We narrowed to 434 results for: pme

...attended the Developmental Bioelectricity satellite symposium at the 2019 Society for Developmental Biology...signaling mediated by ion-channels and pumps in developmental biology, regeneration studies, and cancer biology...appreciation for the role of ion channels and pumps in developmental biology.  Examples of some ion-channel and ion-pump...whole scientific community. Over the years, developmental biologists and cancer researchers are beginning... decision-making in somatic cell networks. “Developmental bioelectricity is an extremely exciting emerging... "The body electric 2.0: recent advances in developmental bioelectricity for regenerative and synthetic...control polarity during planarian regeneration." Developmental biology 339.1 (2010): 188-199. PubMed PMID: ...

...software development happening at Addgene under the hood. A significant portion of our development may not...productivity. Get to know our software development team and the development process at Addgene. Diversity supports...When you think of Addgene, chances are software development is not one of the things that comes to mind. ...how search works on our site. For Addgenies, development includes everything from tracking plasmids from... supports our innovation Our software development team is a microcosm of Addgene’s work culture. Our developers...Addgene We follow an agile methodology of software development called Scrum. The Scrum framework is based on...on an iterative and collaborative approach to development. Scrum teams plan and break up work into small...

...processes and developments. Model organisms often feature genetic, physiological, or developmental characteristics...expected to shed light on human aging pathological developments (Vieira et al., 2019) Besides their ability ...ideal for observing and manipulating the entire developmental cycle. A majority of studies involving axolotls...biological processes. Many of their genetics and developmental patterns are conserved, making them great models... frog eggs some of the most useful tools in developmental and biomedical research.  Xenopus, aka...used to study vertebrate embryology and cell development. One major resource for frog research is The ...traits that make an ideal model organism: quick development, a large number of offspring (produces many seeds...

...Deficiency Syndromes (CCDS) that present as global developmental delays or autism spectrum disorder. It is estimated...creatine deficiency, which is characterized by development delays, speech delays, seizures, and other symptoms... enhance our ability towards CTD therapeutic development,” says Iyer. Since the RESOLUTE plasmid collection...Though there are IL-36 receptor inhibitors in development, there’s still a lot of mysteries surrounding...in Turner syndrome Turner syndrome (TS) is a developmental disorder where one of the X chromosomes is partially...abnormally deregulated in TS and can lead to cardiac developmental defects. Eight genes from the X chromosome are... in TS cells as a first step to reverse the developmental defects that cause heart problems in TS,” says...

...scientists. Continuing professional development Professional development should be life long, and doesn’t...landing that next coveted job! Professional development (or lack thereof) One of the biggest challenges...programs lack any formal or mandatory professional development training. Further, even for those students and...take responsibility for your own professional development, not count on your institution, program, or adviser... a job fair, and utilizing your local career development center, if one exists. Get online! Review company... career development... professional development...

...organism to study an array of topics including development, genetics, and the nervous system. The fly has...Zebrafish are an ideal model organisms for embryonic development studies as their embryos are completely transparent...transparent. Thus scientists can easily observe early developmental stages which can be difficult in other vertebrate...labelled proteins and tissues to better assess developmental processes. For example, the Stainier lab studied...Brenner brought it into the lab to study neuronal development (Brenner, 1973). C. elegans are small, transparent...visualized in a living organism from embryonic development to adulthood. This ability to genetically manipulate... and processes including the nervous system, development, cell signaling, aging, and mechanotransduction...

...boundaries for both professional and personal development, is essential to excelling in the modern world...mentorship, with the aim of improving professional development and training in a globalized world where individuals... waters of a world in flux. The professional development and networking resources offered by programs ...Spanish mentees, mentors also facilitated the development of bidirectional USA-Europe professional collaborations...sessions, mentors helped mentees create “Career Development Plans” which provided paths to success depending...career opportunities in science as well as the developmental needs and resources needed to pursue them, increased...remarks by the Spanish Secretary of Research, Development, and Innovation, D. Carmen Vela, who reiterated...

...2 hours Equipment needed: PCR machines/Heat blocks, Lateral flow strips, Agarose gel equipment, Fluorescent...However, the limited availability of reagents and equipment and the long turnaround times, have led researchers...copies of RNA per microliter Time: ~40 minutes Equipment required: 37°C heat block and 62°C heat block ...detected – in the zeptomolar range Time: ~1 hour Equipment required: 37°C water bath and 42°C water bath ... in a 40-minute incubation  Time: ~90 minutes Equipment needed: 37°C heat block, LED blue light illuminator... in the paper, likely approximately 1-2 hours Equipment needed: Mini PCR machines by DIY-Bio, P51 cardboard...

...sing with delight? From developmental biology to developing a career Developmental biology caught me early...Science on developmental neurobiology and plant sciences, viewed through the lens of development, cell, and... with information. I am fascinated with how developmental programs unfold, absorbing the stochasticity...followed that avenue with projects studying developmentally programmed regulation of DNA replication and...

...which I use to study gene regulation during developmental processes, CRISPR/Cas9 allows us to delete sequences...selective marker to remain in the edited animal. Development of CRISPR/Cas9 editing strategies in C. elegans...cases, injection of Cre is required, however the development of the self-excising cassette (Dickinson et al..., such as GFP (Paix et al., 2014). A further development of this approach reported in 2017 uses the direct...co-conversion markers. Expanding beyond Cas9 Since the development of CRISPR/Cas9 editing methods, other Cas proteins...genome. Toolkits for editing in C. elegans The development of toolkits such as the SapTrap CRISPR/Cas Toolkit...transformative innovation for our community. Developments in mammalian and yeast cells using modified ...

...interested in learning a new skill, getting access to equipment you don’t have, or maybe both, a visiting scientist...typically). A visiting scientist is distinct from equipment sharing or a collaboration – it requires re-location...Alternatively, the host institute may have a piece of equipment that is custom-built, hard to find, or inaccessible...often have some form of built-in professional development. These programs are often great choices if they...visitation if they have specialized skills and equipment! Preparing for your visit   Design and communicate...

...applications Vaccine development Attenuated and inactivated viruses pioneered vaccine development well over a ... lot, but viruses have stuck around. Vaccine development is moving away from delivery of the actual virus...response even after a single dose. Vaccine development strategies. Image courtesy of Gorry et. al, 2007..., et al. The use of viral vectors in vaccine development. Vaccines. 7, 75 (2022). DOI: https://doi.org...

...and holding one another accountable for their development plans. They all found the support of the group...ongoing support, advice and accountability for development goals. These programs also serve as a great first-time...skills and to hold them accountable for their development plans. However, they find it awkward to ask someone...mentees. Because the participants are at a similar development stage, they have a lot to learn from each other...Experiment with the process. Have each person write a Development Plan. Set concrete goals with input from the ...

...writing, clinical, regulatory, product development, business development, consulting, policy, big data and ...presented may not reflect the most current legal developments.  Further, this post may contain technical inaccuracies...necessary and often overlooked part of career development for foreign national researchers and entrepreneurs... Careers is a life science search and career development firm focused on connecting innovative, entrepreneurial...project management, alliance management, business development, finance, and operations. To learn more, visit...

...counter movement by the public to access basic equipment and to become involved in developing tools and... skills to help do science on the cheap using equipment that would otherwise be discarded. For instance...learned to be resourceful and to repurpose old equipment for new uses. We’ll probably never use the Illumina...optics and fluidics platform it contains. Biotech equipment becomes obsolete amazingly fast, but with a wide...diverse array of capabilities. So don’t throw old equipment away until you ask your local makerspace if they...

...fun science events for adults and professional development opportunities for researchers interested in connecting...Find people who will support your professional development I had a wonderfully supportive mentor and graduate...there were multiple avenues for professional development including workshops and networking events. I ...speakers and participants for our professional development programs. I also reach out to my network to find... professional development...

...particularly related to the neurosciences.  These developments in microscopy coupled with techniques that make...anterior, P= posterior, D= dorsal, V= ventral Developments in light sheet fluorescence microscopy Modern...Murray's clear (11) was mostly used to study the development of vertebrate embryos.  The first 3D reconstructions...Pubmed. J. Huisken, and D.Y.R. Stainier. (2009). Development, 136, 1963–1975. Pubmed. J. Huisken, J. Swoger...J.A Dent, A.G. Polson, M.W. Klymkowsky. (1989) Development, 105.61-74. Pubmed. J. Sharpe, U. Ahlgren, P....

... to invest too much of our internal software development resources into it. At the same time, this project...within my department where we shared materials and equipment between labs. Later I worked with people outside...specific projects where you share methods and equipment between lab groups and departments. You don’t ...-to-date on your collaborators’ professional developments without directly contacting them. One great ...for jobs focusing on: Science Policy, Business Development, Administration and Intellectual Property (Sinche...

...gene, Rett Syndrome is a rare, progressive, neurodevelopmental genetic disorder that affects primarily girls... girls. After a period of seemingly normal development through ages 6 to 18 months, individuals with Rett...suggesting that MECP2 is also essential after development (McGraw et al., 2011). Adrian Bird’s 2007 landmark...gene therapy candidates advanced into clinical development programs in biopharma. AveXis, co-founded by ...Delivery. Molecular Therapy - Methods & Clinical Development 5:106–115 . https://doi.org/10.1016/j.omtm.2017.04.006...

...biological research, medical therapy, and even drug development (Grimm & Lavis, 2022). With the wide breadth ...the filter cubes and filtering settings of the equipment. Systematic evaluation of commercially available...Advancements in dye chemistry have led to the development of more stable, brighter, and specific dyes, ...J., Raverdeau, M., & Voorheis, H. P. (2016). Development of a quantitative fluorescence-based ligand-binding... R., Bousfield, D., & Demokritou, P. (2019). Development & characterization of fluorescently tagged nanocellulose...