We narrowed to 191 results for: hwa

...has become a popular tool for probing cellular pathways and mechanisms. CRISPR screening libraries supply...supplied separately). Libraries can target specific pathways or the entire genome at once! Knockout screening...

... in organoid cultures are stable,” said Gerald Schwank, first author of the cystic fibrosis report. “This...Cell. 13, 659-662 (5 December 2013). 8. Gerald Schwank et al. "Functional Repair of CFTR by CRISPR/Cas9...

...trajectories and identify both up- and down-regulated pathways. Individual cellular fates were then matched with...valuable reference if you are looking to understand a pathway, or just looking for the best astrocyte differentiation...

...be applied to an important neuronal signalling pathway - if you’ve got a useful tool, there’s likely someway...networks, and selectively activating signaling pathways. Many scientists came to the Addgene booth to ...

...endogenous RNAi pathways. These mutations however can interfere with other genetic pathways making it difficult...

...To control for protein degradation due to other pathways, it is standard practice to compare degradation...ER, delivered to the vacuole via the secretory pathway, and then cleaved to generate an active form of...

...earning their PhDs (3), showing that the ‘standard’ pathway into academia may in fact be just another ‘alternative...recently launched a survey “Identifying Career Pathways for PhDs in Science”, through which she collects...

...isolated from two patients with cystic fibrosis (Schwank et al). They were able to demonstrate functional...Cas9." Cell Stem Cell. 13, 659-662 (2013). Gerald Schwank et al. "Functional Repair of CFTR by CRISPR/Cas9...

... in different steps in the glycan biosynthetic pathway and have a wide range of clinical manifestations...lines to study how immune processes and biological pathways are altered in PMM2-CDG. These studies are expected...

...further, his lab is now studying how Argonaute pathways may be involved in preventing silencing of self-genes...self-genes. Dr. Mello presented a hypothesis that these pathways are involved in RNA based surveillance of repetitive...

... using the endogenous homology directed repair pathway, a new user-defined DNA sequence (like GFP) can...previously unknown protein functions. References Schwartz, Matthew L. and Eric M. Jorgensen. “SapTrap, a...

...associated with rote memorization of metabolic pathways (precisely the type of exercise Einstein might...undergraduate research experiences (CUREs) as a pathway to diversify science. Evolution and Development...

... exploiting the homology-directed repair (HDR) pathway which occurs in cells at low frequencies and relies...A, A>G, and T>C) installation by base editors. Pathways that compete with the desired outcome are not ...

...since essential and non-essential genes for both pathways had previously been identified (Hart et al, Bassik...systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility." Cell 152.4 (...

...and more, often driven by Rho family signaling pathways. Rho guanine-nucleotide exchange factors (GEFs...phosphatidic acid signaling (such as Hippo, AMPK and mTOR pathways) and to introduce unnatural head groups for applications...

...then cleaved by RISC and degraded. In the miRNA pathway, RISC doesn’t always cleave the mRNA — the bound...Comparison of shRNA and miRNA processing and silencing pathways. Created on BioRender.com.   Expressing shRNAs...

...repaired by the nonhomologous end-joining (NHEJ) pathway, leading to nonspecific nucleotide insertions, ...homology-directed repair (HDR), a distinct cellular DNA repair pathway. Accomplishing this usually involves simultaneously...

...genome editing. The homology-directed repair (HDR) pathway is downregulated in mature tissues - no problem... through the non-homologous end joining (NHEJ) pathway. It’s estimated that very little dystrophin correction...

...silencing pathways: transcriptional and post-transcriptional gene silencing (PTGS). In either pathway, short...

... a microbial pathogen, they trigger signalling pathways that lead to the activation of an immune response...PIG4, SAA, TP53I4 SAA2 serum amyloid A2 - SBDS Shwachman-Bodian-Diamond syndrome CGI-97, FLJ10917, SDS,...of alpha-syn(A53T). Target Accelerator Genetic Pathway Reference Set : From Jesse Boehm , William Hahn...ORFs that represent over 25 cellular signaling pathways and processes. Addgene Blogs Adeno Associated ...