...currently two Gi DREADDs based on human muscarinic receptors, hM2Di and hM4Di, and a Gi DREADD based on...hM5Dq, however, hM3Dq is the most widely employed. Gi-DREADDs signal through the Gαi/o G-protein and inhibit...Controlling signaling with a specifically designed Gi-coupled receptor. Proc Natl Acad Sci USA. 95:352–... (2019). Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics...

...Cre-dependent DREADD Roth 44362 pAAV-hSyn-DIO-hM4D(Gi)-mCherry Syn Inhibitor, Cre-dependent DREADD Roth...

...-activated dimerization, using proteins GIGANTEA (GI) and the light oxygen voltage (LOV) domain of FKF1...engineered zinc finger proteins, using proteins GIGANTEA (GI) and the light oxygen voltage (LOV) domain of FKF1...