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There are many ways to study Dopamine including in vivo microdialysis and genetically encoded biosensors. Read on to learn about two recently developed biosensors: dLight and GRABDA.

The Addgene viral team has found a way to increase AAV yields through media supplementation of sucrose, an endocytosis inhibitor.

Tips on how to choose compatible fluorescent proteins for multi-color imaging.

Western blots have many technical elements. We cover each element, and the different options available to choose from, in this post.

Laura Drepanos from the Broad Institute shares the strategies her team used to optimize the CRISPR knockout libraries Jacquere and Julianna.

Addgene has updated our useful CRISPR guide to include PRIME editing, new enzymes, and more!

Browse neurodegeneration plasmids for research related to Alzheimer's Disease, ALS, Frontotemporal Dementia, Huntington's Disease, Parkinson's Disease, and others.

A review of the CasPEDIA resource and its features.

Description of the components of the 4 most common viruses - AAV, adenovirus, lentivirus, and gamma-retrovirus.

Learn about SF-iGluSnFr, an updated glutamate biosensor from Loren Looger's lab.

We guide you through a series of questions and considerations to help you pick an antibody for any experiment, along with a handy flow chart.

Get the basics on monoclonal antibodies including how monoclonal antibodies are made and why use monoclonal antibodies for your experiment.

If you're looking for a STEAM internship, find tips for a successful application season in this blog post written by the founders of STEAMid.

If you’re using CRISPR to make a genome edit, how do you know if your experiment was successful? Try using fluorescent CRISPR reporters like SRIRACCHA and GEmCherry2.

Learn how dry ice shipment can affect pH and discover precautions you can take to protect your virus samples.

Learn about new tools in Addgene's collection!

Learn more about NanoBiT technology and explore examples of HiBiT-tagged fusion proteins in action.

Learn how repressible promoters work and how you can use them in your next experiment.

Three studies recently showed that CRISPR can be used to treat Duchenne muscular dystrophy in mice. Learn about the work and obstacles to application.

A deep dive into qPCR with a focus on analysis, chemistries, and bench tips.