter

    Syn

    Tags

    mCherry (Cre-dependent)

    Available since

    Nov. 29, 2016

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-CaMKIIa-hChR2(H134R)-EYFP (AAV9)

    Viral Prep

    #26969-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(H134R)-EYFP (#26969). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(H134R)-EYFP plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Lee et al Nature. 2010 Jun 10. 465(7299):788-92.

    Promoter

    CaMKII

    Tags

    EYFP

    Available since

    March 7, 2018

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-CaMKIIa-eNpHR 3.0-EYFP (AAV1)

    Viral Prep

    #26971-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CaMKIIa-eNpHR 3.0-EYFP (#26971). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-eNpHR 3.0-EYFP plasmid DNA. CaMKIIa-driven eNpHR 3.0-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    CaMKII

    Tags

    EYFP

    Available since

    Feb. 14, 2018

    Availability

    Academic Institutions and Nonprofits only

13. pGP-AAV-syn-jGCaMP8m-WPRE (AAV1)

    Viral Prep

    #162375-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-jGCaMP8m-WPRE (#162375). In addition to the viral particles, you will also receive purified pGP-AAV-syn-jGCaMP8m-WPRE plasmid DNA. Syn-driven expression of calcium sensor GCaMP8m (faster, more sensitive). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Zhang et al Janelia Research Campus, Online Resource

    Promoter

    Syn

    Tags

    None

    Available since

    May 18, 2021

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-hSyn-hM4D(Gi)-mCherry (AAV9)

    Viral Prep

    #50475-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSyn-hM4D(Gi)-mCherry (#50475). In addition to the viral particles, you will also receive purified pAAV-hSyn-hM4D(Gi)-mCherry plasmid DNA. hSyn-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    mCherry

    Available since

    Jan. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-Syn-ChrimsonR-tdT (AAV5)

    Viral Prep

    #59171-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-Syn-ChrimsonR-tdT (#59171). In addition to the viral particles, you will also receive purified pAAV-Syn-ChrimsonR-tdT plasmid DNA. Syn-driven ChrimsonR-tdTomato expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

    Promoter

    Syn

    Tags

    tdTomato

    Available since

    Feb. 7, 2018

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-hSyn-mScarlet (AAV1)

    Viral Prep

    #131001-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hSyn-mScarlet (#131001). In addition to the viral particles, you will also receive purified pAAV-hSyn-mScarlet plasmid DNA. Synapsin-driven mScarlet control vector. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Marshel et al Science. 2019 Aug 9;365(6453). pii: scie

    Promoter

    Syn

    Tags

    mScarlet

    Available since

    Nov. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-Ef1a-DIO eNpHR 3.0-EYFP (AAV1)

    Viral Prep

    #26966-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-Ef1a-DIO eNpHR 3.0-EYFP (#26966). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO eNpHR 3.0-EYFP plasmid DNA. EF1a-driven, cre-dependent eNpHR 3.0-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Gradinaru et al Cell. 2010 Apr 2. 141(1):154-65.

    Promoter

    EF1a

    Tags

    EYFP (Cre-dependent)

    Available since

    Feb. 14, 2018

    Availability

    Academic Institutions and Nonprofits only

18. pENN.AAV.CMVs.Pl.Cre.rBG (AAV9)

    Viral Prep

    #105537-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pENN.AAV.CMVs.Pl.Cre.rBG (#105537). In addition to the viral particles, you will also receive purified pENN.AAV.CMVs.Pl.Cre.rBG plasmid DNA. CMV-driven Cre. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CMV

    Tags

    None

    Available since

    June 29, 2018

    Availability

    Academic Institutions and Nonprofits only

19. pGP-AAV-syn-iGABASnFR2-WPRE (AAV1)

    Viral Prep

    #218874-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-iGABASnFR2-WPRE (#218874). In addition to the viral particles, you will also receive purified pGP-AAV-syn-iGABASnFR2-WPRE plasmid DNA. Syn-driven expression of the improved GABA sensor iGABASnFR2 (positive change in fluorescence). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Kolb et al bioRxiv 2025.03.25.644953

    Promoter

    Syn

    Tags

    None

    Available since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-hSyn-mCherry (AAV8)

    Viral Prep

    #114472-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-hSyn-mCherry (#114472). In addition to the viral particles, you will also receive purified pAAV-hSyn-mCherry plasmid DNA. Synapsin-driven mCherry control vector. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    Syn

    Tags

    mCherry

    Available since

    March 26, 2019

    Availability

    Academic Institutions and Nonprofits only