We narrowed to 24 results for: sam

Choosing a CRISPR activator? This article features four of the most popular CRISPR activators (dCas9-VP64, SAM, SunTag, and VPR) and some newer activators like dCas9-CBP and SPH.

New CRISPR pooled libraries, such as SAM, CRISPRa, and CRISPRi, offer new ways to do genome-wide functional screens.

Scientists are currently developing disease treatments using CRISPR. Learn about recent developments in the fight against HIV-1 with CRISPR.

A review of protein expression mechanisms for on, off, and tunable, control of protein expression.

We announce the winners of our 2021 Deck the Lab competition!

CRISPR Cas9 gRNA plasmids from the Zhang lab

The labs of John Doench and David Root have recently created CRISPR libraries to knock out, inactivate, or activate genes for genome-wide screens. These optimized libraries are effective for probing gene function while using fewer sgRNAs.

In this blog post, learn how Addgene tracks samples and how you could implement a similar system in your lab.

Dr. Michael Koeris is cofounder Biotech startup, Sample 6, and a member of the Addgene Board. Listen to his journey from grad student to entrepreneur.

Discover the best situations to use Cas9 activators in your experiments with tips from their creators.

Having trouble with viral vectors? Here are several tips to help prevent recombination in viral vectors or other plasmids with repeating elements.

Get a behind-the-scenes glimpse of the design behind Addgene's new homepage and mascot update.

Learn how dry ice shipment can affect pH and discover precautions you can take to protect your virus samples.

Learn all about a highly processive reverse transcriptase, a new nanobody toolkit, and CRISPR-based tools for monitoring protein-DNA interactions

Learn about the latest CRISPR plasmids deposited at Addgene, including a miniature CRISPR-Cas systems, SEND plasmids, and prime editing improvements

Did you know CRISPR can be used to target non-coding RNAs? In this blog post, we explain the pros and cons of different approaches.

With many different Cas9 variants out there, it can be hard to know which one to use in your particular CRISPR experiment. This post is here to help.

Explore Addgene's collection of luciferase plasmids for gene expression assays and bioluminescent reporters.

Learn how to plan a basic CRISPR experiment, including selecting the edit type, designing and cloning a gRNA, delivering Cas and the gRNA, and validating the edit.

Addgene's guide to using Chemogenetics plasmids in your lab for interrogation of neuronal activity.