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...and Accelerate Research Discoveries) Challenge provides grants for rare disease research. This year is ...rare disease research. Congratulations to the winners! Below, we highlight their research and how they... founded with the mission to support and drive research into CCDS. The brain and muscles have a high metabolic...-36 release,” says Dr. Mark Mellett, a senior researcher at University Hospital Zurich. IL-36 cytokines...intracellular signaling,” says Hébert. Previous research has shown that GNB1 mutations lead to increased...biosensors that would allow us to address many of our research questions,” Hébert says. In the spirit of plasmid...

...prefer to use search, our updated search engine is now more powerful, intuitive, and searches across all ...s new search  Like millions of other websites, we built our new search engine atop Elasticsearch, a powerful...powerful open-source search engine that can scale to search millions of web resources and handle millions...customize the search engine, and a scoping mechanism that allows category-specific, narrow searches. We defined...example, a search scoped to plasmids shows filters for expression and vector type, while a search scoped ... a given resource, and designed the search engine to weight search results differently according to where... our website, including the recent homepage and search tool updates. Now, let’s take a look at the least...

...an improved search algorithm which was trained on key factors from past PubMed user searches, such as clicks...article. Now, search results display a bar graph of the number of papers with your search term published...over time. Creating an alert for a search term helps automate your search for new papers. An alert lets you...relevant to your search terms. Key features Semantic Scholar has several ways to focus your search results. A...year is displayed with your search results and can be used to filter your search to a specific window of ...Meta is not a traditional search engine. Instead, you create your own research feed by entering keywords...suggested related researchers, journals, and concepts to help you expand your search. Results in your ...

...advantage. It wasn’t until I wrote a blog post about a research paper that explored how scientists connect on ...started, but now I’m using social media to help my research and my career. Here are three examples of how ...especially like the pointers on how to use LinkedIn to research potential future employers and to arrange informational...shows quick ways social media can fit into a researcher’s work day. It’s also important to remember that...schedule. Has social media helped you advance your research or career? Share your story in the comments below...

...school students to publish peer-reviewed scientific research. You’ll meet some of the folks behind the journal...and Outro - Interview with high school student researchers Arooba Ahmed, Jiachen Lee, and Jillian Parker...

...meaning they come ready made to accelerate your research.   Why distribute virus? Plasmid distribution...distribution is booming, but, over the years, many researchers we’ve met with have asked if we can help them share...distribution came up time and time again with many researchers lamenting the viral production process while ... We’re reducing this frustration and getting researchers to the experiments they’re interested in faster...processes of viral production and testing so that researchers can use our educational resources and experience... decide to produce virus on their own.Harvard researcher Connie Cepko has been helping us with AAV testing... will further enable scientists and accelerate research." What viral preps are available now? There...

...accelerating this research by helping to make new cancer resources easily accessible to the research community...funding or as much attention collectively from researchers. Scientists, however, have yet to slay the beast...This is why recent work in the field of cancer research has focused on picking apart the complex cellular...improvements in computer modeling have enabled researchers to begin discovering and designing molecules ...specifically to their mutated residues. For Ras researchers, one of the most exciting and relatively new ...clinically relevant as possible. Connecting the research community - Addgene's cancer collection pages ...remain. One of the biggest challenges facing researchers today is the complexity of the pathways involved...

...literature a little bit at a time. Searching for literature My go-to search engines for finding scientific... study, research article etc). There are also numerous options for narrowing down your search and sorting...you to understand the research question that will be addressed. In primary research papers, the introductions... a scientist, it is useful to make literature searching and reading a regular part of your routine. Set...number of papers each week to keep up with the research in your area. When you are in ‘writing-mode’ for...literature are Google Scholar and PubMed. You can search keywords, titles, authors, year, narrow by article...a network with an institutional subscription), archived on PubMed Central, or in preprint onBioRXIV. One...

...discipline for annotation and archiving of data are likely to improve research. What is published is typically... Jim Woodgett is Director of Research at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital...Funded Scientific Research (February 22, 2013)  Who Will Pay for Public Access to Research Data? - by Francine...its data access and sharing policy. Since early March, the open access publisher has required authors ...to where readers may locate data supporting the research reported in PLOS publications. The policy was ...rather it was the result of consultations between researchers and publishers. Nonetheless, the initial release...Perhaps least compelling of these were those from researchers who wanted more time to mine their own data, ...

...a small collection of plasmids for coronavirus research, including a handful of plasmids that have been...many available to scientists in industry. Since March 2020, we have received over 13,000 plasmids requests...plasmids have been used to accelerate COVID-19 research in other labs. Spike protein, variants, and pseudotyping...This plasmid was later used by another team of researchers for neutralization assays, part of a study that...spike variants. You can learn more about their research in this article. To see other plasmids for SARS-CoV...became a great starting point for SARS-CoV-2 researchers to investigate how the virus interacts with human...epithelial cells (Biering et al., 2021). In their search, they found mucins have an important role in viral...

...You've done the research, analyzed your data, and made your tables and figures. Now it's time to write...Phrasebank is a resource for phrases commonly used in research papers or dissertations. Phrases are categorized... to be edited to suit your particular field of research.   Citations tools DOI Citation Formatter Just...check out this related blog post: Early Career Researcher Toolbox: Finding Relevant Papers. These are only...for writing scientific manuscripts: literature searching, reading, and organizing Tips for writing a scientific...

...Sophisticated search You can search for specific plasmids on our website using the search bar found at ...to your research interests. We do this by promoting citation, supporting sophisticated search, and curating... Addgene in a way that another researcher finds useful, that researcher will be able to easily find the...You can search for plasmids by name, PI, Addgene ID number, or keyword. Although an initial search might...can narrow your search results using the filters found on the right side of the search page. A great breakdown...H-index for instance), but these rely upon other researchers being able to find their publications in the ...act directly associates you with a network of researchers who may be working on similar projects and should...

...and technologies in life sciences research. The rare disease research community has certainly noticed: ... Institute sponsors a global competition for researchers working on rare diseases, offering them the chance...year, the BeHEARD (Helping Empower and Accelerate Research Discoveries) Award attracted submissions from ... OuYang, BeHEARD Co-Director in a release. The research teams studying four of those rare diseases will...wrongly diagnosed as a seizure disorder.” In 2012, researchers identified the gene responsible for the disease...in coloring of the hair, skin, and eyes. The researchers found that seven patients diagnosed at their ...

...publications. Google Image Search Google image search is a great tool for searching the entire internet for...you can search for images “Labeled for reuse with modification.” Occasionally Google Image Search results...illustrators with input from life scientists. It’s easy to search the collection and drag and drop an icon onto the...graphics. The tools settings let you tailor your search to particular types of images. For example, by ...resources on the Addgene blog Read our Early Career Researcher Toolbox blog post on social media for scientists...

...Molla, investigator at ICAR-Central National Rice Research Institute. When it comes to genome editing, CRISPR...resonates with nearly every biologist, academic, and researcher. Among the most well-known CRISPR-associated ...capacity to carry large DNA cargos. As a result, the search for smaller, compact genome editors has become ... for multiplexed gene editing applications. As research into TnpB continues to evolve, we anticipate its...al., 2024; Karmakar et al., 2025). We invite researchers to explore and use our TnpB-based genome editing...investigator at the ICAR-Central National Rice Research Institute in India. He specializes in genome editing...

...plasmid pET21a-BirA.   DNA / protein database search and analysis tools Addgene's analyze sequence ...

...different labs and experimental systems in their own research. Cyanobacteria, a phylum of photosynthetic bacteria...

...reports stress the importance of providing authentic research experiences to undergraduate students (1, 2), ...project provides a framework for these undergraduate research questions. The idea is straightforward. Instructors...in the S. cerevisiae lineage (7). In our class research project, students transform S. cerevisiae met ...The plasmids are used as part of a semester-long research course that is part of the biology core curriculum...complementation experiments that are used to answer our research question, the plasmids are also used to teach ...significant gains in both content knowledge and research skills (8). A complete set of student and instructor...particularly interested in strategies to incorporate research into undergraduate courses and in communicating...

...s podcast, we sit down with Wei Leong Chew, a researcher at the Genome Institute of Singapore who recently...to go into genome engineering. Chapter 1: Early research on CRISPR and what it's like to work in a competitive...Genome Institute of Singapore. Chapter 3: Biology research and resources in Singapore. Chapter 4: Life as... AAVs, and more. Chapter 7/Outro: Advice for researchers pursuing careers in academia. Many thanks to...Listen to our interview with synthetic biology researcher Tom Ellis Resources at Addgene.org Find CRISPR...

...writer at the non-profit Fred Hutchinson Cancer Research Center. Susan Keown’s science communication journey...Eye Institute (NEI), where she wrote about NEI research for a general audience. She then got a full time...it.” Science writing at Fred Hutchinson Cancer Research Center Work as a Science Writer at the Hutch ...meetings and Susan is assigned to cover the Clinical Research Division at Fred Hutch, so she attends that division...writing: plain-language stories about Fred Hutch research, pieces for donors such as fundraising materials...did for the Northwest Association of Biomedical Research. She does, however, recommend using Twitter as...