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We narrowed to 600 results for: ARL

Showing: 281 - 300 of 600 results
  1. Hot Plasmids Spring 2024

    Type
    Blog Post
    ... Janelia, are now available! Building on their earlier Voltron indicators (a fusion of Ace2N and HaloTag...Neurodegeneration Research Collection. This page is regularly updated with useful materials for research into...
  2. Finding nucleic acids with SHERLOCK and DETECTR

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    Blog Post
    ...CRISPR Cas variant that can also cleave dsDNA similarly to Cas9 (Zetsche et al., 2015 ). Cas12a however...DETECTR. How does DETECTR work? DETECTR works similarly to SHERLOCK. Cas12a is targeted to a specific ...
  3. Career Insights: Technical Support Specialist

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    Blog Post
    ... your technical knowledge and judgement. For particularly tricky cases, team discussions can often lead...doing a lot of science communication, and is particularly excited to hear about novel developments in ...
  4. Fluorescent Proteins 101: Aptamer Fluorophores

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    Blog Post
    ...What is an aptamer? Nearly 30 years ago, two independent groups, led by Jack Szostak and Larry Gold, ... Assays that require recognition of ions or particularly small molecules that do not generate an immune...
  5. Using Video to Share Your Science: We Share Science

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    Blog Post
    ...article is an interactive chart where you can see the yearly interdisciplinarity index of research for single...and case study." Journal of Librarianship and Scholarly Communication 2.2 (2014): 2. Additional Resources...
  6. Changing Labor Laws Bring Increased Postdoc Wages

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    Blog Post
    ...major effect on scientists within academia, most particularly postdocs working in the U.S., whose current ...thing. Reliance on a cheap trainee workforce has clearly not been a sustainable approach to biomedical research...
  7. The Challenges of Cell Culture

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    Blog Post
    ... is still a problem today. It is now known that nearly 500 cell lines suffer from contamination with HeLa...out on low passage cells and this means you can regularly discard the cells you are working with because...
  8. Getting the Most from Your Lentiviral Transduction

    Type
    Blog Post
    ...American Type Culture Collection and freeze as many early passage vials as possible. One problem that often...can make this assumption incorrect. One of the earliest steps in lentiviral transduction is the interaction...
  9. Plasmids 101: The Promoter Region – Let's Go!

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    Blog Post
    ...between cell types or organisms, promoters must be similarly variable. Bacterial promoters only work in prokaryotic...related species from which they were derived. Similarly, the various eukaryotic cell types (mammalian,...
  10. Five Popular Model Organisms, Part 2

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    Blog Post
    ...conducted a large scale sequencing and concluded that nearly all disease-linked human genes have counterparts...the most popular model amphibians in science with early research providing insight into some of the most...
  11. Hot Plasmids: Summer 2024

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    Blog Post
    ...while requiring a lower concentration of sample — nearly ten times less protein. While the addition of LEAs...Methyltransferase (CHARM), with several advantages over the earlier system.  Rather than overexpressing an exogenous...
  12. Antibodies 101: Beyond Surface Labeling

    Type
    Blog Post
    ... glycosylation patterns. Surface labeling is particularly useful for classifying and sorting cells by ...Paul Heisig is a Research Associate in the lab of Arlene Sharpe at Harvard Medical School. His projects ...
  13. New Optogenetic Tools for Cytoskeleton and Membrane Control

    Type
    Blog Post
    ... under CC-BY 4.0 license.   Building off their earlier work on Rab11, the team used optogenetic clustering...constructs to the plasma membrane or lysosomes (the earlier article also provided CIB constructs for targeting...
  14. Tips for Getting a Faculty Position

    Type
    Blog Post
    ... interviews but no job offers, is a failure to clearly articulate one's talents and ideas. Some key points... matter how many times I say this, candidates regularly try to convince me that their search committee...
  15. Filming Science Videos in the Age of Social Distancing

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    Blog Post
    ...other videos. For starters, I hadn’t anticipated nearly every webcam recording only 1280x720 resolution... to labs that need them. The lab re-opened very early in the pandemic with some incredibly strict safety...
  16. SARS-CoV-2/COVID-19 Detection Methods Based on CRISPR/Cas

    Type
    Blog Post
    ...distancing. With countries like South Korea, one of the earlier epicenters of the outbreak ultimately flattening... is a one-pot, one-temperature reaction, and is nearly single-molecule sensitive. In the case of HIV-1...
Showing: 281 - 300 of 600 results