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  1. Neurodegeneration Plasmid Collection

    Type
    Collection
    ...92247 pJOP-HTT-HR30Q HTT copGFP E1Fa Huntington's Mahmoud Pouladi 92248 pJOP-HTT-HR45Q HTT copGFP E1Fa...92249 pJOP-HTT-HR65Q HTT copGFP E1Fa Huntington's Mahmoud Pouladi 92250 pJOP-HTT-HR81Q HTT copGFP E1Fa...His6-Ssp-Httex1-7Q HTT His T7 Huntington's Hilal Lashuel 84348 pTWIN1-His6-Ssp-Httex1-15Q HTT His T7 Huntington's...His6-Ssp-Httex1-23Q HTT His T7 Huntington's Hilal Lashuel 84350 pTWIN1-His6-Ssp-Httex1-29Q HTT His T7 Huntington's...His6-Ssp-Httex1-37Q HTT His T7 Huntington's Hilal Lashuel 84352 pTWIN1-His6-Ssp-Httex1-43Q HTT His T7 Huntington's...Garcia 157860 61427-sgHtt_6 HTT U6 Huntington's Xinyu Zhao 157861 61427-sgHtt_10 HTT U6 Huntington's Xinyu...-U6-sgHTT1-7sk-sgCas9 HTT U6, 7sk Huntington's Nicole Deglon 190901 pAAVss-U6-sgHTT51-7sk-Cas9 HTT U6,...

  2. Neurodegeneration Research Collection

    Type
    Collection
    ...series within the huntingtin (HTT) gene. An individual with the mutated HTT gene will have huntingtin proteins...neurodegenerative disorders. Find plasmids expressing HTT, C9ORF72, LRRK2, Synuclein, and more. New and Noteworthy...

  3. Structural Genomics Consortium Plasmids

    Type
    Collection
    ..., AmpR Related Resources SGC: http://www.thesgc.org/ SGC Toronto: https://www.thesgc.org/scientists/groups...groups/toronto SGC Oxford: http://www.sgc.ox.ac.uk/ Protein Database (PDB): http://www.pdb.org Request Plasmids...

  4. Zhang Lab's CRISPR Frequently Asked Questions

    Type
    Collection
    ...specificity. A good reference is this Cell paper: http://www.cell.com/abstract/S0092-8674(13)01015-5 As...plate. A good example/reference is this Cell paper: http://www.cell.com/abstract/S0092-8674(13)01016-7 In...

  5. Gibson Assembly Protocol

    Type
    Protocol
    ...hundred kilobases. Nature Methods , 6(5), 343–345. https://doi.org/10.1038/nmeth.1318 (Link opens in a new...mitochondrial genome. Nature Methods , 7(11), 901–903. https://doi.org/10.1038/nmeth.1515 (Link opens in a new...Enhancement for Gibson Isothermal Assembly. bioRxiv . https://doi.org/10.1101/2020.06.14.150979 (Link opens ...

  8. Viral Vectors 101: Systemic Capsids

    Type
    Blog Post
    ...more information on reagents and protocols, visit https://clover.caltech.edu. Figure adapted from Challis... Review of Neuroscience. 2022 Jul 8;45:447-469. https://doi.org/10.1146/annurev-neuro-111020-100834 Challis...in rodents. Nature Protocols;14, 379–414 (2019). https://doi.org/10.1038/s41596-018-0097-3 More resources...Using AAV-PHP.S. eNeuro,9(3), ENEURO.0373-21.2022. https://doi.org/10.1523/ENEURO.0373-21.2022 Brown, D.,...Sequencing. Frontiers in immunology, 12, 730825. https://doi.org/10.3389/fimmu.2021.730825 Campos LJ, Arokiaraj...system. Current Research in Neurobiology, 4, 100086. https://doi.org/10.1016/j.crneur.2023.100086. Challis... Annual Review of Neuroscience, 45(1), 447–469. https://doi.org/10.1146/annurev-neuro-111020-100834 Chan...

  9. Typing CRISPR Systems

    Type
    Blog Post
    ... with CRISPR–Cas13. Nature, 550(7675), 280–284. https://doi.org/10.1038/nature24049 Altae-Tran, H., Kannan... deep terascale clustering. Science, 382(6673). https://doi.org/10.1126/science.adi1910 Chylinski, K.,...systems. Nucleic Acids Research, 42(10), 6091–6105. https://doi.org/10.1093/nar/gku241 Cong, L., Ran, F. A...CRISPR/CAS systems. Science, 339(6121), 819–823. https://doi.org/10.1126/science.1231143 Cox, D. B. T.,...with CRISPR-Cas13. Science, 358(6366), 1019–1027. https://doi.org/10.1126/science.aaq0180 Harrington, L....CRISPR-Cas14 enzymes. Science, 362(6416), 839–842. https://doi.org/10.1126/science.aav4294 Hu, C., Myers,...applications. Molecular Cell, 84(3), 463-475.e5. https://doi.org/10.1016/j.molcel.2023.12.034 Kolesnik,...

  10. Viral Vectors 101: AAV Variables That Matter

    Type
    Blog Post
    ... Gene Therapy: An Overview. Cells, 12(5), 1–41. https://doi.org/10.3390/cells12050785 Murlidharan, G.,...system. Frontiers in Molecular Neuroscience, 7. https://doi.org/10.3389/fnmol.2014.00076 References and...and 9 in the Mouse Brain. PLOS ONE, 8(9), e76310. https://doi.org/10.1371/journal.pone.0076310 Damdindorj...adeno-associated viral vectors. PLoS ONE, 9(8), 1–10. https://doi.org/10.1371/journal.pone.0106472 de Backer...Hypothalamus. Human Gene Therapy, 21(6), 673–682. https://doi.org/10.1089/hum.2009.169 Dudek, A. M., Pillay...Independent of AAV Receptor. Journal of Virology, 92(7). https://doi.org/10.1128/jvi.02213-17 Favre, D., Blouin...Virus. Journal of Virology, 76(22), 11605–11611. https://doi.org/10.1128/JVI.76.22.11605-11611.2002 Griffin...
Showing: 1 - 10 of 246 results