We narrowed to 537 results for: PAN

... a startup company. However, like many like-minded people, I quickly realize that a company requires more...during graduate school and turn it into a biotech company. Transitioning an idea from academia to a startup...not remove himself from the idea of starting a company around engineered bacteriophages. He decided to...Development & Operations. Starting a biotech company When and how does a startup become "successful...cornerstone of it all. Without a good nucleus, the company won’t go anywhere. The team should initially consist...conversation about its goals and vision for the company; this will help avoid future complications and ...that waste money and time. Most importantly, “the company does not become real until someone takes the risk...

... (Jason Rasgon) This lab is developing tools for pan-arthropod genetic manipulation. The ReMOT control...scientific sharing The EDGE Program is designed to expand the number of systems that can be studied by providing...

...Cancer Mutant Collection) or “pan-cancer” analyses across many cancer types (Pan Cancer Mutant Collection)...Cancer Discovery 2016. PubMed PMID: 27147599. The pan cancer mutant collection and the genetic pathway ...

...gain insight into protein structure and function (Pan et al., 2018). cDNA libraries, which consist of plasmids...Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman...517:583–588 . https://doi.org/10.1038/nature14136 Pan J, Meyers RM, Michel BC, Mashtalir N, Sizemore AE...

...Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman...rationally designed mutations. Researchers have expanded the CRISPR field beyond SpCas9, moving us closer...and translational technologies. Biotechnology companies are exploring therapeutic applications of CRISPR...

...Kv. C) Cultured rat hippocampal neuron expressing pan-membrane ASAP5. Solid blue circle marks the initiation... soma via the Kv2.1 targeting motif as well as a pan-membrane construct without the Kv motif. Altogether...and the soma. The initiation site identified in panel (C) is indicated; red line is exponential fit. Adapted...

...with Zebrabow Before the generation of Zebrabow (Pan et al., 2011), Brainbow was also used in zebrafish...Nature 450.7166 (2007): 56. PubMed PMID: 17972876. Pan, Y. Albert, et al. "Multicolor Brainbow imaging in...cutaneous melanoma induced by mutant BRaf arises from expansion and dedifferentiation of mature pigmented melanocytes...

...different isotypes. (A) Neocortex labeled with anti-pan-Nav (magenta), anti-CASPR (green), and anti-Kv2.1...Secondary antibody SCN1A sodium channels anti-pan-Nav R-mAb K58/35R (Mouse IgG2a) Goat anti-mouse...anti-AnkyrinG (green), and Hoechst nuclear stain (cyan). Panels C1-C3 show magnified detail of the box in C. Image...). Even better, show each channel in individual panels, then the multicolor overlay; this helps all viewers...

...E., Chen, Y., Whitehead, E. H., Guimaraes, C., Panning, B., Ploegh, H. L., Bassik, M. C., Qi, L. S., Kampmann...relative ease. Over the past decade, researchers have expanded the CRISPR toolbox to include many different types...target in your samples to ensure there are no discrepancies with the reference sequence you used for gRNA...

...resistance, Bhang says “the [drug] resistance story panned out quickly,” and was summarized in a recent Nature...

...Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman...

...for neuron-specific expression (hSyn promoter) and pan-mammalian cell expression (CAG promoter). An improved...

... for your experiment. If you’re looking for more pan-genome PAM flexibility, you’ll want to consider one...., et al.,Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science 361,1259-1262(2018). ... on the Addgene blog The PAM Requirement and Expanding Beyond Cas9 xCas9: Engineering a CRISPR Variant...

.... PubMed PMID: 18845710. Kim, Dal Hyung, et al. "Pan-neuronal calcium imaging with cellular resolution...

...alpha (aCaMKII; excitatory neurons) and Synapsin-1 (pan-neuronal) promoters (Figure 1b), and sgRNAs can be...

....2022.09.015 Ramani, B., Rose, I. V., Teyssier, N., Pan, A., Danner-Bocks, S., Sanghal, T., Yadanar, L., ...

...10.1074/jbc.TM118.000372 Yang, H., Ren, S., Yu, S., Pan, H., et al. Methods favoring homology-directed repair...

...Lovett, S. P., Parker, K., Radune, D., Hatada, A., Pan, C. Y., Rizzo, K., Bertumen, J. B., Morales, C., ...

...by infecting bacteria for additional rounds of panning and scFv characterization.    Figure 2: ...