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  1. Antibodies 101: Fc Effector Functions

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    Blog Post
    ..., our antibodies have induced “stabbing” and “poisoning,” but let’s be honest, the elimination style the... as phagocytosis.  Other functions We’re still learning about Fc effector functions and all that antibodies...
  2. Understanding GPCR Signaling Using TRUPATH

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    Blog Post
    ...showing the effectiveness of using TRUPATH as a screening technique. Lastly, the activity of both antagonists...plasmids are available as a collection, facilitating screening across the transducerome, to gain a more complete...
  3. Viral Vectors 101: Parts of the AAV Packaging Plasmid

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    Blog Post
    ...serotypes that have thus far been identified: AAV1-11. Nine regions of variability in the cap gene which differ...334 . https://doi.org/10.1007/s40259-017-0234-5  Büning H, Srivastava A (2019) Capsid Modifications for...
  4. Management for Scientists: Giving Feedback

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    Blog Post
    ...bring about change in behaviors and habits in a nonthreatening way. However, I have also found that scientists...interpretation of my feedback to you. What are We Learning: What would have happened if _________? What ...
  5. The Stingy Scientist: How the Baby Gel Box Was Born

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    Blog Post
    ... precious in less resourced areas of the world.  Nina Dudnik, Founder of Seeding Labs, tells the story...bothered by the fact that I was wasting buffer running my tiny gels in a normal gel box. It took a bit...
  6. Tetbow: Bright Multicolor Labeling for Neuronal Tracing

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    Blog Post
    ...Figure 2). We’ve also created constructs with containing chemical tags such as the SNAP-tag, Halo-tag,...17972876. Kohl, Johannes, et al. "Ultrafast tissue staining with chemical tags." Proceedings of the National...
  7. Plasmids 101: Origin of Replication

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    Blog Post
    ...CDF) D Relaxed This table defines common cloning vectors, their copy number, ori, and incompatibility...are especially useful to keep in mind if you are planning to purify your plasmid DNA: The insert Bacteria...
  8. Using Addgene's New Viral Service for Your Research

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    Blog Post
    ...undergo rigorous quality control testing at Addgene meaning they come ready made to accelerate your research...both chemo- and optogenetics. We’re therefore beginning our AAV viral services with these tools. A variety...
  9. Addgene Begins Distribution of Recombinant Antibodies

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    Blog Post
    ...experiments directly from Addgene. How Addgene is Reimagining Antibody Sharing Addgene is building our antibody...well.     References Andrews NP, Boeckman JX, Manning CF, Nguyen JT, Bechtold H, Dumitras C, Gong B, ...
  10. Viral Vectors 101: Transductions

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    Blog Post
    ...time to make virus! The constructed viral vector containing the cargo of interest is then typically transfected...transduced (like a rogue HEK-293 cell). This virus-containing media can then be placed on whatever cells you...
  11. Don’t Wait To Launch Your Health Science Startup

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    Blog Post
    ... like to share my own experiences founding and running miLab to describe some key lessons I learned while... upon these people for guidance.  Before even beginning the process of launching a company, you need to...
Showing: 661 - 680 of 975 results