We narrowed to 651 results for: PPL
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TypeBlog Post... to eliminate the use of antibiotics by their suppliers, and public health and medical organizations are...bacterial host range. To further potential clinical applications, Ando et al. recently engineered synthetic phages...
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Cpf1: A New Tool for CRISPR Genome Editing
TypeBlog Post...-target editing in a cell culture model. The application of Cpf1 to genome editing is exciting both in...in terms of basic science and translational applications. This discovery of this type V CRISPR system ... -
Interview: Hodaka Fujii on enChIP, New CRISPR Tools, and More
TypeBlog Post...describe this technology and some of its potential applications? Fujii: We generated a series of retroviral ...the peer-review system of journals and grant applications, for example. However, at the same time, it'... -
Your Lentiviral Plasmid FAQs Answered
TypeBlog Post...lentiviral plasmids created for a variety of applications including cDNA expression, shRNA-mediated knockdown...type or tissues; this is useful in gene therapy applications where a distinct subset of the cellular population... -
Rett Syndrome: A History of Research and Therapeutic Outlooks
TypeBlog Post...). Neurology 92 (15 Supplement) . http://n.neurology.org/content/92/15_Supplement/S51.002.abstract Sinnamon... -
Overcoming the AAV Size Limitation for CRISPR Delivery
TypeBlog Post...finding smaller Cas9 orthologs works for some applications, it doesn’t eliminate the need to deliver larger...https://doi.org/10.1126/science.aaq0180 Fine EJ, Appleton CM, White DE, Brown MT, Deshmukh H, Kemp ML, Bao... -
pCXLE toolkit: Efficient episomal plasmid-based method to reprogram peripheral blood cells to iPSCs
TypeBlog Post...possibilities for the clinical and therapeutic applications of iPSCs. The generation of human iPSCs (hiPSCs...., Recent technological updates and clinical applications of induced pluripotent stem cells. Korean J ... -
Transferable Skills Guide: Career Planning Resources
TypeBlog Post...connection you made at the job fair when you formally apply for the position. This post on Business Insider ...those relationships. Then when you are ready to apply for your dream job, you’ll be in the best possible... -
Plasmids 101: Plasmid Incompatibility
TypeBlog Post...way to bacterial cloning glory, scientists have applied these concepts to deal with the more sinister plasmids...pestis using plasmid incompatibility. Letters in Applied Microbiology 47:235–240 . https://doi.org/10.1111... -
Designing Your Chalk Talk for the Academic Job Interview
TypeBlog Post.... Given this large sum, one might expect that applicants would work for months to hone a chalk talk. Yet...of common questions, check out this eBook about applying for faculty positions. You need to practice with... -
Lab to Office Culture Shock
TypeBlog Post... scientist position at Addgene, the skeptical applicant asked if she would partake in “critical thinking...thinking” in the position to which she was applying. I probably did not respond to her question as well then... -
Hot Plasmids: Fall 2024
TypeBlog Post...performs well in many different antibody-based applications. IPI’s recombinant version is a fusion of mouse...cellular processes in C. elegans: mScarlet3 for applications needing intense brightness (such as low-expression... -
Hot Plasmids Spring 2024
TypeBlog Post...for microglia research and broader therapeutic applications. Find microglia-targeting AAV plasmids here...reconstituting coding sequences for a range of applications, including CRISPR activation by dCas9-VPR, prime... -
New Acoustic Reporter Genes: Ultrasound Imaging of Gene Expression
TypeBlog Post... the bacteria were injected, limiting their applicability. They also did not scatter ultrasound nonlinearly...ultrasound imaging of nanoscale acoustic biomolecules. Appl. Phys. Lett. 110, 073704 (2017). Hurt, R. C. et ... -
Five Popular Model Organisms, Part 2
TypeBlog Post...Escherichia coli as a Model Organism and Its Application in Biotechnology. In Escherichia coli - Recent...Physiology, Pathogenesis and Biotechnological Applications. InTech. https://doi.org/10.5772/67306 Koornneef... -
Harnessing Bacterial Toxins for Allelic Exchange
TypeBlog Post...Scarless Modification of Proteobacterial Genomes." Applied and environmental microbiology (2019): AEM-00990...chromosomal gene replacement in Escherichia coli." Appl. Environ. Microbiol. 81.15 (2015): 5103-5114. PubMed... -
SARS-CoV-2/COVID-19 Detection Methods Based on CRISPR/Cas
TypeBlog Post...indiscriminate ssDNA cleavage activity which cleaves the supplied fluorescently labelled ssDNA substrates. Upon ...fluorescence can be visualised. Another approach was to apply the same concept to lateral flow strips that contain... -
Multicolor Animals: Using Fluorescent Proteins to Understand Single Cell Behavior
TypeBlog Post...variety of species, cell types, and research applications. Labeling neurons with Brainbow The Lichtman...level of these XFP is not strong enough for all applications. To resolve this, similar systems have been ... -
Plasmids 101: Expressing shRNAs for RNA Interference
TypeBlog Post...world, there is a myriad of tools this could be applied to. When it comes to altering gene expression, ...is an umbrella term for a number of different applications that involve different types of small RNA molecules... -
Hot Biosensors 2022: Year-End Roundup
TypeBlog Post...They generated variants optimized for different applications (v82 has higher affinity for glutamate but slower...lower binding affinities to broaden the range of applications. Image reproduced from Torres Cabán et al. 2022...