We narrowed to 562 results for: pac
-
TypeBlog Post...why hot dogs are sold in packages of 8 yet hot dog buns are sold in packages of 10…) If you missed the...
-
Hot Plasmids - February 2022
TypeBlog Post... of performing similarly to Cas9 screens in a compacted library. Overall, Cas12a’s ability to target multiple...significant off-target effects, yet small enough to be packaged in AAV. A dCasMini-mediated adenine base editor... -
Clear and Accessible Writing
TypeBlog Post...the use of alt text to describe images in online spaces. Alt text is used by screen readers to provide ...professional development workshop, “Make a Greater Impact Using Clear and Accessible Scientific Writing.”... -
CasPEDIA: A Functional Classification of Cas Enzymes
TypeBlog Post...a gRNA is useless without an adjacent PAM or protospacer-flanking sequence (PFS) in some cases. The resource...the protein would be helpful to know for viral packaging limitations. Maybe you want to read literature... -
Viral Vectors 101: Biosensors
TypeBlog Post...with some of our most popular biosensors already packaged and ready to deliver. Ready to give biosensors...AAV as your vehicle, we’ve got you covered with packaging plasmids! References and Resources References... -
GCE4All: Making Genetic Code Expansion Accessible
TypeBlog Post...tricky to find: each of the factors can negatively impact both translation and fidelity of translation, leading.... Or, to quote Ryan Mehl, PhD, GCE has “10x the impact of PCR. But it’s 100x more complicated.” And Ryan... -
Viral Vectors 101: Viral Applications
TypeBlog Post... these amazing tools in your experiments? Let’s unpack the myriad number of emerging viral applications...just one at a time. Many of these libraries are packaged and delivered with viral vectors instead of a ... -
How Addgene Creates Content
TypeBlog Post...over their favorite science topics. What better space to do that than in the Addgene blog? Fig...expertise of our antibody team to rely on. High-impact content like the antibody guide always gets an ... -
Antibodies 101: Monoclonal Antibodies
TypeBlog Post...of the antibody - the paratopes - may change and impact the specificity and avidity of the antibodies produced... chain or light chain genes within a hybridoma impacts the specificity, avidity, and number of different... -
A Novice's Perspective on Neuroscience - SfN2017
TypeBlog Post... about and develop technologies that will have impacts on many different facets of life. It also seems...neuroscience. AAV tools from Addgene are already having an impact on the field Not to toot our own horn too much,... -
Oh, The Places You Can Go: Careers in Science Communication - Writing for a Research Institute
TypeBlog Post...different directions is sometimes at odds with the space needed to be creative. “You need a lot of time to...readers with it.” She feels that storytelling is an impactful tool for science communicators. “The power of ... -
CRISPRainbow and Genome Visualization
TypeBlog Post...editing, but it retains its gRNA-directed targeting capacity. By using a gRNA to target fluorescently labeled...that they could evaluate the degree of chromatin compaction even for this small distance! To the authors’... -
Reproducibility for Everyone: Lessons from an Open Science Collaboration
TypeBlog Post...enough workshops by herself to make the biggest impact. When she spoke with Teytelman about an opportunity...Use your network well to seek out valuable and impactful opportunities - There are many brilliant minds... -
Summer SciComm: Preprints
TypeBlog Post...scientists know the results, your work won’t have any impact! There are lots of ways scientists communicate...efforts, inspire future research, and increase their impact. Open access and transparency Another major benefit... -
Antibodies 101: Affinity Reagents
TypeBlog Post...amazing affinity reagents we just didn't have the space to give proper credit to. Thankfully, as Addgene's..., or be able to access an epitope folded into a space that would size-exclude an antibody. In imaging ... -
Addgene: The First Twenty Years
TypeBlog Post...distributed milestone! We were thrilled to see the impact our repository was having on the scientific community...expanding our viral vectors service to include AAV Packaged on Request! “I love Addgene. I think resources... -
Hot Plasmids - March 2020 - base editors, GEVI, MoClo, and optogenetics
TypeBlog Post...therapy delivery mechanism, but their small packaging capacity of 4-5 kb limits the delivery of larger transgenes... -
Gendered Innovations: Why Does Sex of the Cell Matter?
TypeBlog Post...that there are sex differences in the therapeutic capacity of stem cells. Yet, very few researchers consider...Future of Research Learn How Notions of Scientific Impact Are Evoloving Check Out Extracurricular Activities... -
Addgene's Tips for Plasmid Quality Control
TypeBlog Post...the many freely-available DNA-editing software packages to assemble your expected full plasmid sequences...when designing a sequencing primer, you need some space between your primer binding site and the first feature... -
Engaging with science and society at pgEd
TypeBlog Post...But as the science moves forward at a blistering pace, it is becoming ever more urgent for scientists ...at pgEd, I take on a variety of projects in the space of science education, communication, and policy....