Skip to main content

We narrowed to 943 results for: Arch

Showing: 241 - 260 of 943 results
  1. Addgene Welcomes John Doench to the Advisory Board

    Type
    Blog Post
    ...he helps researchers in a variety of fields develop RNAi screens to answer their own research questions...guide and promote Addgene in its mission to make research easier. Addgene is excited to announce that we...ended... it was actually something bordering on research, rather than 'here’s the protocol, get a result...later realizing that he wanted to continue doing research, Doench went on to apply to graduate school at...incredible place.” Doench has spent most of his research career working on miRNAs and RNAi. He first heard...specificity in the miRNA regulatory process. This early research is still relevant to his work at the Broad Institute...
  2. Finding and Joining Your Dream Lab

    Type
    Blog Post
    ...wondering “What is this PI looking for in a new researcher?,” “How do I convince the PI to choose me?” We...about awesome science. Important factors in the search for a lab Studies show that job satisfaction (especially...graduate student or postdoc. Although the chosen research field is important, the end goal during this time...tasks like a scientist. Of course, the specific research field should be interesting; however, this should...biotech, this is one case where the topic of your research can make your transition easier – choose a lab...Posts in this Blog Series: Advice for Choosing a Research Project 9 Tips to Achieve Success in Academia... search for a lab...
  3. Addgene’s Viral Service - Why Virus? Why Now?

    Type
    Blog Post
    ...mission is to Accelerate research and discovery by improving access to useful research materials and information...Can Use the Viral Service in Your Research Using Virus in Your Research - A Primer for Beginners Resources...lab from MIT and Alla Karpova’s lab from Janelia Research Campus have provided valuable insight into AAV...focus on assisting scientists and accelerating research and discovery, while also pushing us to challenge...Visit Our Viral Vector Pages Find Virus for Your Research ...
  4. Important Considerations When Using AAVs

    Type
    Blog Post
    ...selecting which particular AAVs to use for your research. Below I’ll provide some tips that will help you...think about how to get started with AAVs. Since my research is rooted in the CNS, my focus will be mostly ...tolerated, then axonal transport is fine and a researcher should aim to inject a larger amount of vector...kB [9]).     4. The Future What new types of research may be enabled by the use of AAVs? 1) Combined...potential problem in many experiments, a group of researchers has identified this feature of AAVs as a new ... to study neural control. Surprisingly, little research has compared and contrasted optogenetic and chemogenetic... the most appropriate vehicle for this type of research, as they are safe to use in vivo. 3) The use ...
  5. Reproducibility for Everyone: Lessons from an Open Science Collaboration

    Type
    Blog Post
    ...materials, Sonali Roy, a postdoctoral researcher at the Noble Research Institute, co-instructed the ASPB ...organized a panel to discuss reproducibility issues in research. But he realized that it wasn’t enough to discuss... that running interactive workshops to train researchers on tools and best practices could be an actionable... practices being adopted by a wider group of researchers. Generating material to empower others to practice... the materials in one place and better serve researchers at all levels of the scientific community. Lessons...interactive workshops that train and provide researchers with tools and best practices could be an actionable...
  6. Uncertainty about Labor Law Brings More Uncertainty to Postdoc Wages

    Type
    Blog Post
    ...Gary McDowell, executive director of Future of Research. On December 1st 2016, many postdocs working more...reversing these decisions entirely. At Future of Research, we had been collecting data and documenting the...blogpost and more recently in a paper published in F1000Research on November 2016. Due to the nature of the postdoc...was granted nationwide. Again, we at Future of Research believe that, while the mandate has been removed...what their institution is doing from Future of Research over social media, not from their institution)... currently the Executive Director of Future of Research. He is interested in advocating for and with junior... him on Twitter @BiophysicalFrog and Future of Research @FORsymp.   Additional Resources on the Addgene...
  7. Custom CRISPR Screens & the Green Listed Software

    Type
    Blog Post
    ...by guest blogger Fredrik Wermeling, leader of a research group at the Centrum for Molecular Medicine (CMM... different gRNAs. It has been suggested that researchers should use ~400X more cells than gRNAs in a screen...are addressing a well-defined, hypothesis driven research question. Examples of custom CRISPR screens Differentially...analyses like RNAseq are getting lower and lower, the research community is generating a massive amount of descriptive...such data. These targeted screens can allow a researcher to test which of the differentially expressed...embedded. These were kindly donated by six different research constellations: Doench/Root (2), Zhang (3), Wu...screen! Final note I am very grateful to the researchers letting us use their reference libraries thereby...
  8. Cancer and the Immune System: Deciphering the Relationship

    Type
    Blog Post
    ...longer than we’ve been studying it and, now, researchers are exploring ways to bolster and modulate our...protein blocking. Other molecular targets under research include TIM-3, LAG-3, STAT-3, EGFR, CD20 and CD73...to activate them are a few methodologies being researched. Apoptotic and necroptotic tumor cells have also...engineering have played a huge role. For instance, researchers are genetically altering tumor cells and immune... treatments enter the clinic, physicians and researchers are learning much about how treatment regimens... made more effective. Some important factors researchers are beginning to focus on include: Cell heterogeneity... important questions in this exciting field of research. One of the most important: How will cancers evolve...
  9. Viral Vectors 101: Virus Safety

    Type
    Blog Post
    ...than cell cultures do, and tired researchers are accident-prone researchers. Note that safety policies will...have become a regular part of basic biological research as well as clinical therapy. These biological ...in non-target cells, including yourself as the researcher.   Figure 1: Separation of retroviral ... delivered, that is a higher risk cargo for a researcher to come into contact with than GFP. Similarly...need to be done in a biosafety cabinet. Many researchers choose to wear eye protection when they are working...likely to want to cut a few corners. For many researchers, viruses might be the most dangerous things they...
  10. Experimenting in an Open Source lab: from CRISPR to Cats

    Type
    Blog Post
    ... involved in developing tools and solutions to research problems. This movement calls itself the Open ...and is part of a bigger movement in a variety of research sectors to provide open source technologies and...and spaces where interested parties can do research. This interest manifested itself in the creation of...collaboratively to solve, we want to focus our research on worm locomotion, but our worms are constantly...automated microscope  to keep our worms and our research goals in focus. Developing these skills relies...submit our new strains back to the CGC for other researchers to use. Although we haven’t yet made our final...University of Victoria. After a decade at Microsoft Research working on speech recognition, he returned to ...
  11. Quick Guide to Working with Drosophila Part 1: Getting Started with Flies

    Type
    Blog Post
    ...show you how Drosophila can be used to push your research in new and exciting directions. Drosophila are...the fourth and Y chromosomes are miniscule, so researchers generally do not manipulate them. Essentially...accessible resource out there to help keep your research moving. Below, you’ll find some great introductory... resources. As you dive deeper into Drosophila research, you’ll find more resources that may be more tailored...look up information about your fly gene using the search box in the upper right hand corner. They have video...Drosophila reagents are generously shared among the research community. They maintain many fly stocks that ...stocks are available at Bloomington, but you can search for various fly reagents on the Bloomington website...
  12. Synthetic Biology - Algal

    Type
    Collection
    ...biology plasmids for use in algae. Algal Plasmids Search the table by keyword or sort by the table headings...
  13. Synthetic Biology - Bacterial

    Type
    Collection
    ...plasmids for use in bacteria. Bacterial Plasmids Search the table by keyword or sort by the table headings...
  14. Synthetic Biology - Fungal

    Type
    Collection
    ...biology plasmids for use in fungus. Fungal Plasmids Search the table by keyword or sort by the table headings...
  15. Synthetic Biology - Mammalian

    Type
    Collection
    ...for use in mammalian systems. Mammalian Plasmids Search the table by keyword or sort by the table headings...
  16. Synthetic Biology - Plant

    Type
    Collection
    ...biology plasmids for use in plants. Plant Plasmids Search the table by keyword or sort by the table headings...
  17. Synthetic Biology - Worm

    Type
    Collection
    ...biology plasmids for use in C. elegans. Worm Plasmids Search the table by keyword or sort by the table headings...
  18. Synthetic Biology - Yeast

    Type
    Collection
    ...biology plasmids for use in yeast. Yeast Plasmids Search the table by keyword or sort by the table headings...
  19. Isolating Genomic Regions of Interest with the CRISPR System

    Type
    Blog Post
    ...While much of CRISPR research has focused on genome editing, numerous discoveries have been made using...But dCas9 does not cleave the DNA. Much of the research using dCas9 has focused on transcriptional activation...antibody targeting the 3xFLAG tag, allowed these researchers to isolate dCas9 with the bound genomic locus...flavors to this methodology. Using this technique, researchers have begun to make important discoveries in various... region, other forms of enChIP, and additional research conducted in the Hodaka Fujii Laboratory, please...enChIP) using CRISPR." Biochemical and biophysical research communications 439.1 (2013): 132-136. PubMed PMID...the analysis of bacterial genome functions." BMC research notes 11.1 (2018): 387. PubMed PMID: 29898790....
Showing: 241 - 260 of 943 results